| UniProt: | P04951 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10519 | ||
| Length: | 248 (245) | ||
| Sequences: | 2013 | ||
| Seq/Len: | 8.22 |
| KDSB
Paralog alert: 0.32 [within 20: 0.03] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 27_K | 35_E | 4.99 | 1.00 | |
| 44_R | 64_E | 4.92 | 1.00 | |
| 58_V | 63_G | 3.443 | 1.00 | |
| 52_E | 56_R | 3.233 | 1.00 | |
| 18_G | 53_D | 3.147 | 1.00 | |
| 31_V | 35_E | 2.753 | 1.00 | |
| 31_V | 61_A | 2.702 | 1.00 | |
| 55_A | 59_E | 2.667 | 1.00 | |
| 49_T | 55_A | 2.589 | 1.00 | |
| 237_P | 241_E | 2.53 | 1.00 | |
| 23_D | 244_R | 2.509 | 1.00 | |
| 11_Y | 18_G | 2.473 | 1.00 | |
| 37_A | 97_V | 2.448 | 1.00 | |
| 38_R | 45_I | 2.339 | 1.00 | |
| 103_M | 243_V | 2.333 | 1.00 | |
| 34_L | 63_G | 2.318 | 1.00 | |
| 22_V | 240_L | 2.151 | 1.00 | |
| 240_L | 244_R | 2.135 | 1.00 | |
| 28_P | 57_A | 2.093 | 1.00 | |
| 108_I | 230_P | 2.04 | 1.00 | |
| 22_V | 237_P | 2.031 | 1.00 | |
| 201_S | 216_W | 1.949 | 1.00 | |
| 179_L | 225_V | 1.937 | 1.00 | |
| 234_V | 243_V | 1.881 | 1.00 | |
| 147_D | 151_Y | 1.867 | 1.00 | |
| 123_M | 214_V | 1.855 | 1.00 | |
| 36_R | 39_E | 1.831 | 1.00 | |
| 55_A | 67_M | 1.83 | 1.00 | |
| 16_L | 22_V | 1.826 | 1.00 | |
| 18_G | 51_H | 1.824 | 1.00 | |
| 41_G | 110_R | 1.814 | 1.00 | |
| 84_E | 193_R | 1.789 | 1.00 | |
| 47_V | 58_V | 1.772 | 1.00 | |
| 241_E | 244_R | 1.755 | 1.00 | |
| 151_Y | 220_K | 1.742 | 1.00 | |
| 5_V | 97_V | 1.739 | 1.00 | |
| 55_A | 65_V | 1.734 | 1.00 | |
| 69_R | 72_H | 1.73 | 1.00 | |
| 32_H | 36_R | 1.619 | 1.00 | |
| 24_I | 29_M | 1.607 | 1.00 | |
| 16_L | 237_P | 1.59 | 1.00 | |
| 15_R | 165_D | 1.586 | 1.00 | |
| 28_P | 31_V | 1.585 | 1.00 | |
| 122_G | 220_K | 1.579 | 1.00 | |
| 95_V | 186_G | 1.574 | 1.00 | |
| 81_E | 85_K | 1.545 | 1.00 | |
| 28_P | 32_H | 1.521 | 1.00 | |
| 129_P | 225_V | 1.518 | 1.00 | |
| 23_D | 26_G | 1.506 | 1.00 | |
| 56_R | 60_A | 1.503 | 1.00 | |
| 74_S | 77_E | 1.49 | 1.00 | |
| 108_I | 111_Q | 1.489 | 1.00 | |
| 129_P | 177_N | 1.482 | 0.99 | |
| 40_S | 110_R | 1.48 | 0.99 | |
| 52_E | 67_M | 1.457 | 0.99 | |
| 11_Y | 54_V | 1.45 | 0.99 | |
| 6_I | 82_V | 1.445 | 0.99 | |
| 42_A | 110_R | 1.445 | 0.99 | |
| 112_V | 184_I | 1.431 | 0.99 | |
| 56_R | 59_E | 1.416 | 0.99 | |
| 127_A | 223_V | 1.415 | 0.99 | |
| 189_A | 193_R | 1.41 | 0.99 | |
| 112_V | 186_G | 1.407 | 0.99 | |
| 114_D | 118_Q | 1.395 | 0.99 | |
| 200_P | 205_H | 1.393 | 0.99 | |
| 11_Y | 53_D | 1.388 | 0.99 | |
| 151_Y | 222_H | 1.386 | 0.99 | |
| 47_V | 63_G | 1.383 | 0.99 | |
| 49_T | 54_V | 1.368 | 0.99 | |
| 97_V | 104_I | 1.36 | 0.99 | |
| 72_H | 81_E | 1.356 | 0.99 | |
| 190_G | 194_R | 1.332 | 0.99 | |
| 125_T | 223_V | 1.294 | 0.98 | |
| 34_L | 61_A | 1.285 | 0.98 | |
| 46_I | 64_E | 1.278 | 0.98 | |
| 156_S | 160_I | 1.276 | 0.98 | |
| 241_E | 245_A | 1.268 | 0.98 | |
| 47_V | 54_V | 1.259 | 0.98 | |
| 227_Q | 230_P | 1.252 | 0.98 | |
| 75_G | 96_N | 1.238 | 0.98 | |
| 46_I | 66_C | 1.224 | 0.97 | |
| 69_R | 81_E | 1.223 | 0.97 | |
| 127_A | 179_L | 1.212 | 0.97 | |
| 182_L | 226_A | 1.204 | 0.97 | |
| 36_R | 106_A | 1.201 | 0.97 | |
| 24_I | 247_M | 1.184 | 0.97 | |
| 165_D | 208_M | 1.178 | 0.96 | |
| 36_R | 104_I | 1.142 | 0.96 | |
| 93_V | 116_L | 1.141 | 0.96 | |
| 116_L | 188_R | 1.136 | 0.95 | |
| 11_Y | 51_H | 1.132 | 0.95 | |
| 103_M | 247_M | 1.131 | 0.95 | |
| 16_L | 240_L | 1.124 | 0.95 | |
| 59_E | 64_E | 1.115 | 0.95 | |
| 27_K | 31_V | 1.111 | 0.95 | |
| 153_L | 215_L | 1.11 | 0.95 | |
| 73_Q | 77_E | 1.107 | 0.94 | |
| 66_C | 82_V | 1.092 | 0.94 | |
| 23_D | 28_P | 1.09 | 0.94 | |
| 121_V | 222_H | 1.088 | 0.94 | |
| 29_M | 234_V | 1.084 | 0.94 | |
| 70_A | 73_Q | 1.074 | 0.93 | |
| 4_V | 46_I | 1.071 | 0.93 | |
| 104_I | 109_I | 1.071 | 0.93 | |
| 49_T | 65_V | 1.067 | 0.93 | |
| 132_N | 135_E | 1.063 | 0.93 | |
| 46_I | 82_V | 1.062 | 0.93 | |
| 194_R | 219_E | 1.047 | 0.92 | |
| 57_A | 60_A | 1.043 | 0.92 | |
| 87_A | 189_A | 1.033 | 0.91 | |
| 115_N | 222_H | 1.032 | 0.91 | |
| 133_A | 136_A | 1.032 | 0.91 | |
| 25_N | 103_M | 1.031 | 0.91 | |
| 205_H | 208_M | 1.029 | 0.91 | |
| 153_L | 203_L | 1.025 | 0.91 | |
| 27_K | 32_H | 1.02 | 0.91 | |
| 75_G | 98_Q | 1.02 | 0.91 | |
| 101_E | 233_G | 1.009 | 0.90 | |
| 52_E | 59_E | 1.002 | 0.90 | |
| 44_R | 86_C | 1 | 0.89 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3k8dA | 4 | 0.996 | 100 | 0.482 | Contact Map | 0.792 |
| 1vicA | 2 | 1 | 100 | 0.49 | Contact Map | 0.792 |
| 3oamA | 4 | 0.996 | 100 | 0.493 | Contact Map | 0.768 |
| 1h7eA | 2 | 0.9476 | 100 | 0.495 | Contact Map | 0.769 |
| 4fcuA | 1 | 0.9919 | 100 | 0.498 | Contact Map | 0.689 |
| 3tqdA | 1 | 0.9919 | 100 | 0.506 | Contact Map | 0.735 |
| 2y6pA | 3 | 0.9355 | 100 | 0.515 | Contact Map | 0.837 |
| 1eziA | 2 | 0.8669 | 100 | 0.526 | Contact Map | 0.804 |
| 1qwjA | 4 | 0.8468 | 100 | 0.536 | Contact Map | 0.772 |
| 3st8A | 1 | 0.9315 | 99.9 | 0.594 | Contact Map | 0.562 |
Sequence Conservation (Image Generated using WebLogo v3)