| UniProt: | P0A9M2 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG20098 | ||
| Length: | 178 (172) | ||
| Sequences: | 1424 | ||
| Seq/Len: | 8.28 |
| HPRT
Paralog alert: 0.08 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 28_R | 143_F | 4.253 | 1.00 | |
| 124_A | 142_E | 3.891 | 1.00 | |
| 94_D | 121_K | 3.023 | 1.00 | |
| 40_G | 49_M | 2.809 | 1.00 | |
| 17_R | 20_E | 2.759 | 1.00 | |
| 10_P | 13_E | 2.7 | 1.00 | |
| 112_R | 116_S | 2.666 | 1.00 | |
| 17_R | 146_F | 2.639 | 1.00 | |
| 91_R | 119_E | 2.427 | 1.00 | |
| 94_D | 122_S | 2.382 | 1.00 | |
| 38_L | 53_C | 2.252 | 1.00 | |
| 19_A | 55_E | 2.236 | 1.00 | |
| 120_P | 123_L | 2.234 | 1.00 | |
| 26_T | 57_Q | 2.212 | 1.00 | |
| 41_L | 111_V | 2.21 | 1.00 | |
| 27_E | 30_K | 1.969 | 1.00 | |
| 22_G | 26_T | 1.965 | 1.00 | |
| 26_T | 58_V | 1.881 | 1.00 | |
| 129_L | 153_V | 1.862 | 1.00 | |
| 112_R | 125_I | 1.846 | 1.00 | |
| 29_Y | 122_S | 1.836 | 1.00 | |
| 148_I | 153_V | 1.829 | 1.00 | |
| 11_E | 15_K | 1.819 | 1.00 | |
| 61_E | 93_K | 1.809 | 1.00 | |
| 36_M | 96_L | 1.799 | 1.00 | |
| 109_S | 113_E | 1.754 | 1.00 | |
| 129_L | 170_I | 1.742 | 1.00 | |
| 72_S | 161_A | 1.697 | 1.00 | |
| 36_M | 93_K | 1.696 | 1.00 | |
| 106_N | 136_E | 1.691 | 1.00 | |
| 51_D | 54_R | 1.679 | 1.00 | |
| 51_D | 156_Y | 1.675 | 1.00 | |
| 21_L | 145_G | 1.648 | 1.00 | |
| 34_S | 94_D | 1.644 | 1.00 | |
| 84_K | 87_D | 1.624 | 1.00 | |
| 130_D | 135_R | 1.591 | 1.00 | |
| 17_R | 24_Q | 1.557 | 1.00 | |
| 6_E | 151_E | 1.555 | 1.00 | |
| 22_G | 56_V | 1.547 | 1.00 | |
| 102_I | 141_V | 1.536 | 1.00 | |
| 25_I | 52_L | 1.517 | 1.00 | |
| 38_L | 96_L | 1.502 | 1.00 | |
| 46_F | 62_V | 1.49 | 1.00 | |
| 130_D | 147_S | 1.482 | 1.00 | |
| 15_K | 55_E | 1.468 | 0.99 | |
| 21_L | 126_C | 1.466 | 0.99 | |
| 47_M | 53_C | 1.461 | 0.99 | |
| 129_L | 148_I | 1.437 | 0.99 | |
| 19_A | 23_R | 1.429 | 0.99 | |
| 41_L | 65_M | 1.416 | 0.99 | |
| 29_Y | 124_A | 1.388 | 0.99 | |
| 25_I | 56_V | 1.356 | 0.99 | |
| 23_R | 27_E | 1.354 | 0.99 | |
| 151_E | 172_K | 1.348 | 0.99 | |
| 28_R | 124_A | 1.347 | 0.99 | |
| 85_D | 118_R | 1.338 | 0.99 | |
| 34_S | 121_K | 1.329 | 0.99 | |
| 114_I | 118_R | 1.29 | 0.98 | |
| 92_G | 121_K | 1.278 | 0.98 | |
| 11_E | 55_E | 1.258 | 0.98 | |
| 134_R | 150_D | 1.253 | 0.98 | |
| 40_G | 45_S | 1.244 | 0.98 | |
| 24_Q | 28_R | 1.225 | 0.97 | |
| 50_A | 54_R | 1.223 | 0.97 | |
| 133_S | 150_D | 1.222 | 0.97 | |
| 29_Y | 94_D | 1.196 | 0.97 | |
| 24_Q | 27_E | 1.187 | 0.97 | |
| 16_A | 20_E | 1.164 | 0.96 | |
| 99_E | 127_T | 1.161 | 0.96 | |
| 31_D | 34_S | 1.153 | 0.96 | |
| 141_V | 144_I | 1.14 | 0.96 | |
| 46_F | 50_A | 1.13 | 0.95 | |
| 116_S | 123_L | 1.13 | 0.95 | |
| 25_I | 126_C | 1.121 | 0.95 | |
| 43_R | 162_Q | 1.108 | 0.95 | |
| 26_T | 56_V | 1.101 | 0.94 | |
| 60_H | 166_H | 1.093 | 0.94 | |
| 11_E | 168_P | 1.084 | 0.94 | |
| 22_G | 55_E | 1.081 | 0.94 | |
| 47_M | 54_R | 1.076 | 0.93 | |
| 133_S | 147_S | 1.069 | 0.93 | |
| 63_D | 84_K | 1.063 | 0.93 | |
| 23_R | 57_Q | 1.061 | 0.93 | |
| 153_V | 158_I | 1.059 | 0.93 | |
| 6_E | 174_I | 1.053 | 0.92 | |
| 71_G | 161_A | 1.05 | 0.92 | |
| 20_E | 146_F | 1.046 | 0.92 | |
| 90_I | 120_P | 1.036 | 0.92 | |
| 37_V | 88_E | 1.032 | 0.91 | |
| 113_E | 117_L | 1.011 | 0.90 | |
| 52_L | 98_V | 1.008 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3o7mA | 4 | 0.9888 | 100 | 0.388 | Contact Map | 0.855 |
| 3ozfA | 4 | 0.9831 | 100 | 0.389 | Contact Map | 0.682 |
| 2jbhA | 2 | 0.9831 | 100 | 0.392 | Contact Map | 0.692 |
| 1z7gA | 4 | 0.9831 | 100 | 0.393 | Contact Map | 0.735 |
| 4lyyA | 4 | 0.9944 | 100 | 0.393 | Contact Map | 0.865 |
| 1pzmA | 2 | 1 | 100 | 0.395 | Contact Map | 0.826 |
| 1tc1A | 2 | 0.9888 | 100 | 0.398 | Contact Map | 0.83 |
| 1fsgA | 2 | 0.9831 | 100 | 0.4 | Contact Map | 0.607 |
| 2gebA | 1 | 0.9888 | 100 | 0.408 | Contact Map | 0.775 |
| 1hgxA | 2 | 0.9831 | 100 | 0.411 | Contact Map | 0.767 |
Sequence Conservation (Image Generated using WebLogo v3)