| UniProt: | P0A6R0 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10277 | ||
| Length: | 317 (316) | ||
| Sequences: | 4628 | ||
| Seq/Len: | 14.65 |
| FABH
Paralog alert: 0.51 [within 20: 0.07] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 56_F | 97_M | 3.996 | 1.00 | |
| 133_Y | 167_A | 3.718 | 1.00 | |
| 298_L | 316_R | 3.497 | 1.00 | |
| 6_I | 167_A | 3.095 | 1.00 | |
| 34_V | 40_R | 2.961 | 1.00 | |
| 41_E | 271_R | 2.903 | 1.00 | |
| 40_R | 270_D | 2.898 | 1.00 | |
| 10_S | 285_D | 2.862 | 1.00 | |
| 94_I | 137_V | 2.845 | 1.00 | |
| 55_G | 94_I | 2.779 | 1.00 | |
| 75_L | 134_A | 2.682 | 1.00 | |
| 285_D | 289_R | 2.679 | 1.00 | |
| 57_E | 60_T | 2.497 | 1.00 | |
| 56_F | 94_I | 2.484 | 1.00 | |
| 62_A | 165_V | 2.45 | 1.00 | |
| 53_T | 97_M | 2.384 | 1.00 | |
| 3_T | 123_D | 2.308 | 1.00 | |
| 118_A | 136_V | 2.201 | 1.00 | |
| 59_A | 135_L | 2.201 | 1.00 | |
| 234_D | 237_Q | 2.162 | 1.00 | |
| 122_A | 134_A | 2.156 | 1.00 | |
| 11_Y | 54_M | 2.156 | 1.00 | |
| 18_T | 21_D | 2.152 | 1.00 | |
| 8_T | 285_D | 2.141 | 1.00 | |
| 74_G | 133_Y | 2.134 | 1.00 | |
| 239_D | 297_Q | 2.133 | 1.00 | |
| 123_D | 127_K | 2.101 | 1.00 | |
| 119_L | 166_L | 2.089 | 1.00 | |
| 16_V | 41_E | 2.089 | 1.00 | |
| 65_M | 288_V | 2.048 | 1.00 | |
| 261_S | 264_N | 2.036 | 1.00 | |
| 56_F | 60_T | 2.026 | 1.00 | |
| 26_V | 154_I | 1.959 | 1.00 | |
| 72_Q | 133_Y | 1.941 | 1.00 | |
| 20_A | 23_E | 1.934 | 1.00 | |
| 16_V | 43_H | 1.92 | 1.00 | |
| 294_K | 297_Q | 1.909 | 1.00 | |
| 275_T | 282_C | 1.868 | 1.00 | |
| 69_E | 72_Q | 1.864 | 1.00 | |
| 225_D | 229_A | 1.864 | 1.00 | |
| 63_I | 70_K | 1.859 | 1.00 | |
| 18_T | 41_E | 1.787 | 1.00 | |
| 21_D | 24_K | 1.786 | 1.00 | |
| 74_G | 132_K | 1.767 | 1.00 | |
| 126_V | 166_L | 1.757 | 1.00 | |
| 176_S | 231_N | 1.748 | 1.00 | |
| 59_A | 98_L | 1.728 | 1.00 | |
| 51_V | 139_S | 1.726 | 1.00 | |
| 178_H | 230_A | 1.704 | 1.00 | |
| 62_A | 66_A | 1.698 | 1.00 | |
| 12_L | 272_H | 1.698 | 1.00 | |
| 68_I | 133_Y | 1.688 | 1.00 | |
| 79_A | 118_A | 1.687 | 1.00 | |
| 271_R | 286_E | 1.683 | 1.00 | |
| 52_S | 84_T | 1.668 | 1.00 | |
| 248_L | 252_S | 1.666 | 1.00 | |
| 60_T | 64_E | 1.662 | 1.00 | |
| 301_L | 315_V | 1.652 | 1.00 | |
| 255_A | 262_M | 1.651 | 1.00 | |
| 267_V | 270_D | 1.646 | 1.00 | |
| 233_L | 237_Q | 1.644 | 1.00 | |
| 68_I | 165_V | 1.625 | 1.00 | |
| 9_G | 62_A | 1.62 | 1.00 | |
| 77_V | 106_F | 1.6 | 1.00 | |
| 58_A | 163_A | 1.599 | 1.00 | |
| 50_T | 53_T | 1.586 | 1.00 | |
| 77_V | 122_A | 1.554 | 1.00 | |
| 31_E | 35_T | 1.539 | 1.00 | |
| 63_I | 73_I | 1.538 | 1.00 | |
| 44_I | 148_P | 1.534 | 1.00 | |
| 75_L | 125_Y | 1.533 | 1.00 | |
| 17_R | 44_I | 1.499 | 1.00 | |
| 233_L | 298_L | 1.492 | 1.00 | |
| 227_T | 312_S | 1.482 | 1.00 | |
| 7_G | 65_M | 1.481 | 1.00 | |
| 208_A | 211_E | 1.463 | 1.00 | |
| 61_R | 65_M | 1.456 | 1.00 | |
| 61_R | 64_E | 1.447 | 1.00 | |
| 231_N | 314_L | 1.442 | 1.00 | |
| 175_I | 316_R | 1.423 | 1.00 | |
| 251_I | 265_V | 1.422 | 1.00 | |
| 266_V | 283_A | 1.419 | 1.00 | |
| 227_T | 314_L | 1.419 | 1.00 | |
| 68_I | 72_Q | 1.409 | 1.00 | |
| 73_I | 165_V | 1.396 | 0.99 | |
| 45_A | 141_V | 1.393 | 0.99 | |
| 176_S | 227_T | 1.392 | 0.99 | |
| 252_S | 262_M | 1.374 | 0.99 | |
| 9_G | 61_R | 1.362 | 0.99 | |
| 46_A | 49_E | 1.357 | 0.99 | |
| 288_V | 293_I | 1.343 | 0.99 | |
| 73_I | 100_I | 1.343 | 0.99 | |
| 59_A | 137_V | 1.334 | 0.99 | |
| 268_T | 286_E | 1.332 | 0.99 | |
| 115_F | 281_P | 1.321 | 0.99 | |
| 65_M | 289_R | 1.312 | 0.99 | |
| 124_Q | 128_S | 1.31 | 0.99 | |
| 57_E | 61_R | 1.306 | 0.99 | |
| 100_I | 103_C | 1.305 | 0.99 | |
| 239_D | 298_L | 1.3 | 0.99 | |
| 122_A | 166_L | 1.298 | 0.99 | |
| 115_F | 164_A | 1.288 | 0.99 | |
| 178_H | 226_E | 1.287 | 0.99 | |
| 240_W | 297_Q | 1.283 | 0.99 | |
| 126_V | 134_A | 1.282 | 0.99 | |
| 72_Q | 132_K | 1.276 | 0.99 | |
| 55_G | 139_S | 1.271 | 0.99 | |
| 113_A | 309_T | 1.269 | 0.99 | |
| 78_V | 90_A | 1.257 | 0.99 | |
| 225_D | 235_R | 1.257 | 0.99 | |
| 173_G | 316_R | 1.255 | 0.99 | |
| 295_P | 317_F | 1.252 | 0.99 | |
| 223_I | 312_S | 1.251 | 0.99 | |
| 176_S | 230_A | 1.231 | 0.98 | |
| 139_S | 161_A | 1.226 | 0.98 | |
| 60_T | 70_K | 1.22 | 0.98 | |
| 106_F | 121_V | 1.216 | 0.98 | |
| 63_I | 68_I | 1.212 | 0.98 | |
| 7_G | 165_V | 1.211 | 0.98 | |
| 7_G | 66_A | 1.209 | 0.98 | |
| 30_D | 34_V | 1.207 | 0.98 | |
| 248_L | 267_V | 1.207 | 0.98 | |
| 56_F | 98_L | 1.201 | 0.98 | |
| 10_S | 282_C | 1.197 | 0.98 | |
| 240_W | 292_R | 1.175 | 0.98 | |
| 76_I | 100_I | 1.175 | 0.98 | |
| 15_Q | 21_D | 1.171 | 0.98 | |
| 108_V | 121_V | 1.149 | 0.97 | |
| 14_E | 49_E | 1.142 | 0.97 | |
| 74_G | 131_V | 1.139 | 0.97 | |
| 71_D | 101_K | 1.135 | 0.97 | |
| 228_L | 235_R | 1.126 | 0.97 | |
| 238_L | 300_L | 1.126 | 0.97 | |
| 10_S | 289_R | 1.124 | 0.97 | |
| 162_G | 281_P | 1.123 | 0.97 | |
| 141_V | 144_R | 1.118 | 0.96 | |
| 222_H | 226_E | 1.108 | 0.96 | |
| 61_R | 285_D | 1.104 | 0.96 | |
| 244_H | 274_N | 1.085 | 0.96 | |
| 131_V | 134_A | 1.084 | 0.96 | |
| 148_P | 154_I | 1.074 | 0.95 | |
| 70_K | 100_I | 1.074 | 0.95 | |
| 266_V | 287_A | 1.072 | 0.95 | |
| 7_G | 62_A | 1.071 | 0.95 | |
| 52_S | 90_A | 1.064 | 0.95 | |
| 4_K | 169_S | 1.06 | 0.95 | |
| 111_A | 306_G | 1.057 | 0.95 | |
| 242_V | 283_A | 1.056 | 0.95 | |
| 54_M | 141_V | 1.053 | 0.95 | |
| 136_V | 166_L | 1.047 | 0.94 | |
| 76_I | 95_Q | 1.046 | 0.94 | |
| 77_V | 134_A | 1.039 | 0.94 | |
| 226_E | 229_A | 1.038 | 0.94 | |
| 122_A | 136_V | 1.027 | 0.94 | |
| 20_A | 24_K | 1.017 | 0.93 | |
| 81_T | 111_A | 1.008 | 0.93 | |
| 124_Q | 130_A | 1.006 | 0.93 | |
| 178_H | 312_S | 1 | 0.92 | |
| 135_L | 165_V | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3il3A | 1 | 0.9937 | 100 | 0.218 | Contact Map | 0.869 |
| 4ewpA | 6 | 0.9968 | 100 | 0.233 | Contact Map | 0.827 |
| 3gwaA | 2 | 1 | 100 | 0.234 | Contact Map | 0.835 |
| 2f82A | 1 | 0.9558 | 100 | 0.246 | Contact Map | 0.668 |
| 1hnjA | 1 | 0.9968 | 100 | 0.247 | Contact Map | 0.843 |
| 4efiA | 1 | 1 | 100 | 0.248 | Contact Map | 0.728 |
| 4dfeA | 4 | 1 | 100 | 0.25 | Contact Map | 0.872 |
| 3euoA | 2 | 0.9748 | 100 | 0.252 | Contact Map | 0.711 |
| 1zowA | 4 | 0.9779 | 100 | 0.254 | Contact Map | 0.897 |
| 3il6A | 1 | 0.9811 | 100 | 0.257 | Contact Map | 0.83 |
Sequence Conservation (Image Generated using WebLogo v3)