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OPENSEQ.org

RS16 - 30S ribosomal protein S16
UniProt: P0A7T3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10915
Length: 82 (79)
Sequences: 1418
Seq/Len: 17.95

RS16
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
59_H 63_Q 4.196 1.00
56_R 59_H 3.728 1.00
36_V 57_I 3 1.00
40_N 43_A 2.632 1.00
4_I 21_V 2.321 1.00
67_I 75_I 2.17 1.00
34_E 56_R 2.007 1.00
7_A 35_R 1.966 1.00
21_V 36_V 1.9 1.00
54_L 58_A 1.837 1.00
3_T 68_S 1.803 1.00
38_F 51_R 1.794 1.00
11_A 14_R 1.723 1.00
43_A 49_G 1.678 1.00
22_A 26_N 1.578 1.00
22_A 32_F 1.517 1.00
69_D 72_A 1.505 1.00
16_F 38_F 1.498 1.00
2_V 21_V 1.488 1.00
18_Q 35_R 1.442 1.00
27_A 32_F 1.425 1.00
58_A 62_G 1.372 0.99
57_I 75_I 1.362 0.99
59_H 62_G 1.357 0.99
52_L 57_I 1.344 0.99
9_H 18_Q 1.341 0.99
70_R 73_A 1.288 0.99
19_V 52_L 1.282 0.99
2_V 33_I 1.262 0.99
56_R 63_Q 1.261 0.99
53_D 56_R 1.259 0.99
61_V 67_I 1.256 0.99
21_V 33_I 1.23 0.98
40_N 49_G 1.195 0.98
32_F 35_R 1.157 0.97
14_R 42_I 1.151 0.97
72_A 76_K 1.12 0.96
19_V 74_L 1.099 0.96
73_A 77_E 1.098 0.96
73_A 76_K 1.093 0.96
3_T 24_S 1.065 0.95
26_N 31_R 1.054 0.95
27_A 30_G 1.031 0.94
52_L 74_L 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kiyP11100-0.001Contact Map0.721
4juwP10.98781000.02Contact Map0.806
3bbnP10.95121000.024Contact Map0.509
3bn0A10.96341000.025Contact Map0.793
4f11A10.76839.70.92Contact Map0.492
4a17V10.98788.40.922Contact Map0.184
3ks9A20.71958.30.922Contact Map0.645
3zf7w10.98788.10.923Contact Map0.229
2xq0A10.63417.50.924Contact Map0.182
2b78A10.98787.20.924Contact Map0.123

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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