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OPENSEQ.org

ATPG - ATP synthase gamma chain
UniProt: P0ABA6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10104
Length: 287 (287)
Sequences: 1908
Seq/Len: 6.65

ATPG
Paralog alert: 0.05 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
82_S 122_G 5.495 1.00
211_D 214_A 3.857 1.00
91_L 235_N 3.702 1.00
239_E 243_R 3.659 1.00
174_K 184_T 3.24 1.00
28_A 240_Q 3.014 1.00
248_K 252_D 2.937 1.00
169_Y 187_Q 2.804 1.00
75_R 112_Q 2.712 1.00
77_G 165_L 2.545 1.00
256_S 260_E 2.421 1.00
18_Q 255_G 2.338 1.00
79_L 156_M 2.308 1.00
277_L 281_V 2.209 1.00
177_N 180_S 2.167 1.00
103_M 115_L 2.143 1.00
167_K 187_Q 2.114 1.00
176_I 182_V 2.11 1.00
75_R 114_D 2.054 1.00
78_Y 102_E 2.011 1.00
91_L 173_N 2.006 1.00
159_A 164_R 1.995 1.00
82_S 96_F 1.971 1.00
240_Q 243_R 1.914 1.00
36_Q 40_A 1.914 1.00
158_Q 162_E 1.801 1.00
98_K 101_A 1.786 1.00
149_L 232_V 1.753 1.00
102_E 105_T 1.749 1.00
100_L 125_F 1.727 1.00
25_E 248_K 1.721 1.00
15_Q 262_Q 1.712 1.00
73_V 166_D 1.683 1.00
71_R 166_D 1.653 1.00
48_T 51_K 1.616 1.00
154_K 158_Q 1.613 1.00
170_I 231_G 1.612 1.00
15_Q 18_Q 1.554 0.99
117_M 122_G 1.552 0.99
66_P 69_E 1.547 0.99
36_Q 175_F 1.533 0.99
171_V 185_I 1.524 0.99
10_K 267_K 1.505 0.99
117_M 133_V 1.503 0.99
80_V 99_L 1.479 0.99
174_K 182_V 1.462 0.99
95_L 171_V 1.46 0.99
173_N 238_S 1.423 0.99
100_L 126_F 1.405 0.99
123_V 136_Q 1.403 0.99
155_V 159_A 1.403 0.99
176_I 180_S 1.392 0.99
114_D 134_V 1.391 0.99
88_C 92_N 1.384 0.98
18_Q 25_E 1.383 0.98
99_L 126_F 1.374 0.98
43_R 234_E 1.371 0.98
88_C 243_R 1.36 0.98
165_L 168_L 1.357 0.98
101_A 105_T 1.347 0.98
279_E 282_S 1.346 0.98
275_Q 279_E 1.342 0.98
264_V 268_A 1.342 0.98
98_K 102_E 1.339 0.98
77_G 168_L 1.336 0.98
96_F 125_F 1.33 0.98
117_M 123_V 1.327 0.98
105_T 109_K 1.321 0.98
268_A 272_S 1.289 0.97
159_A 165_L 1.285 0.97
7_I 265_Y 1.271 0.97
102_E 169_Y 1.267 0.97
27_V 31_K 1.263 0.97
115_L 131_G 1.252 0.97
26_M 206_Y 1.25 0.97
135_A 155_V 1.247 0.96
25_E 244_M 1.22 0.96
98_K 185_I 1.218 0.96
116_A 156_M 1.217 0.96
114_D 132_N 1.208 0.96
99_L 103_M 1.206 0.95
7_I 267_K 1.203 0.95
73_V 167_K 1.202 0.95
29_A 244_M 1.174 0.95
261_L 264_V 1.173 0.95
275_Q 278_T 1.172 0.94
99_L 115_L 1.171 0.94
14_V 17_T 1.17 0.94
99_L 171_V 1.149 0.94
53_I 216_L 1.149 0.94
123_V 138_T 1.121 0.93
31_K 240_Q 1.117 0.92
104_K 108_D 1.117 0.92
281_V 284_A 1.116 0.92
17_T 20_I 1.115 0.92
83_T 92_N 1.111 0.92
28_A 121_K 1.099 0.92
17_T 21_T 1.085 0.91
83_T 173_N 1.083 0.91
17_T 92_N 1.081 0.91
106_W 111_V 1.081 0.91
102_E 171_V 1.081 0.91
28_A 40_A 1.08 0.91
84_D 139_G 1.08 0.91
75_R 164_R 1.078 0.91
104_K 107_T 1.073 0.90
76_V 169_Y 1.073 0.90
118_I 152_P 1.072 0.90
215_L 227_Q 1.061 0.90
96_F 126_F 1.061 0.90
39_M 237_A 1.059 0.90
78_Y 113_C 1.049 0.89
11_I 14_V 1.048 0.89
95_L 99_L 1.046 0.89
156_M 168_L 1.04 0.88
223_Y 227_Q 1.036 0.88
25_E 173_N 1.03 0.88
10_K 221_R 1.03 0.88
32_M 241_A 1.03 0.88
114_D 165_L 1.027 0.88
183_P 234_E 1.023 0.87
178_T 241_A 1.02 0.87
192_P 195_D 1.015 0.87
33_R 37_D 1.009 0.86
153_V 224_V 1.009 0.86
102_E 106_W 1.004 0.86
19_K 88_C 1.001 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2qe7G10.993100-0.02Contact Map0.547
3oaaG40.9965100-0.014Contact Map0.762
2xokG10.94771000.033Contact Map0.668
3ziaG20.94431000.045Contact Map0.669
2ck3G10.94081000.062Contact Map0.695
1fs0G10.80141000.277Contact Map0.813
1qw2A10.3388.80.969Contact Map0.029
1syqB10.08718.40.969Contact Map0.024
1t01B10.08367.30.97Contact Map0.017
2xusA20.163870.97Contact Map0.634

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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