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OPENSEQ.org

RL27 - 50S ribosomal protein L27
UniProt: P0A7L8 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG50002
Length: 85 (84)
Sequences: 1185
Seq/Len: 14.11

RL27
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
32_L 35_S 3.327 1.00
25_R 31_V 3.234 1.00
53_C 57_H 3.221 1.00
21_L 41_R 2.869 1.00
52_G 62_K 2.702 1.00
23_V 38_V 2.653 1.00
25_R 35_S 2.363 1.00
68_K 83_E 2.164 1.00
70_E 81_S 1.845 1.00
30_S 66_K 1.828 1.00
25_R 29_E 1.816 1.00
52_G 60_F 1.784 1.00
51_V 59_L 1.764 1.00
63_A 84_A 1.761 1.00
46_H 77_R 1.637 1.00
70_E 83_E 1.637 1.00
43_T 53_C 1.633 1.00
38_V 45_F 1.613 1.00
17_E 20_R 1.59 1.00
45_F 80_I 1.554 1.00
45_F 78_K 1.492 1.00
72_K 79_F 1.467 1.00
54_G 58_T 1.461 1.00
33_A 64_D 1.448 1.00
25_R 67_V 1.338 0.99
44_K 78_K 1.299 0.99
32_L 64_D 1.253 0.99
50_N 63_A 1.245 0.98
1_M 27_G 1.232 0.98
23_V 26_F 1.216 0.98
71_V 78_K 1.205 0.98
37_I 59_L 1.183 0.98
53_C 59_L 1.161 0.97
7_G 10_T 1.137 0.97
71_V 79_F 1.124 0.97
39_R 56_D 1.123 0.97
73_G 76_N 1.1 0.96
41_R 57_H 1.09 0.96
31_V 37_I 1.085 0.96
70_E 79_F 1.042 0.94
43_T 57_H 1.038 0.94
30_S 64_D 1.034 0.94
68_K 81_S 1.019 0.93
49_A 83_E 1 0.92
23_V 69_F 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3bboX10.9882100-0.028Contact Map0.082
4kixW11100-0.02Contact Map0.326
3v2d010.9882100-0.013Contact Map0.837
1pnuU10.97651000.012Contact Map0
2ftcO10.81000.122Contact Map0
4ifdG10.705979.20.875Contact Map0.766
2ba0A30.5765740.881Contact Map0.839
2nn6G10.952972.20.882Contact Map0.535
2nn6I10.8471700.884Contact Map0.604
4ifdI10.870657.10.893Contact Map0.588

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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