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OPENSEQ.org
FtsB-FtsL
Genes: A B A+B
Length: 103 121 208
Sequences: 2861 1785 130
Seq/Len: 27.78 14.75 0.62
MirrorTree (Pazo et al. 2001) 0.93
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.00 0.00 0.00
2 0.00 0.00 0.00
5 0.00 0.00 0.00
10 0.00 0.00 0.00
20 0.00 0.01 0.00
100 0.01 0.02 0.08
∞ 0.03 0.07 0.58
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
60_L 96_R 2.53 0.98 0.95
85_Y 84_L 2.32 0.96 0.91
60_L 91_L 1.83 0.83 0.66
35_D 67_R 1.78 0.81 0.61
78_T 118_V 1.71 0.77 0.55
78_T 107_M 1.60 0.70 0.45
3_K 106_Q 1.48 0.61 0.34
52_Q 68_E 1.46 0.60 0.33
65_E 46_I 1.45 0.59 0.31
29_Y 77_L 1.43 0.57 0.30
48_A 97_V 1.42 0.56 0.29
67_L 105_L 1.40 0.55 0.28
70_R 61_R 1.38 0.53 0.26
76_S 107_M 1.36 0.52 0.25
75_L 110_V 1.33 0.49 0.22
53_L 113_S 1.26 0.44 0.18
85_Y 66_Q 1.26 0.43 0.17
66_A 88_E 1.24 0.42 0.17
89_P 118_V 1.22 0.40 0.15
60_L 87_E 1.20 0.39 0.14
11_I 34_R 1.16 0.36 0.12
54_F 90_A 1.16 0.36 0.12
34_D 44_I 1.16 0.35 0.12
59_D 87_E 1.15 0.35 0.12
9_L 48_L 1.14 0.34 0.11
10_A 108_Q 1.13 0.34 0.11
66_A 81_W 1.13 0.33 0.11
19_L 48_L 1.11 0.32 0.10
78_T 25_P 1.11 0.32 0.10
31_R 45_C 1.11 0.32 0.10
4_L 34_R 1.09 0.31 0.09
64_Q 106_Q 1.09 0.31 0.09
20_W 61_R 1.09 0.30 0.09
88_V 97_V 1.08 0.30 0.09
14_W 97_V 1.07 0.29 0.09
58_D 111_D 1.07 0.29 0.08
75_L 81_W 1.06 0.29 0.08
14_W 106_Q 1.06 0.28 0.08
20_W 49_T 1.05 0.28 0.08
8_L 107_M 1.04 0.28 0.08
76_S 110_V 1.04 0.28 0.08
38_A 52_T 1.04 0.28 0.08
40_Q 46_I 1.04 0.27 0.07
37_A 70_L 1.04 0.27 0.07
58_D 95_S 1.03 0.27 0.07
12_L 56_T 1.03 0.27 0.07
40_Q 102_T 1.03 0.27 0.07
86_R 83_N 1.03 0.27 0.07
78_T 103_E 1.02 0.26 0.07
25_G 54_V 1.02 0.26 0.07
37_A 98_E 1.02 0.26 0.07
36_V 117_I 1.02 0.26 0.07
31_R 37_K 1.02 0.26 0.07
38_A 74_R 1.01 0.26 0.07
36_V 29_G 1.01 0.26 0.07
11_I 76_A 1.01 0.26 0.07
28_D 77_L 1.01 0.25 0.07
38_A 25_P 1.01 0.25 0.07
16_Q 81_W 1.00 0.25 0.06
65_E 97_V 1.00 0.25 0.06
24_N 31_D 1.00 0.25 0.06
51_D 102_T 0.99 0.24 0.06
71_A 101_A 0.98 0.24 0.06
6_L 44_I 0.98 0.24 0.06
25_G 61_R 0.98 0.24 0.06
41_A 89_N 0.98 0.23 0.06
80_P 54_V 0.97 0.23 0.06
88_V 27_V 0.97 0.23 0.06
84_F 115_E 0.96 0.23 0.05
49_R 61_R 0.96 0.23 0.05
10_A 40_L 0.96 0.23 0.05
78_T 53_V 0.96 0.23 0.05
22_G 49_T 0.96 0.23 0.05
40_Q 103_E 0.95 0.22 0.05
14_W 63_L 0.95 0.22 0.05
91_A 120_Q 0.95 0.22 0.05
11_I 46_I 0.95 0.22 0.05
43_N 74_R 0.95 0.22 0.05
93_K 101_A 0.94 0.21 0.05
37_A 93_D 0.94 0.21 0.05
31_R 76_A 0.94 0.21 0.05
46_L 61_R 0.94 0.21 0.05
73_N 81_W 0.93 0.21 0.05
51_D 114_Q 0.93 0.21 0.04
30_T 118_V 0.93 0.21 0.04
37_A 51_V 0.93 0.21 0.04
88_V 108_Q 0.93 0.20 0.04
86_R 91_L 0.92 0.20 0.04
40_Q 34_R 0.92 0.20 0.04
3_K 75_D 0.92 0.20 0.04
66_A 61_R 0.92 0.20 0.04
42_T 84_L 0.91 0.20 0.04
68_E 107_M 0.91 0.20 0.04
9_L 72_L 0.91 0.20 0.04
67_L 89_N 0.91 0.20 0.04
14_W 46_I 0.91 0.20 0.04
63_G 61_R 0.91 0.20 0.04
74_E 94_H 0.90 0.19 0.04
57_I 83_N 0.90 0.19 0.04
11_I 101_A 0.90 0.19 0.04
26_I 41_C 0.90 0.19 0.04
20_W 42_L 0.90 0.19 0.04
50_N 54_V 0.90 0.19 0.04
88_V 63_L 0.89 0.19 0.04
11_I 37_K 0.89 0.19 0.04
43_N 61_R 0.89 0.19 0.04
2_G 109_H 0.89 0.19 0.04
42_T 78_D 0.89 0.18 0.04
64_Q 23_A 0.88 0.18 0.04
15_L 81_W 0.88 0.18 0.04
89_P 120_Q 0.88 0.18 0.04
72_R 84_L 0.87 0.18 0.03
80_P 119_V 0.87 0.18 0.03
34_D 45_C 0.87 0.18 0.03
92_S 30_D 0.86 0.17 0.03
34_D 32_L 0.86 0.17 0.03
90_D 101_A 0.85 0.17 0.03
31_R 48_L 0.85 0.17 0.03
81_G 105_L 0.85 0.17 0.03
8_L 105_L 0.85 0.17 0.03
18_S 117_I 0.85 0.17 0.03
4_L 44_I 0.84 0.17 0.03
66_A 85_I 0.84 0.17 0.03
66_A 31_D 0.84 0.17 0.03
60_L 94_H 0.84 0.17 0.03
65_E 63_L 0.84 0.16 0.03
9_L 111_D 0.84 0.16 0.03
84_F 64_T 0.84 0.16 0.03
41_A 51_V 0.84 0.16 0.03
23_K 82_R 0.84 0.16 0.03
70_R 88_E 0.84 0.16 0.03
60_L 88_E 0.84 0.16 0.03
37_A 103_E 0.84 0.16 0.03
76_S 55_T 0.84 0.16 0.03
67_L 91_L 0.83 0.16 0.03
18_S 67_R 0.83 0.16 0.03
58_D 97_V 0.83 0.16 0.03
43_N 87_E 0.83 0.16 0.03
81_G 29_G 0.83 0.16 0.03
35_D 27_V 0.83 0.16 0.03
77_M 42_L 0.83 0.16 0.03
46_L 66_Q 0.83 0.16 0.03
38_A 118_V 0.82 0.16 0.03
10_A 47_I 0.82 0.16 0.03
6_L 48_L 0.82 0.16 0.03
22_G 46_I 0.82 0.15 0.03
4_L 117_I 0.82 0.15 0.03
91_A 44_I 0.82 0.15 0.03
39_Q 95_S 0.82 0.15 0.03
51_D 51_V 0.82 0.15 0.03
65_E 26_G 0.81 0.15 0.03
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
14321 0.52 FtsB_FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) 0.27 Done - Shared
4023 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-06, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.95 Done - Shared
4021 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-10, 8) B:(1E-10, 8) msa: Jackhmmer (2015_06) 0.13 Done - Shared
4020 0.49 FtsB-FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) 0.05 Done - Shared
3963 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) Killed - Shared
3961 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) Killed - Shared
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