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RL35 - 50S ribosomal protein L35
UniProt: P0A7Q1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11231
Length: 65 (65)
Sequences: 1122
Seq/Len: 17.26

RL35
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
8_R 11_A 3.958 1.00
32_I 35_K 2.831 1.00
26_H 48_A 2.222 1.00
10_A 14_F 2.162 1.00
29_L 45_R 1.935 1.00
51_S 54_D 1.93 1.00
54_D 57_L 1.855 1.00
23_K 49_M 1.823 1.00
16_K 22_F 1.814 1.00
24_H 50_V 1.797 1.00
52_K 55_L 1.659 1.00
40_R 44_L 1.659 1.00
7_V 61_C 1.652 1.00
21_G 49_M 1.537 1.00
50_V 58_V 1.465 1.00
7_V 10_A 1.409 1.00
38_T 41_K 1.398 0.99
37_A 40_R 1.366 0.99
32_I 36_K 1.337 0.99
4_I 63_P 1.31 0.99
28_N 40_R 1.281 0.99
39_K 43_H 1.274 0.99
23_K 47_K 1.252 0.99
42_R 45_R 1.229 0.98
24_H 48_A 1.227 0.98
33_L 41_K 1.214 0.98
22_F 58_V 1.176 0.98
22_F 59_I 1.154 0.97
62_L 65_A 1.122 0.97
17_T 21_G 1.104 0.96
38_T 42_R 1.099 0.96
25_K 29_L 1.086 0.96
10_A 61_C 1.077 0.95
37_A 41_K 1.062 0.95
54_D 58_V 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kix31199.9-0.026Contact Map0.905
3v2d81199.9-0.026Contact Map0.793
2zjr31199.9-0.025Contact Map0.057
3bbo51199.8-0.01Contact Map0.348
3sp4A20.338530.902Contact Map0.634
3ivrA20.63082.80.904Contact Map
4lgcA10.55382.50.907Contact Map
3e7wA10.63082.40.907Contact Map0.843
3g7sA20.61542.30.908Contact Map0.216
3c5eA10.63082.10.91Contact Map0.927

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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