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OPENSEQ.org
YMDB - O-acetyl-ADP-ribose deacetylase
UniProt: P0A8D6 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13874
Length: 177 (171)
Sequences: 1464
Seq/Len: 8.56
YMDB
Paralog alert: 0.09 [within 20: 0.02] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
141_V 156_F 3.144 1.00
49_A 71_G 3.102 1.00
114_T 152_E 2.903 1.00
42_A 46_L 2.898 1.00
99_D 103_N 2.622 1.00
6_H 153_Q 2.594 1.00
49_A 69_L 2.54 1.00
15_L 155_Y 2.489 1.00
160_D 163_N 2.214 1.00
30_G 35_D 2.191 1.00
45_A 72_D 2.161 1.00
67_I 107_L 2.103 1.00
62_T 96_L 2.066 1.00
128_Y 132_A 1.999 1.00
64_H 103_N 1.993 1.00
67_I 111_N 1.919 1.00
102_L 140_T 1.917 1.00
9_Q 161_E 1.915 1.00
20_I 38_I 1.904 1.00
130_R 163_N 1.903 1.00
94_D 132_A 1.875 1.00
128_Y 136_I 1.854 1.00
70_A 75_A 1.807 1.00
161_E 165_H 1.767 1.00
103_N 106_R 1.734 1.00
89_G 93_E 1.661 1.00
14_K 41_A 1.651 1.00
42_A 71_G 1.6 1.00
164_A 168_E 1.563 1.00
19_V 113_Y 1.563 1.00
81_T 104_S 1.537 1.00
98_Q 140_T 1.536 1.00
53_V 66_V 1.531 1.00
47_L 51_L 1.517 1.00
83_G 122_S 1.512 1.00
46_L 71_G 1.474 1.00
120_A 123_T 1.47 1.00
86_W 93_E 1.464 0.99
130_R 166_L 1.458 0.99
166_L 170_L 1.456 0.99
109_A 144_F 1.444 0.99
120_A 167_Y 1.418 0.99
77_A 113_Y 1.415 0.99
65_A 79_V 1.414 0.99
35_D 39_H 1.403 0.99
15_L 157_V 1.39 0.99
130_R 162_E 1.343 0.99
140_T 143_E 1.307 0.99
23_A 34_V 1.306 0.99
141_V 154_V 1.302 0.99
16_A 74_P 1.265 0.98
107_L 110_A 1.238 0.98
131_A 169_R 1.229 0.98
163_N 167_Y 1.199 0.97
101_Y 137_A 1.184 0.97
37_A 41_A 1.18 0.97
120_A 130_R 1.177 0.97
8_V 15_L 1.176 0.97
158_C 164_A 1.17 0.97
120_A 134_A 1.161 0.96
109_A 151_P 1.156 0.96
9_Q 164_A 1.152 0.96
165_H 169_R 1.15 0.96
123_T 163_N 1.143 0.96
94_D 128_Y 1.138 0.96
17_V 117_A 1.129 0.96
106_R 144_F 1.124 0.95
48_D 52_K 1.123 0.95
26_P 82_V 1.12 0.95
54_R 58_G 1.111 0.95
120_A 163_N 1.101 0.95
106_R 110_A 1.091 0.94
60_C 66_V 1.09 0.94
61_P 64_H 1.089 0.94
7_V 171_L 1.084 0.94
108_V 116_V 1.082 0.94
107_L 111_N 1.082 0.94
86_W 89_G 1.074 0.94
30_G 39_H 1.071 0.94
7_V 138_V 1.056 0.93
81_T 100_A 1.05 0.93
19_V 79_V 1.05 0.93
24_A 31_G 1.04 0.92
65_A 107_L 1.034 0.92
109_A 148_H 1.034 0.92
36_G 40_R 1.034 0.92
123_T 134_A 1.026 0.92
7_V 158_C 1.022 0.91
144_F 148_H 1.019 0.91
62_T 85_V 1.018 0.91
104_S 118_F 1.017 0.91
158_C 167_Y 1.016 0.91
130_R 160_D 1.015 0.91
105_L 144_F 1.013 0.91
18_D 113_Y 1.012 0.91
31_G 36_G 1.008 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1spvA111000.163Contact Map0.764
4d86A111000.167Contact Map0.705
1yd9A40.98871000.181Contact Map0.831
2xd7A40.97181000.183Contact Map0.681
4iqyA20.97741000.187Contact Map0.827
3q6zA10.99441000.189Contact Map0.707
2x47A10.97741000.191Contact Map0.755
3q71A10.99441000.193Contact Map0.691
1vhuA10.98871000.219Contact Map0.581
4ablA10.91531000.22Contact Map0.608
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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