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OPENSEQ.org

RS2 - 30S ribosomal protein S2
UniProt: P0A7V0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10901
Length: 241 (229)
Sequences: 1358
Seq/Len: 5.93

RS2
Paralog alert: 0.02 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
81_K 85_L 3.715 1.00
65_G 159_D 3.246 1.00
186_I 202_G 3.115 1.00
118_E 152_K 2.871 1.00
113_R 140_E 2.686 1.00
92_V 100_M 2.659 1.00
220_T 224_G 2.653 1.00
56_E 184_F 2.572 1.00
49_M 52_E 2.465 1.00
60_I 160_A 2.293 1.00
14_V 202_G 2.276 1.00
31_I 189_T 2.248 1.00
83_A 86_S 2.242 1.00
163_V 183_V 2.24 1.00
83_A 215_G 2.225 1.00
161_L 176_A 2.131 1.00
87_C 221_V 2.112 1.00
61_A 67_I 2.099 1.00
57_L 217_V 1.932 1.00
57_L 184_F 1.905 1.00
186_I 213_Y 1.892 1.00
121_S 141_L 1.888 1.00
86_S 219_A 1.888 1.00
60_I 65_G 1.881 1.00
162_F 217_V 1.868 1.00
160_A 184_F 1.856 1.00
121_S 126_F 1.823 1.00
121_S 138_T 1.794 1.00
141_L 145_E 1.713 1.00
145_E 149_G 1.711 1.00
119_T 123_D 1.703 1.00
56_E 160_A 1.696 1.00
126_F 134_A 1.683 1.00
26_K 194_D 1.679 1.00
115_K 153_D 1.637 1.00
118_E 141_L 1.635 1.00
58_N 223_E 1.569 0.99
59_K 63_R 1.566 0.99
41_I 189_T 1.531 0.99
187_V 199_V 1.529 0.99
177_N 195_G 1.528 0.99
23_W 39_H 1.511 0.99
42_N 45_K 1.486 0.99
24_N 192_D 1.468 0.99
13_G 16_F 1.451 0.99
117_L 137_R 1.438 0.99
105_K 109_Q 1.389 0.98
86_S 222_R 1.378 0.98
79_A 83_A 1.376 0.98
60_I 184_F 1.373 0.98
177_N 197_D 1.371 0.98
164_I 186_I 1.37 0.98
66_K 90_F 1.366 0.98
50_F 216_A 1.361 0.98
138_T 141_L 1.352 0.98
9_M 14_V 1.337 0.97
4_V 50_F 1.327 0.97
187_V 196_V 1.319 0.97
56_E 60_I 1.296 0.97
67_I 160_A 1.286 0.96
76_A 210_V 1.282 0.96
120_Q 124_G 1.281 0.96
135_L 139_R 1.274 0.96
115_K 152_K 1.257 0.96
154_M 157_L 1.25 0.96
86_S 218_A 1.226 0.95
136_M 139_R 1.224 0.95
8_D 11_K 1.207 0.94
173_I 196_V 1.204 0.94
130_T 135_L 1.2 0.94
97_L 106_T 1.197 0.94
54_L 220_T 1.19 0.94
180_G 183_V 1.189 0.94
157_L 181_I 1.183 0.94
94_H 146_N 1.183 0.94
124_G 127_D 1.166 0.93
87_C 222_R 1.162 0.93
126_F 129_L 1.157 0.93
129_L 137_R 1.155 0.93
97_L 100_M 1.155 0.93
119_T 122_Q 1.148 0.92
215_G 219_A 1.147 0.92
216_A 219_A 1.146 0.92
66_K 159_D 1.138 0.92
213_Y 217_V 1.13 0.91
58_N 224_G 1.129 0.91
14_V 209_A 1.112 0.91
185_A 196_V 1.111 0.91
26_K 192_D 1.11 0.91
138_T 142_E 1.109 0.90
174_K 177_N 1.099 0.90
202_G 209_A 1.099 0.90
4_V 216_A 1.089 0.89
127_D 134_A 1.082 0.89
107_V 151_I 1.082 0.89
55_A 58_N 1.079 0.89
211_T 215_G 1.068 0.88
167_D 191_S 1.046 0.87
170_H 174_K 1.041 0.86
112_K 116_D 1.039 0.86
81_K 93_N 1.031 0.86
117_L 141_L 1.02 0.85
121_S 124_G 1.02 0.85
24_N 194_D 1.016 0.84
129_L 134_A 1.013 0.84
173_I 177_N 1.011 0.84
177_N 183_V 1.01 0.84
28_K 39_H 1.008 0.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kiyB111000.104Contact Map0.6
2vqeB111000.112Contact Map0.695
3bbnB10.95851000.126Contact Map0.531
3zeyC10.79671000.328Contact Map0.486
3u5cA10.79671000.331Contact Map0.542
3j38A10.79671000.334Contact Map0.628
4bpeB10.79671000.336Contact Map0.566
3iz6A10.79671000.34Contact Map0.471
3bchA10.79671000.343Contact Map0.641
3j20B10.78421000.348Contact Map0.583

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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