| UniProt: | P0A884 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11002 | ||
| Length: | 264 (264) | ||
| Sequences: | 1320 | ||
| Seq/Len: | 5.00 |
| TYSY
Paralog alert: 0.03 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 11_V | 170_V | 4.473 | 1.00 | |
| 225_R | 254_P | 4.26 | 1.00 | |
| 10_K | 14_E | 3.82 | 1.00 | |
| 238_S | 241_D | 3.418 | 1.00 | |
| 225_R | 253_D | 3.346 | 1.00 | |
| 63_L | 112_I | 3.096 | 1.00 | |
| 10_K | 32_H | 2.927 | 1.00 | |
| 17_Q | 27_L | 2.867 | 1.00 | |
| 117_N | 121_N | 2.742 | 1.00 | |
| 9_Q | 13_D | 2.666 | 1.00 | |
| 218_L | 221_S | 2.663 | 1.00 | |
| 203_G | 206_T | 2.641 | 1.00 | |
| 208_L | 216_T | 2.583 | 1.00 | |
| 69_I | 73_H | 2.545 | 1.00 | |
| 70_A | 74_E | 2.538 | 1.00 | |
| 115_V | 128_I | 2.509 | 1.00 | |
| 186_H | 196_V | 2.505 | 1.00 | |
| 118_Q | 128_I | 2.489 | 1.00 | |
| 161_C | 185_V | 2.438 | 1.00 | |
| 231_I | 248_E | 2.427 | 1.00 | |
| 231_I | 250_E | 2.427 | 1.00 | |
| 116_L | 188_M | 2.426 | 1.00 | |
| 51_H | 54_S | 2.373 | 1.00 | |
| 186_H | 230_L | 2.335 | 1.00 | |
| 10_K | 29_I | 2.296 | 1.00 | |
| 37_N | 40_D | 2.292 | 1.00 | |
| 19_N | 124_D | 2.25 | 1.00 | |
| 78_T | 81_D | 2.24 | 1.00 | |
| 229_K | 251_G | 2.208 | 1.00 | |
| 52_L | 56_I | 2.174 | 1.00 | |
| 18_K | 124_D | 2.164 | 1.00 | |
| 119_L | 192_C | 2.116 | 1.00 | |
| 27_L | 213_M | 2.109 | 1.00 | |
| 116_L | 239_I | 2.095 | 1.00 | |
| 225_R | 255_H | 2.053 | 1.00 | |
| 191_Q | 242_Y | 1.996 | 1.00 | |
| 53_R | 76_N | 1.981 | 1.00 | |
| 12_L | 217_H | 1.957 | 1.00 | |
| 232_I | 247_F | 1.946 | 1.00 | |
| 67_T | 96_K | 1.913 | 1.00 | |
| 56_I | 247_F | 1.877 | 1.00 | |
| 17_Q | 210_S | 1.869 | 1.00 | |
| 119_L | 128_I | 1.861 | 1.00 | |
| 103_T | 107_R | 1.832 | 1.00 | |
| 73_H | 78_T | 1.781 | 1.00 | |
| 20_D | 25_G | 1.761 | 1.00 | |
| 57_H | 75_N | 1.707 | 1.00 | |
| 201_W | 206_T | 1.698 | 1.00 | |
| 223_E | 255_H | 1.66 | 0.99 | |
| 168_C | 174_L | 1.647 | 0.99 | |
| 39_Q | 158_K | 1.644 | 0.99 | |
| 130_V | 150_F | 1.637 | 0.99 | |
| 16_T | 156_D | 1.63 | 0.99 | |
| 17_Q | 213_M | 1.596 | 0.99 | |
| 99_R | 110_D | 1.588 | 0.99 | |
| 52_L | 249_I | 1.58 | 0.99 | |
| 96_K | 102_P | 1.57 | 0.99 | |
| 236_P | 242_Y | 1.524 | 0.99 | |
| 233_K | 248_E | 1.518 | 0.99 | |
| 115_V | 188_M | 1.517 | 0.99 | |
| 8_M | 216_T | 1.51 | 0.99 | |
| 44_L | 50_C | 1.509 | 0.99 | |
| 35_R | 198_D | 1.483 | 0.98 | |
| 50_C | 55_I | 1.47 | 0.98 | |
| 113_T | 117_N | 1.466 | 0.98 | |
| 138_L | 144_A | 1.464 | 0.98 | |
| 57_H | 77_V | 1.443 | 0.98 | |
| 229_K | 250_E | 1.439 | 0.98 | |
| 44_L | 249_I | 1.437 | 0.98 | |
| 57_H | 71_Y | 1.409 | 0.98 | |
| 158_K | 195_E | 1.403 | 0.97 | |
| 28_S | 153_Y | 1.402 | 0.97 | |
| 170_V | 206_T | 1.401 | 0.97 | |
| 157_G | 194_L | 1.393 | 0.97 | |
| 27_L | 210_S | 1.386 | 0.97 | |
| 191_Q | 236_P | 1.384 | 0.97 | |
| 70_A | 73_H | 1.374 | 0.97 | |
| 230_L | 249_I | 1.346 | 0.96 | |
| 114_T | 118_Q | 1.341 | 0.96 | |
| 233_K | 246_D | 1.326 | 0.96 | |
| 116_L | 192_C | 1.317 | 0.96 | |
| 33_Q | 202_T | 1.291 | 0.95 | |
| 118_Q | 122_D | 1.284 | 0.95 | |
| 29_I | 32_H | 1.276 | 0.95 | |
| 152_F | 161_C | 1.273 | 0.95 | |
| 163_L | 199_F | 1.27 | 0.95 | |
| 73_H | 81_D | 1.258 | 0.94 | |
| 230_L | 247_F | 1.253 | 0.94 | |
| 152_F | 188_M | 1.245 | 0.94 | |
| 9_Q | 217_H | 1.225 | 0.93 | |
| 50_C | 257_G | 1.222 | 0.93 | |
| 5_L | 224_P | 1.221 | 0.93 | |
| 114_T | 139_D | 1.2 | 0.92 | |
| 83_W | 262_V | 1.197 | 0.92 | |
| 115_V | 118_Q | 1.197 | 0.92 | |
| 137_E | 140_K | 1.184 | 0.92 | |
| 100_A | 108_H | 1.182 | 0.91 | |
| 8_M | 170_V | 1.166 | 0.91 | |
| 2_K | 6_E | 1.165 | 0.91 | |
| 234_R | 237_E | 1.135 | 0.89 | |
| 102_P | 107_R | 1.116 | 0.88 | |
| 8_M | 208_L | 1.115 | 0.88 | |
| 96_K | 137_E | 1.113 | 0.88 | |
| 238_S | 242_Y | 1.103 | 0.87 | |
| 71_Y | 75_N | 1.1 | 0.87 | |
| 24_T | 263_A | 1.094 | 0.87 | |
| 115_V | 130_V | 1.09 | 0.86 | |
| 214_D | 217_H | 1.09 | 0.86 | |
| 57_H | 244_F | 1.087 | 0.86 | |
| 66_D | 71_Y | 1.086 | 0.86 | |
| 1_M | 227_L | 1.085 | 0.86 | |
| 96_K | 108_H | 1.076 | 0.85 | |
| 12_L | 208_L | 1.074 | 0.85 | |
| 253_D | 256_P | 1.067 | 0.85 | |
| 101_W | 135_V | 1.065 | 0.85 | |
| 16_T | 155_A | 1.061 | 0.84 | |
| 14_E | 29_I | 1.057 | 0.84 | |
| 102_P | 108_H | 1.05 | 0.83 | |
| 233_K | 237_E | 1.041 | 0.83 | |
| 12_L | 213_M | 1.03 | 0.82 | |
| 27_L | 217_H | 1.028 | 0.82 | |
| 168_C | 201_W | 1.016 | 0.81 | |
| 186_H | 249_I | 1.005 | 0.80 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3v8hA | 4 | 1 | 100 | -0.023 | Contact Map | 0.763 |
| 4dq1A | 2 | 0.9962 | 100 | -0.023 | Contact Map | 0.826 |
| 3uwlA | 2 | 1 | 100 | -0.022 | Contact Map | 0.742 |
| 3nrrA | 2 | 1 | 100 | -0.018 | Contact Map | 0.818 |
| 1hw4A | 1 | 1 | 100 | -0.014 | Contact Map | 0.748 |
| 4ez8A | 1 | 1 | 100 | -0.014 | Contact Map | 0.771 |
| 3hj3A | 4 | 1 | 100 | -0.014 | Contact Map | 0.834 |
| 4g9uA | 4 | 1 | 100 | -0.013 | Contact Map | 0.83 |
| 4eilA | 8 | 1 | 100 | -0.011 | Contact Map | 0.808 |
| 3qg2A | 2 | 1 | 100 | -0.009 | Contact Map | 0.798 |
Sequence Conservation (Image Generated using WebLogo v3)