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OPENSEQ.org

RUVX - Putative Holliday junction resolvase
UniProt: P0A8I1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13290
Length: 138 (135)
Sequences: 1682
Seq/Len: 12.46

RUVX
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
80_A 93_L 3.615 1.00
131_E 135_E 3.36 1.00
69_E 77_R 3.306 1.00
56_E 92_K 3.141 1.00
31_P 44_I 3.081 1.00
64_N 68_T 2.315 1.00
70_Q 73_T 2.215 1.00
5_L 56_E 2.146 1.00
65_M 98_L 2.126 1.00
49_L 57_I 1.983 1.00
99_S 128_I 1.953 1.00
35_A 41_D 1.95 1.00
12_T 75_R 1.943 1.00
32_A 123_S 1.848 1.00
59_V 80_A 1.782 1.00
94_H 132_S 1.717 1.00
46_E 87_F 1.7 1.00
44_I 47_R 1.691 1.00
69_E 73_T 1.685 1.00
19_V 30_L 1.672 1.00
61_L 77_R 1.653 1.00
46_E 86_R 1.651 1.00
81_N 84_H 1.649 1.00
3_G 55_D 1.618 1.00
17_V 48_L 1.594 1.00
10_F 59_V 1.565 1.00
124_A 127_V 1.52 1.00
104_R 121_V 1.518 1.00
46_E 50_K 1.509 1.00
56_E 90_E 1.496 1.00
105_S 109_E 1.482 1.00
6_L 54_P 1.474 1.00
65_M 97_R 1.469 1.00
8_F 17_V 1.466 1.00
61_L 93_L 1.46 1.00
47_R 51_E 1.438 1.00
92_K 133_Y 1.419 1.00
12_T 72_L 1.409 1.00
15_I 79_F 1.372 0.99
57_I 89_V 1.372 0.99
72_L 75_R 1.361 0.99
76_A 80_A 1.337 0.99
23_I 26_T 1.329 0.99
42_W 82_R 1.304 0.99
30_L 52_W 1.268 0.99
4_T 52_W 1.256 0.99
29_P 123_S 1.238 0.98
19_V 54_P 1.223 0.98
10_F 79_F 1.215 0.98
57_I 87_F 1.213 0.98
77_R 93_L 1.201 0.98
58_I 92_K 1.198 0.98
112_G 116_L 1.137 0.97
15_I 41_D 1.134 0.97
6_L 48_L 1.097 0.96
49_L 87_F 1.094 0.96
20_G 134_F 1.091 0.96
80_A 84_H 1.056 0.95
72_L 76_A 1.047 0.94
107_L 120_K 1.041 0.94
64_N 71_P 1.036 0.94
20_G 24_T 1.014 0.93
106_G 124_A 1.008 0.93
19_V 52_W 1.007 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1nu0A211000.183Contact Map0.813
1vhxA211000.198Contact Map0.732
1iv0A10.710199.90.443Contact Map0.412
4ep4A20.94299.70.597Contact Map0.621
3bzcA10.94298.60.76Contact Map0.512
1hjrA40.949397.80.809Contact Map0.685
3psiA10.884195.80.853Contact Map0.485
3psfA10.884195.60.855Contact Map0.504
3vovA40.9493940.867Contact Map0.664
3epqA10.963893.90.868Contact Map0.647

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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