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OPENSEQ.org
YQGE - UPF0301 protein YqgE
UniProt: P0A8W5 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13289
Length: 187 (187)
Sequences: 862
Seq/Len: 4.61
YQGE
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
22_S 41_K 3.348 1.00
6_H 151_P 2.957 1.00
23_V 39_V 2.705 1.00
37_I 127_A 2.621 1.00
155_N 159_K 2.602 1.00
153_D 172_L 2.31 1.00
140_Q 144_D 2.075 1.00
23_V 166_W 1.857 1.00
123_D 159_K 1.792 1.00
14_L 146_A 1.771 1.00
73_M 162_I 1.755 1.00
142_I 146_A 1.731 0.99
18_I 41_K 1.716 0.99
14_L 18_I 1.643 0.99
22_S 38_I 1.611 0.99
25_Y 103_T 1.604 0.99
77_P 129_G 1.598 0.99
98_R 101_D 1.549 0.99
7_F 39_V 1.523 0.98
28_E 32_N 1.481 0.98
27_C 158_F 1.459 0.98
43_L 74_L 1.423 0.97
56_K 157_L 1.41 0.97
88_T 123_D 1.389 0.97
34_A 139_E 1.378 0.97
131_A 151_P 1.376 0.96
5_H 25_Y 1.363 0.96
52_L 112_L 1.342 0.96
170_A 177_I 1.327 0.95
9_I 150_A 1.31 0.95
24_V 146_A 1.285 0.94
167_R 176_D 1.278 0.94
11_M 148_L 1.276 0.94
145_N 148_L 1.257 0.93
21_R 166_W 1.254 0.93
160_T 168_E 1.247 0.93
9_I 51_I 1.246 0.93
119_K 164_D 1.242 0.93
13_A 41_K 1.232 0.92
30_N 80_E 1.222 0.92
6_H 149_T 1.216 0.92
17_P 166_W 1.203 0.91
149_T 184_A 1.195 0.91
34_A 158_F 1.183 0.90
12_P 16_D 1.181 0.90
156_I 175_V 1.178 0.90
161_P 164_D 1.171 0.90
18_I 22_S 1.165 0.89
159_K 168_E 1.156 0.89
165_R 170_A 1.15 0.89
78_L 132_S 1.146 0.88
25_Y 86_L 1.141 0.88
176_D 179_T 1.139 0.88
24_V 38_I 1.138 0.88
7_F 149_T 1.136 0.88
11_M 145_N 1.131 0.87
61_P 69_D 1.123 0.87
136_G 139_E 1.123 0.87
5_H 27_C 1.122 0.87
142_I 149_T 1.117 0.87
102_N 184_A 1.117 0.87
100_S 103_T 1.109 0.86
63_D 67_R 1.104 0.86
96_S 104_V 1.096 0.85
148_L 180_M 1.092 0.85
72_V 174_G 1.092 0.85
84_F 106_T 1.077 0.84
166_W 170_A 1.075 0.84
122_S 153_D 1.072 0.83
45_N 66_I 1.066 0.83
93_F 111_V 1.066 0.83
5_H 23_V 1.064 0.83
37_I 70_K 1.063 0.83
84_F 128_L 1.061 0.82
116_G 120_Q 1.056 0.82
48_I 52_L 1.054 0.82
103_T 157_L 1.047 0.81
73_M 125_L 1.045 0.81
106_T 110_D 1.029 0.80
139_E 152_A 1.029 0.80
19_F 77_P 1.029 0.80
99_I 103_T 1.027 0.80
114_T 120_Q 1.025 0.79
96_S 100_S 1.024 0.79
35_M 84_F 1.023 0.79
13_A 37_I 1.022 0.79
81_D 126_V 1.021 0.79
170_A 178_L 1.019 0.79
14_L 41_K 1.012 0.78
58_T 61_P 1.007 0.78
24_V 120_Q 1.003 0.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2hafA10.99471000.037Contact Map0.509
2gzoA10.98931000.042Contact Map0.365
2ew0A10.96791000.055Contact Map0.511
2do8A10.97861000.056Contact Map0.264
2gs5A10.95191000.126Contact Map0.35
1wfxA10.66319.20.958Contact Map0.057
4fvcA60.43325.70.962Contact Map0.014
1x0gA40.43854.80.963Contact Map0.147
3tqfA20.43324.70.963Contact Map0.181
1nwbA10.50273.70.965Contact Map0.023
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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