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OPENSEQ.org

subDE

Genes: A B A+B
Length: 248 241 467
Sequences: 3308 4041 2720
Seq/Len: 13.34 16.77 5.82
MirrorTree (Pazo et al. 2001) 0.99
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show HHblits results] - Maybe useful in deciding what regions to trim.

Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.10 0.09 5.52
2 0.10 0.10 5.54
5 0.11 0.11 5.55
10 0.11 0.11 5.55
20 0.12 0.12 5.55
100 0.15 0.16 5.55
0.27 0.25 5.56
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!

GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution.
Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
67_D 72_A 4.32 1.00 1.00
189_K 196_K 4.19 1.00 1.00
221_N 230_T 4.16 1.00 1.00
101_P 106_T 4.13 1.00 1.00
136_F 146_V 4.08 1.00 1.00
223_E 232_E 4.01 1.00 1.00
38_R 43_S 3.96 1.00 1.00
208_L 217_L 3.86 1.00 1.00
64_A 69_E 3.85 1.00 1.00
193_K 200_I 3.83 1.00 1.00
179_E 188_S 3.83 1.00 1.00
39_D 44_E 3.82 1.00 1.00
35_V 40_I 3.81 1.00 1.00
210_V 219_T 3.74 1.00 1.00
71_M 76_C 3.74 1.00 1.00
222_P 231_K 3.73 1.00 1.00
69_V 74_I 3.72 1.00 1.00
97_T 102_T 3.69 1.00 1.00
62_I 67_I 3.69 1.00 1.00
218_K 227_H 3.67 1.00 1.00
133_I 143_F 3.67 1.00 1.00
175_N 184_V 3.67 1.00 1.00
105_E 110_E 3.66 1.00 1.00
188_I 195_I 3.66 1.00 1.00
178_D 187_K 3.65 1.00 1.00
159_N 168_R 3.62 1.00 1.00
65_L 70_I 3.61 1.00 1.00
89_V 94_V 3.60 1.00 1.00
33_V 38_I 3.60 1.00 1.00
225_I 234_L 3.59 1.00 1.00
154_H 163_V 3.56 1.00 1.00
111_I 116_V 3.56 1.00 1.00
192_I 199_L 3.56 1.00 1.00
99_E 104_N 3.56 1.00 1.00
104_V 109_V 3.55 1.00 1.00
157_K 166_D 3.54 1.00 1.00
177_T 186_H 3.53 1.00 1.00
186_L 193_E 3.51 1.00 1.00
95_R 100_W 3.51 1.00 1.00
63_C 68_V 3.48 1.00 1.00
224_E 233_E 3.47 1.00 1.00
102_V 107_M 3.45 1.00 1.00
43_L 48_L 3.45 1.00 1.00
85_N 90_D 3.45 1.00 1.00
204_K 213_T 3.43 1.00 1.00
227_K 236_E 3.42 1.00 1.00
181_I 190_T 3.42 1.00 1.00
103_T 108_T 3.42 1.00 1.00
36_R 41_Q 3.42 1.00 1.00
174_K 183_E 3.38 1.00 1.00
82_I 87_T 3.38 1.00 1.00
57_R 62_S 3.38 1.00 1.00
196_L 203_K 3.37 1.00 1.00
68_N 73_H 3.36 1.00 1.00
226_E 235_E 3.34 1.00 1.00
214_D 223_G 3.34 1.00 1.00
84_I 89_I 3.33 1.00 1.00
169_R 178_Q 3.31 1.00 1.00
86_R 91_K 3.31 1.00 1.00
93_S 98_N 3.31 1.00 1.00
153_Y 162_F 3.30 1.00 1.00
167_S 176_G 3.29 1.00 1.00
109_R 114_Q 3.29 1.00 1.00
212_R 221_Q 3.28 1.00 1.00
219_I 228_M 3.26 1.00 1.00
59_V 64_I 3.26 1.00 1.00
134_V 144_G 3.26 1.00 1.00
209_A 218_A 3.25 1.00 1.00
176_Y 185_Y 3.25 1.00 1.00
145_Y 154_F 3.25 1.00 1.00
206_I 215_I 3.24 1.00 1.00
203_G 212_A 3.23 1.00 1.00
131_A 141_L 3.23 1.00 1.00
42_V 47_C 3.23 1.00 1.00
171_F 180_S 3.22 1.00 1.00
211_M 220_V 3.21 1.00 1.00
114_L 119_L 3.20 1.00 1.00
106_Y 111_S 3.19 1.00 1.00
180_A 189_M 3.19 1.00 1.00
49_S 54_I 3.17 1.00 1.00
60_R 65_E 3.17 1.00 1.00
166_K 175_E 3.15 1.00 1.00
160_A 169_A 3.15 1.00 1.00
155_A 164_Q 3.12 1.00 1.00
100_D 105_E 3.12 1.00 1.00
161_I 170_I 3.11 1.00 1.00
220_L 229_F 3.11 1.00 1.00
147_T 156_M 3.10 1.00 1.00
117_R 122_Q 3.09 1.00 1.00
41_V 46_V 3.09 1.00 1.00
191_V 198_S 3.09 1.00 1.00
165_A 174_S 3.07 1.00 1.00
110_Y 115_A 3.07 1.00 1.00
143_R 152_Q 3.05 1.00 1.00
113_S 118_N 3.04 1.00 1.00
190_L 197_S 3.02 1.00 1.00
138_F 148_E 3.02 1.00 1.00
44_G 49_A 3.01 1.00 1.00
96_L 101_F 3.01 1.00 1.00
45_V 50_V 3.00 1.00 1.00
112_A 117_S 3.00 1.00 1.00
228_Y 237_V 2.99 1.00 1.00
70_C 75_G 2.98 1.00 1.00
194_A 201_I 2.97 1.00 1.00
132_L 142_L 2.97 1.00 1.00
58_T 63_S 2.96 1.00 1.00
56_E 61_P 2.94 1.00 1.00
83_V 88_L 2.94 1.00 1.00
197_E 204_Q 2.92 1.00 1.00
108_T 113_T 2.90 1.00 1.00
50_V 55_T 2.90 1.00 1.00
54_Q 59_M 2.89 1.00 1.00
73_F 78_M 2.88 1.00 1.00
142_P 151_P 2.86 1.00 1.00
72_A 77_A 2.85 1.00 1.00
230_A 239_K 2.83 1.00 1.00
185_D 192_K 2.83 1.00 1.00
37_G 42_T 2.79 1.00 1.00
129_I 139_V 2.78 1.00 1.00
94_H 99_H 2.78 1.00 1.00
213_R 222_P 2.76 1.00 1.00
170_E 179_S 2.75 1.00 1.00
55_D 60_E 2.75 1.00 1.00
32_A 37_A 2.74 1.00 1.00
152_T 161_T 2.74 1.00 1.00
127_F 137_F 2.72 1.00 1.00
98_V 103_Y 2.71 1.00 1.00
146_Q 155_H 2.70 1.00 1.00
107_I 112_V 2.68 1.00 1.00
90_E 95_E 2.68 1.00 1.00
26_V 31_I 2.67 1.00 1.00
115_K 120_A 2.62 1.00 1.00
74_A 79_S 2.61 1.00 1.00
198_V 205_V 2.61 1.00 1.00
130_S 140_A 2.60 1.00 1.00
202_G 211_N 2.58 1.00 1.00
87_A 92_A 2.58 1.00 1.00
47_K 52_K 2.58 1.00 1.00
168_V 177_A 2.58 1.00 1.00
88_R 93_R 2.57 1.00 1.00
80_A 85_A 2.56 1.00 1.00
217_L 226_F 2.52 1.00 1.00
78_A 83_A 2.50 1.00 1.00
205_N 214_N 2.48 1.00 1.00
216_S 225_N 2.46 1.00 1.00
137_D 147_D 2.46 1.00 1.00
231_E 240_D 2.45 1.00 1.00
66_D 71_D 2.45 1.00 1.00
172_L 181_L 2.45 1.00 1.00
27_K 32_K 2.43 1.00 1.00
144_L 153_L 2.43 1.00 1.00
51_A 56_S 2.43 1.00 1.00
195_L 202_L 2.41 1.00 1.00
163_R 172_S 2.39 1.00 1.00
77_T 82_I 2.38 1.00 1.00
187_T 194_A 2.36 1.00 1.00
34_G 39_G 2.34 1.00 1.00
156_W 165_C 2.33 1.00 1.00
92_Q 97_Q 2.33 1.00 1.00
229_V 238_I 2.32 1.00 1.00
30_S 35_S 2.32 1.00 1.00
124_R 134_S 2.31 1.00 1.00
91_C 96_T 2.31 1.00 1.00
158_A 167_A 2.29 1.00 1.00
28_K 33_L 2.27 1.00 0.99
76_L 81_L 2.27 1.00 0.99
52_K 57_P 2.26 1.00 0.99
53_L 58_L 2.19 1.00 0.99
139_D 149_K 2.17 1.00 0.99
118_Y 123_F 2.15 1.00 0.99
164_G 173_A 2.15 1.00 0.99
48_K 53_R 2.12 1.00 0.99
201_S 210_L 2.12 1.00 0.99
150_S 159_S 2.10 1.00 0.99
207_E 216_E 2.06 1.00 0.99
183_T 192_K 2.06 1.00 0.99
184_D 191_L 2.05 1.00 0.99
148_D 157_D 2.03 1.00 0.99
31_T 36_T 2.03 1.00 0.99
232_I 241_I 2.02 1.00 0.99
215_Q 224_Q 2.00 1.00 0.99
182_E 191_L 1.96 1.00 0.99
23_Q 28_I 1.94 1.00 0.98
81_R 86_K 1.94 1.00 0.98
9_V 14_T 1.91 1.00 0.98
173_E 182_Q 1.88 1.00 0.98
141_T 150_G 1.84 1.00 0.98
40_I 45_G 1.84 1.00 0.98
29_G 34_G 1.80 1.00 0.98
149_P 158_P 1.79 1.00 0.98
17_F 22_F 1.72 1.00 0.97
199_V 206_M 1.72 1.00 0.97
7_I 12_V 1.68 1.00 0.96
25_A 30_A 1.66 1.00 0.96
121_S 126_E 1.66 1.00 0.96
46_E 51_E 1.63 0.99 0.96
16_L 21_L 1.63 0.99 0.96
2_S 7_E 1.60 0.99 0.95
24_E 29_E 1.58 0.99 0.95
19_V 24_V 1.53 0.99 0.94
13_D 18_E 1.50 0.99 0.93
135_G 145_G 1.49 0.99 0.93
1_M 6_S 1.48 0.99 0.93
8_T 13_N 1.46 0.99 0.92
128_G 138_G 1.43 0.98 0.91
116_Q 121_L 1.40 0.98 0.90
20_E 25_E 1.38 0.98 0.89
5_R 10_R 1.36 0.98 0.88
123_G 133_M 1.33 0.97 0.87
200_Q 207_E 1.33 0.97 0.87
15_H 20_R 1.29 0.96 0.85
6_A 11_G 1.27 0.96 0.83
184_D 193_E 1.19 0.94 0.78
120_Q 125_E 1.17 0.93 0.76
140_G 149_K 1.17 0.93 0.76
10_F 15_F 1.17 0.93 0.76
126_P 136_P 1.06 0.88 0.67
61_K 66_K 1.05 0.86 0.65
3_Y 8_Y 1.02 0.85 0.62
21_Y 26_Y 1.02 0.84 0.62
122_N 132_A 1.01 0.83 0.60
140_G 150_G 1.00 0.82 0.59
125_R 135_R 0.98 0.81 0.57
12_P 17_P 0.93 0.76 0.51
4_D 9_D 0.87 0.69 0.43
119_T 124_G 0.87 0.69 0.43
11_S 16_S 0.85 0.67 0.41
122_N 127_D 0.84 0.66 0.40
22_A 27_A 0.81 0.61 0.35
151_G 160_G 0.81 0.60 0.35
200_Q 209_K 0.75 0.52 0.28
79_D 84_D 0.74 0.50 0.27
186_L 195_I 0.70 0.44 0.23
183_T 190_T 0.58 0.29 0.13
185_D 194_A 0.57 0.27 0.12
121_S 131_G 0.56 0.26 0.11
18_Q 23_Q 0.50 0.20 0.08
202_G 209_K 0.45 0.15 0.05
14_G 19_G 0.43 0.14 0.05
139_D 148_E 0.42 0.14 0.05
44_G 198_S 0.42 0.13 0.04
119_T 122_Q 0.39 0.11 0.04
191_V 49_A 0.38 0.11 0.03
182_E 189_M 0.37 0.10 0.03
201_S 208_E 0.37 0.10 0.03
162_G 171_G 0.37 0.10 0.03
124_R 124_G 0.36 0.10 0.03
124_R 133_M 0.33 0.08 0.02
37_G 194_A 0.33 0.08 0.02
214_D 222_P 0.33 0.08 0.02
181_I 193_E 0.33 0.08 0.02
213_R 223_G 0.31 0.07 0.02
1_M 5_R 0.31 0.07 0.02
202_G 210_L 0.30 0.07 0.02
38_R 44_E 0.30 0.07 0.02
39_D 43_S 0.29 0.07 0.02
224_E 227_H 0.29 0.07 0.02
2_S 5_R 0.28 0.06 0.01
199_V 210_L 0.28 0.06 0.01
2_S 6_S 0.27 0.06 0.01
214_D 224_Q 0.27 0.06 0.01
43_L 39_G 0.26 0.06 0.01
34_G 48_L 0.26 0.06 0.01
200_Q 210_L 0.26 0.06 0.01
66_D 73_H 0.26 0.06 0.01
199_V 208_E 0.26 0.06 0.01
226_E 239_K 0.25 0.05 0.01
68_N 71_D 0.25 0.05 0.01
70_C 226_F 0.25 0.05 0.01
1_M 7_E 0.25 0.05 0.01
201_S 211_N 0.24 0.05 0.01
104_V 145_G 0.24 0.05 0.01
230_A 235_E 0.24 0.05 0.01
135_G 109_V 0.24 0.05 0.01
88_R 89_I 0.23 0.05 0.01
218_K 233_E 0.23 0.05 0.01
66_D 100_W 0.23 0.05 0.01
186_L 190_T 0.23 0.05 0.01
217_L 75_G 0.22 0.04 0.01
95_R 71_D 0.22 0.04 0.01
155_A 152_Q 0.22 0.04 0.01
6_A 14_T 0.22 0.04 0.01
32_A 77_A 0.22 0.04 0.01
9_V 11_G 0.22 0.04 0.01
134_V 48_L 0.22 0.04 0.01
143_R 164_Q 0.22 0.04 0.01
72_A 37_A 0.22 0.04 0.01
43_L 144_G 0.21 0.04 0.01
6_A 10_R 0.21 0.04 0.01
51_A 63_S 0.21 0.04 0.01
5_R 11_G 0.21 0.04 0.01
214_D 221_Q 0.21 0.04 0.01
35_V 198_S 0.21 0.04 0.01
175_N 197_S 0.20 0.04 0.01
34_G 153_L 0.20 0.04 0.01
134_V 46_V 0.20 0.04 0.01
15_H 25_E 0.20 0.04 0.01
175_N 200_I 0.20 0.04 0.01
20_E 20_R 0.20 0.04 0.01
104_V 74_I 0.20 0.04 0.01
190_L 184_V 0.19 0.04 0.01
37_G 44_E 0.19 0.04 0.01
187_T 42_T 0.19 0.04 0.01
144_L 39_G 0.19 0.04 0.01
30_S 34_G 0.19 0.04 0.01
75_G 80_G 0.19 0.04 0.01
3_Y 9_D 0.19 0.04 0.01
41_V 144_G 0.19 0.04 0.01
39_D 42_T 0.19 0.04 0.01
16_L 13_N 0.18 0.04 0.01
193_K 184_V 0.18 0.04 0.01
12_P 16_S 0.18 0.04 0.01
40_I 42_T 0.18 0.04 0.01
21_Y 27_A 0.18 0.04 0.01
69_V 109_V 0.18 0.04 0.01
73_F 85_A 0.18 0.04 0.01
14_G 23_Q 0.18 0.04 0.01
8_T 21_L 0.18 0.04 0.01
80_A 78_M 0.18 0.04 0.01
4_D 8_Y 0.18 0.04 0.01
29_G 35_S 0.18 0.04 0.01
179_E 186_H 0.18 0.04 0.01
11_S 17_P 0.18 0.04 0.01
7_I 11_G 0.18 0.04 0.01
6_A 12_V 0.18 0.04 0.01
90_E 91_K 0.17 0.03 0.01
21_Y 25_E 0.17 0.03 0.01
22_A 26_Y 0.17 0.03 0.01
37_G 45_G 0.17 0.03 0.01
116_Q 124_G 0.17 0.03 0.01
20_E 26_Y 0.17 0.03 0.01
224_E 230_T 0.17 0.03 0.01
25_A 29_E 0.17 0.03 0.01
233_E 240_D 0.17 0.03 0.01
125_R 138_G 0.17 0.03 0.01
197_E 207_E 0.17 0.03 0.01
18_Q 19_G 0.17 0.03 0.01
143_R 150_G 0.17 0.03 0.01
107_I 74_I 0.16 0.03 0.00
132_L 168_R 0.16 0.03 0.00
191_V 40_I 0.16 0.03 0.00
159_N 142_L 0.16 0.03 0.00
221_N 233_E 0.16 0.03 0.00
223_E 230_T 0.16 0.03 0.00
177_T 188_S 0.16 0.03 0.00
40_I 44_E 0.16 0.03 0.00
115_K 156_M 0.16 0.03 0.00
233_E 241_I 0.16 0.03 0.00
216_S 223_G 0.16 0.03 0.00
231_E 196_K 0.16 0.03 0.00
128_G 135_R 0.16 0.03 0.00
21_Y 23_Q 0.16 0.03 0.00
189_K 240_D 0.16 0.03 0.00
12_P 8_Y 0.15 0.03 0.00
69_V 112_V 0.15 0.03 0.00
198_V 208_E 0.15 0.03 0.00
178_D 166_D 0.15 0.03 0.00
39_D 45_G 0.15 0.03 0.00
7_I 13_N 0.15 0.03 0.00
233_E 239_K 0.15 0.03 0.00
157_K 187_K 0.15 0.03 0.00
221_N 232_E 0.15 0.03 0.00
8_T 12_V 0.15 0.03 0.00
5_R 6_S 0.15 0.03 0.00
227_K 237_V 0.15 0.03 0.00
31_T 177_A 0.15 0.03 0.00
3_Y 17_P 0.15 0.03 0.00
37_G 221_Q 0.15 0.03 0.00
184_D 190_T 0.15 0.03 0.00
37_G 191_L 0.15 0.03 0.00
40_I 194_A 0.15 0.03 0.00
192_I 215_I 0.15 0.03 0.00
168_V 36_T 0.14 0.03 0.00
231_E 236_E 0.14 0.03 0.00
228_Y 236_E 0.14 0.03 0.00
6_A 6_S 0.14 0.03 0.00
4_D 22_F 0.14 0.03 0.00
38_R 188_S 0.14 0.03 0.00
5_R 12_V 0.14 0.03 0.00
7_I 10_R 0.14 0.03 0.00
20_E 24_V 0.14 0.03 0.00
3_Y 13_N 0.14 0.03 0.00
232_I 240_D 0.14 0.03 0.00
123_G 132_A 0.14 0.03 0.00
18_Q 26_Y 0.14 0.03 0.00
8_T 8_Y 0.14 0.03 0.00
4_D 10_R 0.14 0.03 0.00
208_L 195_I 0.14 0.03 0.00
64_A 72_A 0.14 0.03 0.00
5_R 9_D 0.14 0.03 0.00
67_D 69_E 0.14 0.03 0.00
1_M 240_D 0.14 0.03 0.00
3_Y 16_S 0.14 0.03 0.00
27_K 29_E 0.14 0.03 0.00
188_I 217_L 0.14 0.03 0.00
220_L 234_L 0.13 0.03 0.00
19_V 25_E 0.13 0.03 0.00
212_R 42_T 0.13 0.03 0.00
1_M 11_G 0.13 0.03 0.00
101_P 100_W 0.13 0.03 0.00
50_V 62_S 0.13 0.03 0.00
74_A 66_K 0.13 0.03 0.00
20_E 27_A 0.13 0.03 0.00
193_K 203_K 0.13 0.03 0.00
61_K 79_S 0.13 0.03 0.00
180_A 186_H 0.13 0.03 0.00
199_V 209_K 0.13 0.03 0.00
161_I 142_L 0.13 0.03 0.00
192_I 202_L 0.13 0.03 0.00
21_Y 24_V 0.13 0.03 0.00
179_E 43_S 0.13 0.03 0.00
6_A 7_E 0.13 0.03 0.00
7_I 14_T 0.13 0.03 0.00
225_I 229_F 0.13 0.03 0.00
149_P 138_G 0.13 0.03 0.00
141_T 149_K 0.13 0.03 0.00
147_T 120_A 0.13 0.03 0.00
41_V 45_G 0.13 0.03 0.00
9_V 12_V 0.13 0.03 0.00
232_I 237_V 0.13 0.03 0.00
4_D 16_S 0.13 0.03 0.00
19_V 23_Q 0.13 0.03 0.00
42_V 195_I 0.13 0.03 0.00
155_A 154_F 0.13 0.03 0.00
35_V 194_A 0.13 0.03 0.00
102_V 112_V 0.13 0.03 0.00
187_T 45_G 0.13 0.03 0.00
145_Y 164_Q 0.13 0.03 0.00
14_G 15_F 0.13 0.03 0.00
16_L 24_V 0.12 0.03 0.00
2_S 11_G 0.12 0.03 0.00
22_A 25_E 0.12 0.03 0.00
110_Y 95_E 0.12 0.03 0.00
182_E 42_T 0.12 0.03 0.00
11_S 9_D 0.12 0.03 0.00
213_R 221_Q 0.12 0.03 0.00
40_I 46_V 0.12 0.03 0.00
107_I 107_M 0.12 0.03 0.00
17_F 17_P 0.12 0.03 0.00
68_N 106_T 0.12 0.03 0.00
128_G 158_P 0.12 0.03 0.00
119_T 121_L 0.12 0.03 0.00
19_V 21_L 0.12 0.03 0.00
4_D 11_G 0.12 0.03 0.00
65_L 76_C 0.12 0.03 0.00
17_F 9_D 0.12 0.03 0.00
95_R 106_T 0.12 0.03 0.00
207_E 52_K 0.12 0.03 0.00
19_V 26_Y 0.12 0.03 0.00
13_D 17_P 0.12 0.03 0.00
14_G 16_S 0.12 0.03 0.00
10_F 19_G 0.12 0.03 0.00
231_E 239_K 0.12 0.03 0.00
227_K 240_D 0.12 0.03 0.00
132_L 170_I 0.12 0.03 0.00
11_S 22_F 0.12 0.03 0.00
120_Q 121_L 0.12 0.03 0.00
17_F 16_S 0.12 0.03 0.00
171_F 197_S 0.12 0.03 0.00
12_P 22_F 0.12 0.03 0.00
217_L 218_A 0.12 0.03 0.00
100_D 106_T 0.12 0.03 0.00
123_G 125_E 0.12 0.03 0.00
120_Q 133_M 0.12 0.03 0.00
228_Y 241_I 0.12 0.03 0.00
101_P 73_H 0.12 0.03 0.00
13_D 15_F 0.12 0.03 0.00
8_T 14_T 0.12 0.03 0.00
9_V 13_N 0.12 0.03 0.00
71_M 70_I 0.12 0.03 0.00
102_V 106_T 0.12 0.03 0.00
6_A 9_D 0.12 0.03 0.00
12_P 18_E 0.12 0.03 0.00
2_S 13_N 0.12 0.03 0.00
10_F 18_E 0.12 0.03 0.00
212_R 223_G 0.12 0.03 0.00
10_F 14_T 0.12 0.03 0.00
101_P 71_D 0.12 0.03 0.00
1_M 10_R 0.12 0.03 0.00
118_Y 137_F 0.12 0.03 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

WARNING: The input alignment may be corrupted!
  • Sequence A is very similar to Sequence B (HHΔ = 0.101), these maybe paralogs! HHΔ is a measure (0 to 1) of how different two alignments are (the larger the value the more different they are).

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