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OPENSEQ.org
YAAA - UPF0246 protein YaaA
UniProt: P0A8I3 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10011
Length: 258 (257)
Sequences: 948
Seq/Len: 3.69
YAAA
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
52_I 56_L 4.001 1.00
30_N 150_I 3.399 1.00
142_D 145_Q 3.117 1.00
100_D 223_R 2.796 1.00
241_D 244_S 2.623 1.00
4_L 167_V 2.597 1.00
81_L 101_F 2.577 1.00
92_Q 95_T 2.532 1.00
187_E 248_G 2.49 1.00
60_N 63_R 2.443 1.00
226_K 229_Q 2.315 1.00
17_L 77_R 2.298 1.00
47_S 54_D 2.248 1.00
168_I 219_I 2.236 1.00
104_A 220_I 2.219 1.00
100_D 221_E 2.199 1.00
228_E 231_T 2.142 1.00
3_I 219_I 2.124 1.00
10_T 84_K 2.103 1.00
61_A 65_H 2.051 1.00
241_D 253_K 1.991 1.00
217_R 221_E 1.967 1.00
26_E 154_K 1.908 1.00
149_D 153_N 1.876 1.00
15_S 77_R 1.844 1.00
151_I 178_S 1.841 1.00
103_F 107_H 1.812 0.99
5_I 216_S 1.783 0.99
58_G 62_A 1.772 0.99
96_F 100_D 1.755 0.99
38_A 64_F 1.732 0.99
194_L 253_K 1.7 0.99
31_S 67_W 1.696 0.99
137_N 140_G 1.684 0.99
5_I 108_L 1.669 0.99
100_D 220_I 1.668 0.99
97_S 100_D 1.645 0.99
227_P 250_L 1.631 0.99
96_F 101_F 1.63 0.99
246_S 249_E 1.615 0.98
5_I 87_V 1.591 0.98
244_S 253_K 1.537 0.98
86_D 206_F 1.527 0.97
62_A 66_D 1.527 0.97
96_F 217_R 1.524 0.97
231_T 250_L 1.523 0.97
219_I 224_L 1.52 0.97
59_I 63_R 1.507 0.97
196_E 256_E 1.464 0.97
195_D 205_S 1.453 0.96
46_I 52_I 1.443 0.96
105_Q 121_L 1.414 0.96
192_V 249_E 1.38 0.95
151_I 179_V 1.374 0.95
76_A 123_L 1.352 0.94
196_E 255_Y 1.35 0.94
95_T 221_E 1.348 0.94
99_D 223_R 1.342 0.94
154_K 157_E 1.329 0.93
214_L 236_E 1.316 0.93
141_K 145_Q 1.309 0.92
90_G 210_K 1.307 0.92
221_E 235_S 1.302 0.92
13_Y 82_A 1.294 0.92
109_R 158_A 1.291 0.92
81_L 96_F 1.289 0.92
26_E 158_A 1.288 0.92
28_L 70_D 1.287 0.92
104_A 216_S 1.285 0.92
84_K 89_T 1.284 0.92
8_A 11_L 1.278 0.91
239_F 255_Y 1.274 0.91
168_I 191_P 1.262 0.91
219_I 230_L 1.255 0.90
191_P 250_L 1.252 0.90
247_N 250_L 1.25 0.90
103_F 220_I 1.249 0.90
113_G 131_M 1.231 0.89
173_D 190_K 1.227 0.89
37_E 41_L 1.226 0.89
52_I 57_A 1.222 0.89
208_A 212_R 1.222 0.89
91_L 216_S 1.222 0.89
201_F 253_K 1.218 0.88
37_E 138_A 1.218 0.88
240_F 250_L 1.214 0.88
31_S 146_F 1.198 0.87
37_E 135_L 1.193 0.87
84_K 94_E 1.183 0.86
96_F 104_A 1.182 0.86
166_V 187_E 1.172 0.86
27_L 196_E 1.157 0.85
165_N 187_E 1.155 0.85
42_T 45_Q 1.126 0.82
87_V 206_F 1.119 0.82
149_D 180_K 1.109 0.81
216_S 220_I 1.105 0.81
190_K 249_E 1.103 0.81
152_T 181_P 1.098 0.80
207_Y 254_R 1.098 0.80
21_R 102_D 1.092 0.80
224_L 229_Q 1.086 0.79
2_L 165_N 1.08 0.79
226_K 250_L 1.071 0.78
35_I 114_L 1.07 0.78
96_F 221_E 1.065 0.77
87_V 204_I 1.047 0.76
30_N 139_R 1.03 0.74
79_A 88_Y 1.03 0.74
62_A 65_H 1.027 0.74
47_S 57_A 1.024 0.73
165_N 185_N 1.024 0.73
83_F 132_G 1.022 0.73
158_A 162_Q 1.013 0.72
155_L 184_L 1.011 0.72
12_D 84_K 1.01 0.72
27_L 117_V 1.008 0.72
158_A 163_G 1.006 0.71
95_T 217_R 1.003 0.71
91_L 96_F 1.003 0.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2duyA10.255813.30.966Contact Map0.769
3c65A10.251913.10.966Contact Map0.04
2k9lA10.24818.10.969Contact Map0.571
3arcU20.32958.10.969Contact Map0.515
2yfvC10.23647.40.97Contact Map0.707
4e1pA20.17055.80.971Contact Map0.128
2rklA60.20544.90.972Contact Map0.417
1fs1B20.22484.80.972Contact Map1
2lxrA10.26744.70.972Contact Map0.242
3eyiA20.25974.10.973Contact Map0.568
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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