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OPENSEQ.org
FtsL - FtsW
Genes: A B A+B
Length: 117 403 457
Sequences: 434 3310 110
Seq/Len: 3.71 8.21 0.24
MirrorTree (Pazo et al. 2001) 0.61
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show HHblits results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.01 0.01 0.00
2 0.01 0.01 0.00
5 0.01 0.01 0.05
10 0.01 0.01 0.20
20 0.01 0.01 0.21
100 0.01 0.04 0.40
∞ 0.04 0.12 0.54
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
77_N 326_I 1.65 0.46 0.00
43_A 162_M 1.51 0.37 0.00
34_E 105_S 1.48 0.35 0.00
70_E 134_K 1.45 0.33 0.00
101_K 293_I 1.42 0.32 0.00
105_L 350_F 1.38 0.29 0.00
90_L 273_T 1.36 0.28 0.00
93_P 103_A 1.34 0.27 0.00
47_S 364_S 1.32 0.27 0.00
2_S 273_T 1.25 0.23 0.00
104_G 165_D 1.25 0.23 0.00
47_S 22_G 1.22 0.22 0.00
81_G 56_I 1.21 0.21 0.00
55_K 239_L 1.16 0.19 0.00
82_D 265_Y 1.16 0.19 0.00
93_P 101_G 1.16 0.19 0.00
6_Y 182_C 1.14 0.18 0.00
41_F 254_F 1.13 0.18 0.00
12_Q 138_Y 1.13 0.18 0.00
53_V 171_I 1.13 0.18 0.00
60_Y 31_S 1.12 0.18 0.00
31_T 239_L 1.12 0.18 0.00
18_P 281_A 1.12 0.18 0.00
105_L 154_L 1.12 0.18 0.00
81_G 229_D 1.12 0.18 0.00
28_A 306_I 1.10 0.17 0.00
44_A 294_F 1.10 0.17 0.00
76_E 308_R 1.10 0.17 0.00
79_Q 26_V 1.09 0.17 0.00
104_G 163_Q 1.08 0.16 0.00
72_Q 64_L 1.07 0.16 0.00
80_I 351_I 1.07 0.16 0.00
66_V 25_L 1.06 0.16 0.00
78_K 170_M 1.06 0.15 0.00
96_I 353_Y 1.05 0.15 0.00
18_P 350_F 1.05 0.15 0.00
45_V 68_F 1.04 0.15 0.00
12_Q 46_F 1.04 0.15 0.00
23_I 91_I 1.03 0.15 0.00
34_E 119_F 1.03 0.15 0.00
105_L 170_M 1.03 0.14 0.00
34_E 340_L 1.02 0.14 0.00
44_A 158_G 1.02 0.14 0.00
22_V 327_A 1.01 0.14 0.00
112_V 300_V 1.01 0.14 0.00
75_S 183_S 1.01 0.14 0.00
6_Y 260_E 1.01 0.14 0.00
44_A 298_F 1.00 0.14 0.00
80_I 310_C 1.00 0.14 0.00
96_I 188_K 1.00 0.14 0.00
50_L 229_D 1.00 0.14 0.00
49_S 265_Y 0.99 0.14 0.00
57_Y 229_D 0.99 0.13 0.00
60_Y 322_I 0.97 0.13 0.00
15_A 227_L 0.97 0.13 0.00
104_G 97_G 0.96 0.13 0.00
93_P 170_M 0.96 0.12 0.00
40_L 201_F 0.96 0.12 0.00
66_V 229_D 0.95 0.12 0.00
63_N 105_S 0.95 0.12 0.00
70_E 56_I 0.94 0.12 0.00
105_L 105_S 0.94 0.12 0.00
104_G 253_I 0.94 0.12 0.00
8_P 351_I 0.93 0.12 0.00
27_R 25_L 0.93 0.12 0.00
69_L 246_Y 0.93 0.12 0.00
24_V 158_G 0.93 0.12 0.00
60_Y 272_H 0.92 0.12 0.00
68_K 198_G 0.92 0.12 0.00
19_E 92_S 0.92 0.12 0.00
2_S 125_I 0.91 0.11 0.00
82_D 107_F 0.91 0.11 0.00
105_L 34_I 0.90 0.11 0.00
34_E 248_I 0.90 0.11 0.00
56_A 103_A 0.90 0.11 0.00
84_E 221_L 0.90 0.11 0.00
47_S 292_V 0.90 0.11 0.00
23_I 25_L 0.90 0.11 0.00
78_K 226_S 0.89 0.11 0.00
63_N 119_F 0.89 0.11 0.00
4_L 330_S 0.89 0.11 0.00
19_E 183_S 0.88 0.11 0.00
108_K 103_A 0.88 0.10 0.00
20_K 59_G 0.88 0.10 0.00
37_L 165_D 0.88 0.10 0.00
28_A 280_I 0.87 0.10 0.00
4_L 361_L 0.87 0.10 0.00
76_E 351_I 0.87 0.10 0.00
7_Q 228_E 0.87 0.10 0.00
104_G 160_I 0.87 0.10 0.00
93_P 314_F 0.86 0.10 0.00
78_K 334_L 0.86 0.10 0.00
53_V 124_V 0.86 0.10 0.00
76_E 190_L 0.86 0.10 0.00
34_E 167_G 0.86 0.10 0.00
109_D 103_A 0.86 0.10 0.00
104_G 167_G 0.86 0.10 0.00
43_A 129_A 0.85 0.10 0.00
63_N 160_I 0.85 0.10 0.00
111_K 31_S 0.85 0.10 0.00
76_E 362_L 0.85 0.10 0.00
86_S 323_S 0.85 0.10 0.00
96_I 55_L 0.85 0.10 0.00
65_E 57_A 0.84 0.10 0.00
9_E 229_D 0.84 0.10 0.00
69_L 273_T 0.84 0.10 0.00
34_E 54_A 0.84 0.10 0.00
14_H 291_F 0.84 0.10 0.00
41_F 103_A 0.84 0.10 0.00
85_K 47_F 0.84 0.10 0.00
63_N 168_T 0.84 0.10 0.00
1_M 239_L 0.84 0.10 0.00
70_E 228_E 0.84 0.10 0.00
12_Q 199_I 0.84 0.10 0.00
65_E 65_M 0.83 0.10 0.00
97_M 103_A 0.83 0.10 0.00
67_Q 20_L 0.83 0.09 0.00
75_S 306_I 0.83 0.09 0.00
22_V 22_G 0.83 0.09 0.00
75_S 47_F 0.83 0.09 0.00
46_L 256_L 0.83 0.09 0.00
19_E 326_I 0.83 0.09 0.00
35_K 50_R 0.83 0.09 0.00
59_A 84_L 0.83 0.09 0.00
22_V 188_K 0.83 0.09 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
8096 0.24 FtsL - FtsW Δgene:(1, 20) A:(1E-06, 8) B:(1E-06, 8) msa: HHblits (2015_06) 0.00 Done - Shared
8093 0.17 FtsL - FtsW Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) 0.01 Done - Shared
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