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OPENSEQ.org
YIAG - Uncharacterized HTH-type transcriptional regulator YiaG
UniProt: P0A9V5 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12624
Length: 96 (91)
Sequences: 337
Seq/Len: 3.70
YIAG
Paralog alert: 0.48 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
10_L 13_S 4.155 1.00
61_A 64_K 3.411 1.00
14_L 17_I 2.137 1.00
65_E 70_R 1.797 0.99
11_L 14_L 1.768 0.99
48_K 62_M 1.749 0.99
14_L 18_V 1.62 0.98
5_D 8_H 1.589 0.98
63_V 79_K 1.576 0.98
17_I 20_K 1.559 0.98
87_N 93_Q 1.484 0.97
12_S 16_Q 1.471 0.97
44_G 85_Q 1.449 0.96
83_L 90_L 1.442 0.96
21_D 24_Q 1.439 0.96
13_S 16_Q 1.42 0.96
89_A 93_Q 1.414 0.96
45_T 58_V 1.387 0.95
71_V 75_S 1.312 0.93
52_F 63_V 1.31 0.93
11_L 15_E 1.301 0.92
43_K 47_L 1.299 0.92
47_L 51_D 1.293 0.92
57_G 78_L 1.291 0.92
35_C 57_G 1.288 0.92
58_V 84_I 1.204 0.88
37_E 40_Q 1.187 0.87
13_S 55_V 1.15 0.84
49_I 64_K 1.124 0.82
58_V 74_S 1.092 0.80
56_L 74_S 1.087 0.79
19_F 24_Q 1.061 0.77
62_M 73_P 1.058 0.77
84_I 91_S 1.054 0.76
51_D 71_V 1.05 0.76
70_R 74_S 1.043 0.75
68_S 82_R 1.038 0.75
54_R 92_K 1.037 0.75
60_V 64_K 1.027 0.74
33_T 54_R 1.016 0.73
7_M 10_L 1.014 0.72
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1s4kA20.687599.20.584Contact Map0.358
3o9xA20.916798.90.633Contact Map0.346
2ppxA10.854298.60.66Contact Map0.398
3fmyA10.760498.50.672Contact Map0.352
3fymA10.687598.20.704Contact Map0.269
3kxaA4198.10.711Contact Map0.361
4gqmA10.770898.10.712Contact Map0.395
1rzsA10.593898.10.713Contact Map0.284
2p5tA40.6667980.714Contact Map
2wusR20.7292980.714Contact Map0.373
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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