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OPENSEQ.org

PAND - Aspartate 1-decarboxylase
UniProt: P0A790 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11747
Length: 126 (123)
Sequences: 823
Seq/Len: 6.69

PAND
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
38_I 59_A 4.169 1.00
45_D 56_S 3.149 1.00
53_K 78_C 2.962 1.00
31_D 65_G 2.923 1.00
47_W 88_A 2.669 1.00
30_Q 61_A 2.606 1.00
34_D 64_R 2.568 1.00
30_Q 64_R 2.287 1.00
109_E 113_E 2.155 1.00
31_D 64_R 2.133 1.00
93_M 98_A 2.11 1.00
35_A 114_M 2.107 1.00
28_I 69_I 2.043 1.00
27_A 62_A 2.014 1.00
10_L 108_F 2.004 1.00
33_L 59_A 1.984 1.00
26_C 46_I 1.961 1.00
69_I 87_I 1.859 1.00
48_N 79_A 1.846 1.00
26_C 44_I 1.845 1.00
2_I 92_T 1.837 1.00
77_H 80_S 1.796 1.00
7_Q 42_E 1.778 1.00
49_V 84_I 1.773 1.00
36_A 106_A 1.693 1.00
50_T 77_H 1.681 1.00
47_W 90_F 1.663 1.00
43_A 56_S 1.65 1.00
31_D 34_D 1.586 1.00
3_R 95_D 1.479 0.99
4_T 43_A 1.458 0.99
17_H 70_S 1.456 0.99
10_L 13_V 1.398 0.99
4_T 92_T 1.382 0.98
6_L 88_A 1.375 0.98
67_R 113_E 1.375 0.98
40_E 61_A 1.363 0.98
55_F 79_A 1.362 0.98
13_V 85_V 1.334 0.98
50_T 84_I 1.327 0.98
32_F 108_F 1.317 0.98
37_G 104_N 1.289 0.97
28_I 87_I 1.285 0.97
28_I 59_A 1.237 0.96
13_V 108_F 1.227 0.96
3_R 37_G 1.221 0.96
38_I 89_S 1.205 0.96
23_E 47_W 1.201 0.95
30_Q 34_D 1.167 0.94
33_L 38_I 1.166 0.94
93_M 97_E 1.109 0.92
95_D 99_R 1.108 0.92
26_C 79_A 1.107 0.92
37_G 95_D 1.098 0.92
98_A 101_W 1.085 0.91
49_V 74_A 1.082 0.91
93_M 101_W 1.031 0.88
8_G 37_G 1.029 0.88
29_D 66_S 1.028 0.88
69_I 85_V 1.016 0.87
48_N 53_K 1.004 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1pqhA21100-0.027Contact Map0.799
2c45A80.9921100-0.008Contact Map0.785
3ougA80.8811000.034Contact Map0.834
1vc3B10.76191000.244Contact Map0.915
3plxB10.80161000.245Contact Map0.731
1uheA10.76981000.276Contact Map0.708
3plxA10.190599.10.781Contact Map1
1vc3A10.190599.10.781Contact Map1
1uheB10.190599.10.781Contact Map1
1cz4A10.920682.40.918Contact Map0.415

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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