May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

KDGL - Diacylglycerol kinase
UniProt: P0ABN1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10224
Length: 122 (118)
Sequences: 1134
Seq/Len: 9.61

KDGL
Paralog alert: 0.07 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
80_V 91_S 3.575 1.00
20_K 92_G 3.121 1.00
25_A 71_I 2.963 1.00
69_V 72_L 2.897 1.00
26_W 36_G 2.47 1.00
82_R 91_S 2.243 1.00
39_V 63_V 2.086 1.00
64_M 108_V 2.069 1.00
23_R 27_I 1.933 1.00
69_V 105_A 1.851 1.00
71_I 97_M 1.807 1.00
22_L 100_A 1.781 1.00
52_D 55_T 1.773 1.00
90_L 94_A 1.773 1.00
55_T 116_L 1.744 1.00
79_V 94_A 1.699 1.00
46_A 56_R 1.631 1.00
58_L 62_S 1.588 1.00
51_V 116_L 1.579 1.00
26_W 37_V 1.561 1.00
35_E 102_V 1.514 1.00
13_K 16_G 1.51 1.00
65_L 105_A 1.501 1.00
66_V 102_V 1.407 0.99
17_Y 20_K 1.398 0.99
14_A 31_A 1.377 0.99
11_I 34_Q 1.375 0.99
78_A 93_R 1.353 0.99
68_I 105_A 1.343 0.99
14_A 18_S 1.342 0.99
66_V 109_A 1.334 0.99
50_D 56_R 1.285 0.99
32_F 35_E 1.22 0.98
32_F 67_M 1.213 0.98
31_A 35_E 1.207 0.98
67_M 104_I 1.205 0.98
28_N 93_R 1.198 0.98
25_A 32_F 1.195 0.98
71_I 100_A 1.189 0.98
5_T 13_K 1.181 0.97
18_S 99_S 1.181 0.97
61_S 108_V 1.171 0.97
24_A 29_E 1.167 0.97
71_I 104_I 1.166 0.97
36_G 67_M 1.158 0.97
34_Q 38_A 1.155 0.97
74_S 97_M 1.154 0.97
75_A 94_A 1.148 0.97
114_C 118_W 1.147 0.97
74_S 93_R 1.144 0.97
69_V 101_A 1.136 0.97
43_V 63_V 1.121 0.96
64_M 104_I 1.098 0.96
42_A 109_A 1.098 0.96
29_E 78_A 1.095 0.96
79_V 83_I 1.094 0.96
25_A 97_M 1.091 0.95
15_A 103_L 1.078 0.95
59_L 62_S 1.045 0.94
31_A 34_Q 1.024 0.93
83_I 91_S 1.02 0.93
80_V 94_A 1.007 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ze3A611000.032Contact Map0.787
2wwbB10.442612.20.93Contact Map0.039
1rh5B10.40987.40.937Contact Map0.237
3mp7B10.43443.70.945Contact Map0.05
3tx3A20.95082.70.948Contact Map0.291
1pi7A10.25412.60.949Contact Map
3b8cA20.9182.50.95Contact Map0.075
1avoB70.33611.80.953Contact Map0
4ldsA20.51641.80.953Contact Map0.189
4gn0A40.39341.70.954Contact Map0.089

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0176 seconds.