| UniProt: | P06966 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10226 | ||
| Length: | 135 (117) | ||
| Sequences: | 785 | ||
| Seq/Len: | 6.71 |
| DICA
Paralog alert: 0.39 [within 20: 0.03] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 16_R | 41_E | 2.91 | 1.00 | |
| 24_R | 28_K | 2.678 | 1.00 | |
| 30_L | 58_V | 2.397 | 1.00 | |
| 26_L | 37_V | 2.272 | 1.00 | |
| 8_I | 12_I | 2.209 | 1.00 | |
| 15_R | 59_L | 2.191 | 1.00 | |
| 21_H | 26_L | 2.116 | 1.00 | |
| 57_K | 69_G | 2.096 | 1.00 | |
| 30_L | 59_L | 1.957 | 1.00 | |
| 32_I | 37_V | 1.868 | 1.00 | |
| 24_R | 34_H | 1.864 | 1.00 | |
| 21_H | 58_V | 1.805 | 1.00 | |
| 63_P | 67_L | 1.761 | 1.00 | |
| 33_S | 36_S | 1.697 | 1.00 | |
| 15_R | 61_C | 1.651 | 1.00 | |
| 9_G | 43_G | 1.6 | 1.00 | |
| 25_S | 28_K | 1.564 | 0.99 | |
| 36_S | 40_W | 1.553 | 0.99 | |
| 40_W | 47_P | 1.535 | 0.99 | |
| 9_G | 41_E | 1.513 | 0.99 | |
| 40_W | 55_L | 1.497 | 0.99 | |
| 100_P | 103_E | 1.493 | 0.99 | |
| 21_H | 29_A | 1.418 | 0.99 | |
| 39_Q | 44_D | 1.384 | 0.98 | |
| 16_R | 23_Q | 1.353 | 0.98 | |
| 112_R | 116_K | 1.343 | 0.98 | |
| 39_Q | 45_S | 1.323 | 0.98 | |
| 35_V | 39_Q | 1.303 | 0.98 | |
| 86_S | 104_Q | 1.302 | 0.97 | |
| 34_H | 38_S | 1.294 | 0.97 | |
| 11_R | 68_F | 1.283 | 0.97 | |
| 25_S | 29_A | 1.266 | 0.97 | |
| 26_L | 59_L | 1.256 | 0.97 | |
| 23_Q | 41_E | 1.236 | 0.96 | |
| 11_R | 65_W | 1.232 | 0.96 | |
| 9_G | 16_R | 1.216 | 0.96 | |
| 26_L | 55_L | 1.196 | 0.95 | |
| 96_F | 99_L | 1.189 | 0.95 | |
| 100_P | 106_T | 1.159 | 0.94 | |
| 64_T | 69_G | 1.157 | 0.94 | |
| 7_T | 43_G | 1.15 | 0.94 | |
| 51_N | 54_A | 1.135 | 0.93 | |
| 35_V | 38_S | 1.126 | 0.93 | |
| 99_L | 104_Q | 1.126 | 0.93 | |
| 12_I | 26_L | 1.12 | 0.93 | |
| 24_R | 27_A | 1.106 | 0.92 | |
| 27_A | 34_H | 1.087 | 0.91 | |
| 103_E | 107_Q | 1.082 | 0.91 | |
| 38_S | 42_R | 1.074 | 0.91 | |
| 23_Q | 27_A | 1.072 | 0.90 | |
| 8_I | 47_P | 1.062 | 0.90 | |
| 110_E | 113_A | 1.053 | 0.89 | |
| 40_W | 45_S | 1.039 | 0.88 | |
| 64_T | 67_L | 1.023 | 0.87 | |
| 101_E | 104_Q | 1.007 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3op9A | 1 | 0.8222 | 99.8 | 0.426 | Contact Map | 0.716 |
| 3ivpA | 4 | 0.8667 | 99.7 | 0.433 | Contact Map | 0.689 |
| 3qwgA | 2 | 0.8148 | 99.7 | 0.439 | Contact Map | 0.722 |
| 3r1fA | 18 | 0.8963 | 99.7 | 0.44 | Contact Map | 0.741 |
| 1b0nA | 1 | 0.8 | 99.7 | 0.453 | Contact Map | 0.728 |
| 3lfpA | 1 | 0.6963 | 99.7 | 0.46 | Contact Map | 0.678 |
| 2ebyA | 2 | 0.7926 | 99.6 | 0.495 | Contact Map | 0.741 |
| 3u3wA | 2 | 0.9704 | 99.6 | 0.496 | Contact Map | 0.74 |
| 3bs3A | 1 | 0.5407 | 99.6 | 0.5 | Contact Map | 0.673 |
| 1adrA | 1 | 0.563 | 99.6 | 0.5 | Contact Map | 0.775 |
Sequence Conservation (Image Generated using WebLogo v3)