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OPENSEQ.org

FER - 2Fe-2S ferredoxin
UniProt: P0A9R4 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11328
Length: 111 (110)
Sequences: 1088
Seq/Len: 9.89

FER
Paralog alert: 0.12 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
21_A 30_A 3.673 1.00
21_A 91_V 3.071 1.00
6_I 31_A 2.692 1.00
56_R 99_E 2.492 1.00
29_D 44_K 2.426 1.00
54_I 80_E 2.423 1.00
52_H 83_S 2.315 1.00
27_I 98_V 2.301 1.00
27_I 89_A 2.151 1.00
23_S 93_D 2.048 1.00
3_K 20_E 2.003 1.00
5_V 18_V 1.979 1.00
22_N 25_E 1.973 1.00
65_S 70_D 1.934 1.00
25_E 33_R 1.736 1.00
2_P 91_V 1.721 1.00
54_I 82_E 1.701 1.00
6_I 30_A 1.568 1.00
8_P 17_A 1.519 1.00
3_K 18_V 1.45 1.00
40_H 86_S 1.441 1.00
56_R 97_V 1.422 1.00
25_E 29_D 1.41 0.99
71_D 74_D 1.39 0.99
62_L 89_A 1.36 0.99
6_I 19_L 1.33 0.99
25_E 30_A 1.304 0.99
45_S 72_M 1.257 0.99
31_A 36_I 1.256 0.99
56_R 80_E 1.247 0.98
17_A 100_I 1.243 0.98
49_T 76_A 1.195 0.98
71_D 75_K 1.193 0.98
2_P 95_D 1.175 0.98
28_L 44_K 1.161 0.97
21_A 25_E 1.152 0.97
8_P 100_I 1.142 0.97
9_H 12_L 1.134 0.97
55_V 62_L 1.131 0.97
28_L 86_S 1.122 0.96
60_D 64_E 1.116 0.96
59_F 95_D 1.105 0.96
54_I 78_G 1.072 0.95
73_L 79_L 1.069 0.95
7_L 97_V 1.049 0.94
47_A 72_M 1.02 0.93
28_L 38_I 1.007 0.93
53_C 86_S 1.003 0.92
26_T 90_R 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ah7A1199.90.354Contact Map0.756
1i7hA3199.90.36Contact Map0.808
3huiA10.918999.90.39Contact Map0.785
2y5cA20.918999.90.396Contact Map0.805
3lxfA50.900999.90.398Contact Map0.708
3n9zC20.97399.90.4Contact Map0.456
1xlqA30.909999.90.4Contact Map0.807
1uwmA10.909999.90.404Contact Map0.816
2bt6A20.882999.80.409Contact Map0.785
2wlbA20.882999.80.412Contact Map0.762

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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