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OPENSEQ.org
FtsB-FtsL
Genes: A B A+B
Length: 103 121 197
Sequences: 955 223 122
Seq/Len: 9.27 1.84 0.62
MirrorTree (Pazo et al. 2001) 0.89
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.00 0.00 0.00
2 0.00 0.00 0.00
5 0.00 0.00 0.00
10 0.00 0.00 0.00
20 0.00 0.00 0.02
100 0.00 0.00 0.09
∞ 0.00 0.00 0.54
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
65_E 97_V 1.87 0.85 0.13
25_G 60_T 1.80 0.82 0.11
35_D 67_R 1.76 0.80 0.10
86_R 115_E 1.68 0.75 0.08
25_G 57_A 1.66 0.74 0.07
70_R 54_V 1.60 0.70 0.07
78_T 91_L 1.60 0.70 0.07
78_T 41_C 1.52 0.64 0.05
24_N 31_D 1.50 0.63 0.05
67_L 62_L 1.48 0.61 0.05
15_L 53_V 1.35 0.51 0.03
56_E 88_E 1.35 0.51 0.03
75_L 81_W 1.32 0.49 0.03
40_Q 117_I 1.29 0.46 0.03
77_M 37_K 1.28 0.45 0.03
76_S 110_V 1.28 0.45 0.03
76_S 81_W 1.25 0.43 0.02
15_L 81_W 1.24 0.42 0.02
24_N 82_R 1.21 0.39 0.02
49_R 61_R 1.19 0.38 0.02
88_V 45_C 1.18 0.37 0.02
77_M 40_L 1.17 0.37 0.02
46_L 88_E 1.17 0.36 0.02
70_R 88_E 1.16 0.36 0.02
67_L 26_G 1.12 0.33 0.01
84_F 70_L 1.12 0.33 0.01
4_L 40_L 1.12 0.33 0.01
87_L 59_H 1.12 0.33 0.01
32_V 85_I 1.12 0.33 0.01
51_D 102_T 1.10 0.32 0.01
38_A 52_T 1.10 0.31 0.01
76_S 94_H 1.10 0.31 0.01
19_L 56_T 1.09 0.31 0.01
87_L 55_T 1.08 0.30 0.01
84_F 24_L 1.07 0.29 0.01
25_G 43_F 1.06 0.29 0.01
65_E 68_E 1.06 0.29 0.01
2_G 57_A 1.05 0.28 0.01
85_Y 113_S 1.05 0.28 0.01
56_E 20_E 1.04 0.27 0.01
3_K 56_T 1.02 0.26 0.01
83_T 94_H 1.02 0.26 0.01
53_L 113_S 1.01 0.26 0.01
24_N 83_N 1.01 0.25 0.01
30_T 117_I 1.01 0.25 0.01
85_Y 60_T 1.00 0.25 0.01
34_D 27_V 1.00 0.25 0.01
7_L 117_I 1.00 0.25 0.01
78_T 53_V 0.99 0.24 0.01
69_E 61_R 0.99 0.24 0.01
55_A 98_E 0.99 0.24 0.01
39_Q 95_S 0.99 0.24 0.01
23_K 31_D 0.99 0.24 0.01
7_L 112_P 0.98 0.24 0.01
13_V 32_L 0.98 0.24 0.01
11_I 46_I 0.98 0.24 0.01
36_V 89_N 0.98 0.23 0.01
4_L 46_I 0.98 0.23 0.01
21_F 77_L 0.97 0.23 0.01
24_N 24_L 0.97 0.23 0.01
24_N 115_E 0.97 0.23 0.01
19_L 48_L 0.96 0.23 0.01
39_Q 78_D 0.96 0.23 0.01
25_G 118_V 0.95 0.22 0.01
44_A 69_Q 0.95 0.22 0.01
41_A 52_T 0.95 0.22 0.01
59_D 87_E 0.95 0.22 0.01
86_R 95_S 0.94 0.21 0.01
50_N 61_R 0.94 0.21 0.01
60_L 61_R 0.94 0.21 0.01
80_P 98_E 0.94 0.21 0.01
78_T 49_T 0.94 0.21 0.01
14_W 36_G 0.94 0.21 0.01
74_E 94_H 0.94 0.21 0.01
75_L 94_H 0.93 0.21 0.01
89_P 104_K 0.93 0.21 0.01
19_L 53_V 0.93 0.20 0.01
69_E 84_L 0.92 0.20 0.01
25_G 88_E 0.92 0.20 0.01
84_F 77_L 0.92 0.20 0.01
74_E 82_R 0.92 0.20 0.01
31_R 37_K 0.91 0.20 0.01
25_G 28_I 0.91 0.20 0.01
63_G 61_R 0.91 0.20 0.01
19_L 82_R 0.91 0.20 0.01
27_H 118_V 0.91 0.20 0.01
85_Y 21_R 0.91 0.20 0.01
78_T 40_L 0.91 0.20 0.01
43_N 96_R 0.91 0.20 0.01
73_N 118_V 0.91 0.20 0.01
15_L 46_I 0.90 0.19 0.01
75_L 61_R 0.90 0.19 0.01
53_L 81_W 0.89 0.19 0.01
93_K 119_V 0.89 0.19 0.01
61_N 102_T 0.88 0.18 0.01
89_P 20_E 0.88 0.18 0.01
79_R 41_C 0.87 0.18 0.01
13_V 69_Q 0.87 0.18 0.01
86_R 31_D 0.87 0.18 0.01
36_V 63_L 0.87 0.18 0.01
25_G 67_R 0.87 0.18 0.01
47_K 112_P 0.87 0.18 0.01
85_Y 106_Q 0.87 0.18 0.01
4_L 48_L 0.87 0.18 0.01
85_Y 118_V 0.87 0.18 0.01
83_T 110_V 0.87 0.18 0.01
87_L 23_A 0.86 0.17 0.01
53_L 35_F 0.86 0.17 0.01
78_T 27_V 0.86 0.17 0.01
76_S 82_R 0.85 0.17 0.01
93_K 23_A 0.85 0.17 0.01
83_T 109_H 0.85 0.17 0.01
76_S 107_M 0.85 0.17 0.01
36_V 62_L 0.85 0.17 0.01
61_N 52_T 0.85 0.17 0.01
63_G 82_R 0.84 0.17 0.01
24_N 78_D 0.84 0.17 0.01
70_R 74_R 0.84 0.17 0.01
56_E 86_L 0.84 0.16 0.01
30_T 57_A 0.83 0.16 0.01
57_I 31_D 0.83 0.16 0.01
48_A 112_P 0.83 0.16 0.01
85_Y 79_I 0.83 0.16 0.01
85_Y 55_T 0.82 0.16 0.01
34_D 72_L 0.82 0.16 0.01
29_Y 115_E 0.82 0.16 0.01
8_L 105_L 0.82 0.16 0.01
81_G 105_L 0.82 0.16 0.01
67_L 77_L 0.82 0.16 0.01
14_W 28_I 0.82 0.15 0.01
44_A 66_Q 0.82 0.15 0.01
74_E 95_S 0.81 0.15 0.01
18_S 60_T 0.81 0.15 0.01
37_A 97_V 0.81 0.15 0.01
2_G 22_H 0.81 0.15 0.00
22_G 70_L 0.81 0.15 0.00
28_D 115_E 0.81 0.15 0.00
75_L 91_L 0.81 0.15 0.00
26_I 22_H 0.81 0.15 0.00
15_L 55_T 0.81 0.15 0.00
85_Y 84_L 0.81 0.15 0.00
12_L 55_T 0.80 0.15 0.00
88_V 114_Q 0.80 0.15 0.00
10_A 97_V 0.80 0.15 0.00
20_W 49_T 0.80 0.15 0.00
27_H 57_A 0.80 0.15 0.00
88_V 101_A 0.80 0.15 0.00
36_V 67_R 0.80 0.15 0.00
66_A 31_D 0.80 0.14 0.00
46_L 61_R 0.80 0.14 0.00
5_T 21_R 0.80 0.14 0.00
29_Y 70_L 0.79 0.14 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
14321 0.52 FtsB_FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) 0.27 Done - Shared
4023 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-06, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.95 Done - Shared
4021 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-10, 8) B:(1E-10, 8) msa: Jackhmmer (2015_06) 0.13 Done - Shared
4020 0.49 FtsB-FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) 0.05 Done - Shared
3963 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) Killed - Shared
3961 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) Killed - Shared
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