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cIm_K_4_isp_2_human
Genes: A B A+B
Length: 98 274 305
Sequences: 6983 609 163
Seq/Len: 71.26 2.22 0.53
MirrorTree (Pazo et al. 2001) 0.13
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.00 0.00 0.00
2 0.00 0.00 0.00
5 0.00 0.00 0.00
10 0.00 0.00 0.00
20 0.00 0.00 0.01
100 0.01 0.00 0.03
∞ 0.04 0.00 0.44
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
6_M 257_N 1.17 0.33 0.00
44_G 102_S 1.03 0.24 0.00
14_I 89_S 1.02 0.24 0.00
40_L 121_T 1.01 0.23 0.00
33_L 91_Y 1.00 0.22 0.00
76_A 128_A 0.98 0.21 0.00
21_V 165_M 0.95 0.20 0.00
13_T 117_V 0.95 0.20 0.00
39_S 213_L 0.93 0.19 0.00
13_T 129_A 0.92 0.18 0.00
42_I 264_E 0.90 0.18 0.00
44_G 211_V 0.90 0.17 0.00
16_L 255_P 0.90 0.17 0.00
69_C 124_G 0.90 0.17 0.00
17_L 123_V 0.89 0.17 0.00
13_T 114_S 0.89 0.17 0.00
13_T 120_V 0.88 0.17 0.00
63_M 184_I 0.87 0.16 0.00
74_G 121_T 0.87 0.16 0.00
69_C 216_V 0.87 0.16 0.00
6_M 248_R 0.87 0.16 0.00
43_M 136_F 0.86 0.16 0.00
80_S 127_Y 0.86 0.16 0.00
12_F 247_G 0.85 0.15 0.00
30_L 268_D 0.85 0.15 0.00
39_S 218_T 0.85 0.15 0.00
82_S 264_E 0.84 0.15 0.00
44_G 71_N 0.84 0.15 0.00
20_L 99_S 0.84 0.15 0.00
8_I 99_S 0.83 0.15 0.00
32_C 92_R 0.83 0.14 0.00
28_S 102_S 0.82 0.14 0.00
44_G 66_A 0.82 0.14 0.00
73_V 65_V 0.81 0.14 0.00
93_L 134_T 0.81 0.14 0.00
42_I 247_G 0.81 0.14 0.00
31_L 135_Q 0.80 0.13 0.00
33_L 123_V 0.80 0.13 0.00
31_L 213_L 0.80 0.13 0.00
5_Y 201_D 0.79 0.13 0.00
17_L 204_R 0.79 0.13 0.00
30_L 64_L 0.79 0.13 0.00
5_Y 69_G 0.79 0.13 0.00
70_E 81_T 0.78 0.13 0.00
71_A 259_E 0.78 0.13 0.00
59_V 95_E 0.78 0.13 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
5749 0 cIm_K_20_isp_2_human Δgene:(1, ∞) A:(1E-20, 8) B:(1E-02, 8) msa: Jackhmmer (2016_06b) Killed - Shared
5748 0.53 cIm_K_4_isp_2_human Δgene:(1, ∞) A:(1E-04, 8) B:(1E-02, 8) msa: Jackhmmer (2016_06b) 0.00 Done - Shared
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