| UniProt: | P0A7D1 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10785 | ||
| Length: | 194 (189) | ||
| Sequences: | 1953 | ||
| Seq/Len: | 10.33 |
| PTH
Paralog alert: 0.03 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 96_L | 137_I | 3.516 | 1.00 | |
| 76_A | 80_S | 3.198 | 1.00 | |
| 121_I | 130_F | 3.174 | 1.00 | |
| 79_A | 89_I | 2.987 | 1.00 | |
| 47_G | 62_L | 2.956 | 1.00 | |
| 75_V | 120_I | 2.813 | 1.00 | |
| 29_D | 63_V | 2.809 | 1.00 | |
| 4_K | 88_E | 2.791 | 1.00 | |
| 93_H | 117_L | 2.721 | 1.00 | |
| 19_T | 153_K | 2.703 | 1.00 | |
| 51_R | 58_D | 2.534 | 1.00 | |
| 70_L | 73_K | 2.469 | 1.00 | |
| 30_L | 33_E | 2.416 | 1.00 | |
| 37_A | 50_S | 2.413 | 1.00 | |
| 115_N | 118_K | 2.305 | 1.00 | |
| 62_L | 78_M | 2.175 | 1.00 | |
| 46_F | 73_K | 2.119 | 1.00 | |
| 7_V | 75_V | 2.044 | 1.00 | |
| 96_L | 146_V | 1.973 | 1.00 | |
| 14_A | 17_A | 1.87 | 1.00 | |
| 34_R | 171_R | 1.86 | 1.00 | |
| 37_A | 52_V | 1.841 | 1.00 | |
| 90_L | 133_L | 1.833 | 1.00 | |
| 32_A | 61_L | 1.81 | 1.00 | |
| 47_G | 74_A | 1.796 | 1.00 | |
| 34_R | 174_E | 1.753 | 1.00 | |
| 111_H | 118_K | 1.711 | 1.00 | |
| 39_L | 50_S | 1.675 | 1.00 | |
| 27_F | 166_I | 1.666 | 1.00 | |
| 28_V | 61_L | 1.663 | 1.00 | |
| 91_V | 120_I | 1.661 | 1.00 | |
| 28_V | 39_L | 1.644 | 1.00 | |
| 111_H | 121_I | 1.621 | 1.00 | |
| 25_A | 63_V | 1.592 | 1.00 | |
| 119_D | 123_K | 1.587 | 1.00 | |
| 175_M | 184_A | 1.584 | 1.00 | |
| 62_L | 74_A | 1.581 | 1.00 | |
| 66_T | 74_A | 1.58 | 1.00 | |
| 48_Y | 65_T | 1.485 | 1.00 | |
| 180_G | 184_A | 1.481 | 1.00 | |
| 5_L | 84_I | 1.46 | 1.00 | |
| 18_A | 26_W | 1.448 | 1.00 | |
| 27_F | 92_A | 1.437 | 1.00 | |
| 76_A | 123_K | 1.399 | 0.99 | |
| 30_L | 167_D | 1.398 | 0.99 | |
| 79_A | 124_L | 1.395 | 0.99 | |
| 39_L | 63_V | 1.39 | 0.99 | |
| 23_A | 135_I | 1.385 | 0.99 | |
| 20_R | 158_E | 1.383 | 0.99 | |
| 27_F | 169_A | 1.37 | 0.99 | |
| 105_F | 133_L | 1.355 | 0.99 | |
| 95_E | 112_G | 1.33 | 0.99 | |
| 100_P | 165_A | 1.309 | 0.99 | |
| 26_W | 154_P | 1.308 | 0.99 | |
| 147_V | 152_G | 1.3 | 0.99 | |
| 85_N | 88_E | 1.294 | 0.99 | |
| 107_L | 182_T | 1.294 | 0.99 | |
| 139_H | 146_V | 1.263 | 0.99 | |
| 131_H | 181_L | 1.22 | 0.98 | |
| 145_K | 148_G | 1.199 | 0.98 | |
| 90_L | 176_W | 1.191 | 0.98 | |
| 32_A | 37_A | 1.19 | 0.98 | |
| 175_M | 188_L | 1.18 | 0.98 | |
| 100_P | 138_G | 1.174 | 0.98 | |
| 141_G | 144_N | 1.172 | 0.98 | |
| 117_L | 130_F | 1.164 | 0.97 | |
| 31_L | 173_T | 1.149 | 0.97 | |
| 159_Q | 163_D | 1.14 | 0.97 | |
| 30_L | 170_A | 1.137 | 0.97 | |
| 175_M | 179_D | 1.124 | 0.97 | |
| 157_S | 160_K | 1.12 | 0.96 | |
| 119_D | 122_S | 1.118 | 0.96 | |
| 34_R | 170_A | 1.114 | 0.96 | |
| 180_G | 183_K | 1.112 | 0.96 | |
| 107_L | 131_H | 1.106 | 0.96 | |
| 86_P | 126_N | 1.101 | 0.96 | |
| 140_P | 146_V | 1.09 | 0.96 | |
| 156_V | 160_K | 1.088 | 0.96 | |
| 79_A | 84_I | 1.072 | 0.95 | |
| 6_I | 92_A | 1.07 | 0.95 | |
| 25_A | 64_P | 1.067 | 0.95 | |
| 179_D | 183_K | 1.06 | 0.95 | |
| 172_C | 188_L | 1.044 | 0.94 | |
| 183_K | 187_R | 1.039 | 0.94 | |
| 100_P | 162_I | 1.037 | 0.94 | |
| 26_W | 162_I | 1.034 | 0.94 | |
| 68_M | 114_H | 1.025 | 0.93 | |
| 135_I | 165_A | 1.022 | 0.93 | |
| 161_L | 164_E | 1.021 | 0.93 | |
| 160_K | 164_E | 1.016 | 0.93 | |
| 133_L | 176_W | 1.014 | 0.93 | |
| 171_R | 187_R | 1.013 | 0.93 | |
| 160_K | 163_D | 1.012 | 0.93 | |
| 20_R | 152_G | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2pthA | 1 | 0.9897 | 100 | -0.001 | Contact Map | 0.79 |
| 3v2iA | 1 | 0.9897 | 100 | 0 | Contact Map | 0.843 |
| 2z2iA | 1 | 0.9794 | 100 | 0.006 | Contact Map | 0.776 |
| 4lwrA | 1 | 0.9897 | 100 | 0.007 | Contact Map | 0.781 |
| 4jx9A | 1 | 0.9897 | 100 | 0.008 | Contact Map | 0.783 |
| 3neaA | 1 | 0.9639 | 100 | 0.009 | Contact Map | 0.756 |
| 4fyjA | 1 | 0.9897 | 100 | 0.014 | Contact Map | 0.756 |
| 1rybA | 1 | 0.9794 | 100 | 0.018 | Contact Map | 0.781 |
| 2yfaA | 2 | 0.4433 | 27.8 | 0.953 | Contact Map | 0.425 |
| 1c8bA | 2 | 0.8814 | 22.7 | 0.955 | Contact Map | 0.142 |
Sequence Conservation (Image Generated using WebLogo v3)