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RL13 - 50S ribosomal protein L13
UniProt: P0AA10 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10874
Length: 142 (142)
Sequences: 1457
Seq/Len: 10.26

RL13
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
14_D 138_Q 3.515 1.00
32_L 56_V 3.277 1.00
70_T 90_E 3.202 1.00
25_L 64_V 2.936 1.00
64_V 89_F 2.773 1.00
7_K 10_T 2.742 1.00
96_R 99_R 2.739 1.00
75_Y 86_Q 2.416 1.00
21_T 61_K 2.215 1.00
125_Y 131_N 2.214 1.00
73_V 86_Q 2.211 1.00
53_Y 123_K 2.13 1.00
69_R 89_F 2.003 1.00
32_L 105_V 1.97 1.00
69_R 93_I 1.969 1.00
125_Y 132_H 1.951 1.00
29_A 104_A 1.939 1.00
75_Y 84_I 1.886 1.00
30_T 34_R 1.845 1.00
87_A 92_M 1.771 1.00
93_I 100_V 1.77 1.00
22_G 63_A 1.745 1.00
99_R 102_E 1.726 1.00
67_N 71_D 1.713 1.00
88_T 91_E 1.695 1.00
11_V 48_V 1.667 1.00
57_L 128_N 1.653 1.00
73_V 88_T 1.636 1.00
35_R 40_H 1.62 1.00
23_K 141_D 1.577 1.00
101_I 105_V 1.553 1.00
91_E 95_R 1.549 1.00
41_K 52_D 1.53 1.00
18_V 32_L 1.516 1.00
6_A 45_T 1.503 1.00
17_V 57_L 1.497 1.00
5_T 47_H 1.495 1.00
35_R 140_L 1.488 1.00
117_A 120_R 1.485 1.00
67_N 70_T 1.479 1.00
89_F 93_I 1.475 1.00
89_F 100_V 1.411 1.00
74_Y 89_F 1.4 0.99
35_R 54_I 1.396 0.99
60_D 127_G 1.392 0.99
13_R 121_K 1.392 0.99
87_A 95_R 1.39 0.99
102_E 119_F 1.376 0.99
37_R 44_Y 1.354 0.99
17_V 55_I 1.325 0.99
21_T 128_N 1.324 0.99
25_L 62_V 1.312 0.99
76_H 87_A 1.224 0.98
109_L 119_F 1.213 0.98
31_E 34_R 1.211 0.98
129_E 133_A 1.194 0.98
78_T 85_K 1.19 0.98
60_D 126_A 1.186 0.98
59_A 124_V 1.177 0.98
20_A 28_L 1.174 0.98
23_K 31_E 1.164 0.97
16_Y 140_L 1.162 0.97
21_T 24_T 1.132 0.97
99_R 103_I 1.124 0.97
43_E 50_T 1.121 0.97
7_K 48_V 1.098 0.96
87_A 91_E 1.092 0.96
97_P 126_A 1.09 0.96
103_I 106_K 1.075 0.95
50_T 121_K 1.071 0.95
109_L 115_G 1.068 0.95
69_R 100_V 1.064 0.95
40_H 52_D 1.029 0.94
59_A 97_P 1.005 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kixJ111000.059Contact Map0.71
3f1fN10.98591000.066Contact Map0.684
3v2dN10.98591000.066Contact Map0.847
2zjrG10.98591000.067Contact Map0.478
3bboL111000.068Contact Map0.651
3j3wJ111000.069Contact Map0.544
2ftcH111000.119Contact Map0.02
3zf7O10.91551000.309Contact Map0.379
1j3aA10.81691000.329Contact Map0.686
1vq8J10.82391000.336Contact Map0.44

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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