OPENSEQ.org - YCCF - ECOLI GREMLIN

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YCCF - Inner membrane protein YccF

UniProt:	P0AB12	Sequence MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEITKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQCISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE	Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene:	EG12306
Length:	148 (134)
Sequences:	433
Seq/Len:	3.23

YCCF
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Scaled Score	Prob
98_G	115_F	4.703	1.00
102_C	111_G	3.74	1.00
25_T	42_W	2.89	1.00
18_T	49_L	2.835	1.00
98_G	102_C	2.666	1.00
31_L	34_T	2.538	1.00
58_H	127_R	2.526	1.00
88_W	92_L	2.454	1.00
102_C	115_F	2.449	1.00
98_G	111_G	2.43	1.00
29_I	38_T	2.419	1.00
22_L	45_T	2.38	1.00
111_G	115_F	1.979	1.00
100_A	104_S	1.963	1.00
11_V	15_F	1.943	1.00
83_L	122_L	1.685	0.98
25_T	29_I	1.655	0.98
3_T	7_I	1.607	0.98
18_T	22_L	1.599	0.98
83_L	123_W	1.527	0.97
81_F	85_F	1.524	0.97
40_S	43_E	1.489	0.96
29_I	35_L	1.465	0.96
10_F	49_L	1.462	0.95
98_G	104_S	1.407	0.94
96_A	99_I	1.392	0.94
21_W	118_A	1.29	0.90
68_N	71_L	1.288	0.90
13_G	17_T	1.284	0.90
15_F	19_L	1.267	0.89
26_L	85_F	1.246	0.88
113_A	116_K	1.243	0.87
59_V	128_R	1.242	0.87
28_S	31_L	1.241	0.87
76_T	80_I	1.205	0.85
20_G	93_M	1.191	0.84
20_G	49_L	1.177	0.83
40_S	125_V	1.176	0.83
19_L	33_F	1.146	0.81
5_L	8_L	1.125	0.79
1_M	8_L	1.117	0.79
29_I	42_W	1.082	0.75
28_S	34_T	1.077	0.75
35_L	38_T	1.067	0.74
20_G	88_W	1.056	0.73
94_H	114_N	1.054	0.73
30_V	33_F	1.051	0.72
90_L	121_A	1.048	0.72
47_L	56_A	1.044	0.72
102_C	108_I	1.042	0.71
4_V	30_V	1.036	0.71
97_T	114_N	1.014	0.68
63_N	72_N	1.009	0.68
86_F	89_W	1.007	0.68
10_F	18_T	1.007	0.68
22_L	26_L	1.004	0.67
13_G	101_Q	1.002	0.67

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling

HHsearch Results:

PDB	Chains	Cov	P(%)	HHΔ		Acc
2zi0A	2	0.25	4.9	0.961	Contact Map	1
1qfqB	1	0.1014	4.4	0.962	Contact Map
1xioA	1	0.8108	3.3	0.964	Contact Map	0.297
4il3A	2	0.8716	2.6	0.966	Contact Map	0.435
3tuiA	4	0.8784	2.6	0.966	Contact Map	0.294
2ykaB	1	0.1554	2.1	0.968	Contact Map
3s6pE	4	0.4865	1.6	0.97	Contact Map	0
4aw6A	4	0.8919	1.5	0.97	Contact Map	0.295
1ji6A	1	0.3986	1.2	0.972	Contact Map	0.136
3ondA	2	0.3378	1.2	0.972	Contact Map	0

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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