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OPENSEQ.org

MRED - Rod shape-determining protein MreD
UniProt: P0ABH4 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10610
Length: 162 (157)
Sequences: 343
Seq/Len: 2.18

MRED
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
108_M 142_G 2.78 1.00
111_S 141_N 2.708 1.00
19_A 42_I 2.23 1.00
47_I 85_A 2.151 1.00
49_A 153_R 2.039 0.99
38_W 102_Q 1.789 0.98
66_L 81_M 1.749 0.97
149_F 156_R 1.695 0.97
153_R 156_R 1.616 0.95
20_L 39_V 1.536 0.93
94_L 98_L 1.532 0.93
96_R 156_R 1.493 0.92
56_V 82_S 1.442 0.90
45_Y 153_R 1.418 0.89
59_G 95_F 1.412 0.89
49_A 157_Q 1.407 0.89
15_S 19_A 1.348 0.86
107_V 129_S 1.342 0.85
39_V 62_M 1.336 0.85
66_L 144_L 1.315 0.84
115_D 134_V 1.301 0.83
45_Y 96_R 1.29 0.82
88_V 98_L 1.278 0.81
38_W 147_W 1.266 0.80
80_A 107_V 1.265 0.80
76_V 136_W 1.234 0.78
43_L 80_A 1.224 0.77
28_P 38_W 1.223 0.77
44_L 107_V 1.219 0.77
22_L 38_W 1.212 0.76
9_R 13_W 1.203 0.75
37_N 98_L 1.197 0.75
61_V 139_V 1.196 0.75
13_W 58_T 1.195 0.75
134_V 140_V 1.181 0.74
106_V 110_L 1.176 0.73
132_P 136_W 1.173 0.73
15_S 83_I 1.154 0.71
62_M 113_V 1.148 0.71
64_A 109_L 1.148 0.71
40_L 84_I 1.144 0.70
49_A 156_R 1.136 0.69
11_V 161_V 1.128 0.69
59_G 152_M 1.126 0.68
115_D 138_S 1.115 0.67
11_V 141_N 1.115 0.67
44_L 79_L 1.112 0.67
43_L 54_V 1.107 0.66
6_S 11_V 1.094 0.65
60_F 78_V 1.094 0.65
18_I 60_F 1.093 0.65
35_R 120_W 1.092 0.65
86_Y 122_E 1.089 0.65
56_V 110_L 1.082 0.64
21_L 143_V 1.08 0.64
58_T 61_V 1.078 0.63
82_S 116_I 1.074 0.63
86_Y 106_V 1.067 0.62
40_L 78_V 1.065 0.62
38_W 50_L 1.062 0.62
97_N 130_F 1.054 0.61
10_W 127_N 1.052 0.61
120_W 137_S 1.046 0.60
112_L 135_F 1.045 0.60
16_F 62_M 1.044 0.60
13_W 39_V 1.041 0.59
87_L 124_L 1.039 0.59
21_L 41_L 1.038 0.59
54_V 61_V 1.029 0.58
81_M 155_V 1.028 0.58
59_G 85_A 1.027 0.58
61_V 64_A 1.023 0.57
118_V 148_I 1.021 0.57
14_L 18_I 1.021 0.57
74_L 125_V 1.019 0.57
86_Y 111_S 1.012 0.56
95_F 111_S 1.006 0.56
110_L 118_V 1.004 0.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4hzuS10.956822.50.936Contact Map0.143
4huqS10.938313.70.942Contact Map0.117
3rlbA20.95688.30.947Contact Map0.25
3p5nA20.95687.50.949Contact Map0.164
4brcA20.37651.50.964Contact Map0.161
4dveA30.9631.30.965Contact Map0.196
2k8jX10.16671.30.966Contact Map0
3tx3A20.3210.80.97Contact Map0.027
2xxaA20.33330.70.971Contact Map0.197
3pjzA20.41360.60.972Contact Map0.391

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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