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OPENSEQ.org

RS18 - 30S ribosomal protein S18
UniProt: P0A7T7 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10917
Length: 75 (73)
Sequences: 846
Seq/Len: 11.59

RS18
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
48_R 51_Y 3.729 1.00
64_Y 70_Y 3.289 1.00
14_T 48_R 3.229 1.00
14_T 51_Y 2.949 1.00
11_C 14_T 2.555 1.00
33_I 68_L 2.45 1.00
11_C 51_Y 2.334 1.00
12_R 47_T 1.889 1.00
47_T 55_L 1.887 1.00
11_C 48_R 1.854 1.00
39_I 59_I 1.752 1.00
12_R 16_E 1.689 1.00
21_I 58_A 1.676 1.00
26_I 67_L 1.651 1.00
21_I 55_L 1.554 1.00
18_V 28_T 1.478 1.00
49_A 53_R 1.477 1.00
18_V 54_Q 1.423 1.00
25_D 28_T 1.359 0.99
22_D 61_R 1.236 0.98
12_R 31_N 1.228 0.98
22_D 58_A 1.188 0.98
14_T 19_Q 1.167 0.97
27_A 30_K 1.141 0.97
13_F 51_Y 1.124 0.97
21_I 65_L 1.092 0.96
36_S 48_R 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kiyR111000.105Contact Map0.705
2vqeR10.986799.90.158Contact Map0.513
3bbnR10.973399.90.203Contact Map0.661
4geqE20.333360.924Contact Map1
2xzfA10.49335.80.924Contact Map0.733
3h0gA20.85334.70.928Contact Map0.326
3u6pA10.484.50.928Contact Map0.762
1k82A40.484.40.929Contact Map0.762
1k3xA10.484.10.93Contact Map0.762
1twfA10.85333.50.932Contact Map0.412

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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