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OPENSEQ.org
UBIB - Probable ubiquinone biosynthesis protein UbiB
UniProt: P0A6A0 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11476
Length: 546 (541)
Sequences: 1185
Seq/Len: 2.19
UBIB
Paralog alert: 0.09 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
124_D 142_R 4.425 1.00
125_F 152_I 3.647 1.00
100_F 105_A 3.583 1.00
258_E 264_M 3.529 1.00
136_A 206_L 3.411 1.00
219_N 282_D 3.237 1.00
295_F 309_I 3.174 1.00
112_A 239_G 3.018 1.00
140_T 245_R 2.96 1.00
265_K 420_Y 2.752 1.00
152_I 240_M 2.743 1.00
106_K 119_E 2.696 1.00
148_K 230_E 2.59 1.00
106_K 110_E 2.577 1.00
109_I 154_V 2.471 1.00
54_G 86_I 2.426 1.00
231_V 243_M 2.386 1.00
145_S 148_K 2.338 1.00
249_I 260_N 2.3 1.00
58_R 89_Q 2.299 1.00
214_I 233_P 2.267 1.00
148_K 232_Y 2.261 1.00
266_L 270_R 2.259 1.00
101_D 104_L 2.251 1.00
233_P 236_C 2.227 1.00
327_E 339_K 2.227 1.00
197_E 201_I 2.157 1.00
253_D 256_A 2.109 0.99
171_Y 197_E 2.102 0.99
232_Y 235_Y 2.085 0.99
271_G 416_G 2.068 0.99
376_A 422_Q 2.029 0.99
123_D 144_K 1.974 0.99
140_T 149_E 1.966 0.99
164_K 201_I 1.964 0.99
102_G 105_A 1.942 0.99
130_L 151_V 1.935 0.99
318_N 321_D 1.885 0.99
151_V 245_R 1.869 0.98
106_K 127_I 1.822 0.98
155_I 206_L 1.82 0.98
277_T 282_D 1.799 0.98
53_L 85_H 1.781 0.98
142_R 149_E 1.779 0.98
277_T 281_R 1.776 0.98
141_A 152_I 1.77 0.98
160_L 164_K 1.76 0.98
210_S 233_P 1.757 0.98
79_R 82_F 1.756 0.97
424_D 427_K 1.738 0.97
181_L 184_G 1.732 0.97
125_F 141_A 1.721 0.97
174_A 193_V 1.712 0.97
115_G 120_A 1.707 0.97
110_E 118_V 1.705 0.97
84_P 88_D 1.703 0.97
76_S 94_Q 1.697 0.97
362_A 394_F 1.682 0.97
113_M 242_V 1.662 0.96
110_E 117_P 1.657 0.96
171_Y 194_R 1.648 0.96
121_W 242_V 1.645 0.96
338_R 360_E 1.639 0.96
213_A 231_V 1.63 0.96
264_M 267_L 1.62 0.95
103_K 127_I 1.615 0.95
122_F 242_V 1.612 0.95
257_L 264_M 1.608 0.95
355_N 358_E 1.598 0.95
109_I 125_F 1.578 0.95
256_A 260_N 1.566 0.94
149_E 247_Y 1.562 0.94
160_L 238_E 1.546 0.94
112_A 237_S 1.544 0.94
287_A 313_I 1.533 0.93
254_V 258_E 1.522 0.93
132_S 425_L 1.514 0.93
19_Y 63_E 1.508 0.93
255_A 258_E 1.503 0.92
71_F 193_V 1.47 0.91
215_Q 316_S 1.466 0.91
228_I 314_V 1.459 0.91
213_A 311_C 1.454 0.91
51_K 55_E 1.452 0.91
89_Q 92_L 1.439 0.90
115_G 121_W 1.438 0.90
62_Q 92_L 1.433 0.90
12_I 64_L 1.433 0.90
254_V 264_M 1.419 0.89
118_V 125_F 1.415 0.89
225_M 270_R 1.411 0.89
502_F 505_I 1.407 0.89
115_G 118_V 1.403 0.89
8_R 12_I 1.394 0.88
60_A 63_E 1.394 0.88
104_L 108_Q 1.389 0.88
509_L 512_S 1.371 0.87
210_S 236_C 1.37 0.87
430_K 434_E 1.361 0.86
102_G 106_K 1.361 0.86
175_R 190_T 1.361 0.86
100_F 156_R 1.355 0.86
496_Q 499_S 1.351 0.86
231_V 241_M 1.351 0.86
265_K 422_Q 1.34 0.85
511_L 518_V 1.337 0.85
435_S 439_D 1.333 0.85
55_E 89_Q 1.333 0.85
117_P 120_A 1.329 0.85
217_R 227_Y 1.321 0.84
317_L 423_L 1.32 0.84
217_R 230_E 1.312 0.84
143_L 235_Y 1.311 0.84
143_L 146_N 1.303 0.83
188_R 191_E 1.296 0.83
82_F 90_L 1.289 0.82
342_E 356_V 1.287 0.82
58_R 92_L 1.287 0.82
359_F 396_M 1.286 0.82
178_P 190_T 1.281 0.82
103_K 222_D 1.268 0.81
338_R 342_E 1.267 0.81
12_I 68_W 1.257 0.80
341_A 363_I 1.252 0.79
207_L 236_C 1.25 0.79
82_F 87_A 1.248 0.79
220_F 271_G 1.244 0.79
15_T 60_A 1.239 0.79
112_A 154_V 1.235 0.78
297_S 305_K 1.214 0.77
269_E 420_Y 1.213 0.76
251_V 296_V 1.211 0.76
297_S 307_I 1.211 0.76
242_V 250_P 1.204 0.76
210_S 241_M 1.2 0.75
268_A 420_Y 1.198 0.75
155_I 239_G 1.191 0.75
167_L 197_E 1.185 0.74
205_N 238_E 1.183 0.74
333_F 433_L 1.182 0.74
227_Y 244_E 1.181 0.74
344_H 406_Q 1.178 0.73
126_E 140_T 1.178 0.73
100_F 132_S 1.174 0.73
262_T 267_L 1.162 0.72
125_F 206_L 1.156 0.71
509_L 532_A 1.156 0.71
121_W 235_Y 1.151 0.71
272_V 423_L 1.15 0.71
423_L 428_T 1.149 0.71
216_L 314_V 1.147 0.71
220_F 284_F 1.138 0.70
528_G 532_A 1.136 0.70
501_Y 504_G 1.136 0.70
323_R 327_E 1.132 0.69
256_A 259_K 1.131 0.69
94_Q 250_P 1.13 0.69
487_R 490_Q 1.125 0.68
192_V 403_V 1.118 0.68
276_F 420_Y 1.114 0.67
340_V 363_I 1.111 0.67
246_I 309_I 1.109 0.67
210_S 214_I 1.108 0.67
510_V 515_F 1.107 0.67
13_I 16_F 1.107 0.67
76_S 278_Q 1.107 0.67
150_V 242_V 1.103 0.66
442_G 445_A 1.102 0.66
344_H 396_M 1.092 0.65
154_V 240_M 1.092 0.65
523_W 528_G 1.091 0.65
120_A 144_K 1.087 0.65
500_R 505_I 1.083 0.64
495_R 506_G 1.083 0.64
196_Y 311_C 1.083 0.64
161_P 438_K 1.075 0.63
58_R 62_Q 1.073 0.63
271_G 329_F 1.068 0.63
281_R 432_F 1.067 0.62
283_S 304_P 1.067 0.62
9_L 172_R 1.066 0.62
71_F 437_I 1.064 0.62
214_I 236_C 1.061 0.62
120_A 128_K 1.059 0.62
313_I 408_T 1.058 0.61
110_E 125_F 1.055 0.61
232_Y 244_E 1.055 0.61
123_D 142_R 1.054 0.61
529_W 537_A 1.053 0.61
178_P 188_R 1.049 0.60
338_R 341_A 1.048 0.60
107_Q 111_A 1.043 0.60
121_W 240_M 1.038 0.59
113_M 121_W 1.038 0.59
501_Y 506_G 1.037 0.59
322_K 391_A 1.037 0.59
375_L 416_G 1.03 0.58
95_D 250_P 1.028 0.58
5_E 9_L 1.026 0.58
66_P 340_V 1.026 0.58
164_K 197_E 1.025 0.58
152_I 242_V 1.025 0.58
57_L 99_P 1.024 0.58
104_L 107_Q 1.023 0.58
510_V 514_T 1.022 0.58
497_G 500_R 1.022 0.58
331_A 340_V 1.02 0.57
501_Y 505_I 1.019 0.57
409_L 425_L 1.019 0.57
69_I 388_F 1.019 0.57
95_D 133_A 1.017 0.57
134_S 203_E 1.017 0.57
219_N 284_F 1.013 0.56
464_L 509_L 1.012 0.56
486_A 490_Q 1.011 0.56
267_L 296_V 1.01 0.56
504_G 509_L 1.01 0.56
194_R 197_E 1.009 0.56
495_R 504_G 1.006 0.56
529_W 533_G 1.006 0.56
108_Q 111_A 1.004 0.55
75_L 82_F 1.003 0.55
151_V 460_K 1.002 0.55
500_R 509_L 1 0.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2y7jA40.45051000.755Contact Map0.398
3byvA10.57141000.757Contact Map0.29
2acxA20.72711000.79Contact Map0.332
4gyiA10.55861000.792Contact Map0.396
3v5wA10.72341000.832Contact Map0.296
1u5qA20.529399.90.846Contact Map0.453
1zarA10.450599.90.85Contact Map0.48
3dzoA10.567899.90.855Contact Map0.337
2c30A10.496399.90.869Contact Map0.435
3fegA10.51199.80.873Contact Map0.275
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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