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OPENSEQ.org
FtsB-FtsL
Genes: A B A+B
Length: 103 121 200
Sequences: 499 168 99
Seq/Len: 4.84 1.39 0.49
MirrorTree (Pazo et al. 2001) 0.85
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.00 0.00 0.00
2 0.00 0.00 0.00
5 0.00 0.00 0.00
10 0.00 0.00 0.00
20 0.00 0.00 0.00
100 0.00 0.00 0.08
∞ 0.00 0.00 0.44
Paired alignment generation
None of the genomes have hits within 20 Δgene.
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
35_D 67_R 1.86 0.79 0.05
25_G 57_A 1.79 0.75 0.04
56_E 88_E 1.67 0.68 0.03
25_G 60_T 1.60 0.63 0.02
85_Y 60_T 1.55 0.59 0.02
70_R 54_V 1.48 0.54 0.02
77_M 40_L 1.48 0.54 0.02
40_Q 117_I 1.48 0.54 0.02
75_L 81_W 1.46 0.53 0.02
78_T 41_C 1.45 0.52 0.02
15_L 53_V 1.43 0.51 0.01
4_L 46_I 1.40 0.48 0.01
85_Y 55_T 1.38 0.47 0.01
65_E 97_V 1.35 0.44 0.01
11_I 46_I 1.31 0.42 0.01
77_M 37_K 1.31 0.41 0.01
65_E 68_E 1.28 0.39 0.01
59_D 87_E 1.28 0.39 0.01
70_R 88_E 1.27 0.39 0.01
85_Y 84_L 1.23 0.35 0.01
74_E 94_H 1.20 0.33 0.01
78_T 53_V 1.20 0.33 0.01
32_V 85_I 1.19 0.33 0.01
2_G 57_A 1.19 0.33 0.01
51_D 102_T 1.18 0.32 0.01
67_L 62_L 1.18 0.32 0.01
80_P 98_E 1.17 0.32 0.01
76_S 81_W 1.16 0.31 0.01
56_E 60_T 1.16 0.31 0.01
15_L 81_W 1.15 0.30 0.01
41_A 52_T 1.15 0.30 0.01
22_G 70_L 1.15 0.30 0.01
56_E 20_E 1.13 0.28 0.01
19_L 82_R 1.12 0.28 0.01
13_V 69_Q 1.12 0.28 0.01
76_S 110_V 1.11 0.28 0.01
46_L 88_E 1.11 0.28 0.01
50_N 61_R 1.10 0.27 0.01
60_L 61_R 1.10 0.27 0.01
76_S 82_R 1.10 0.27 0.01
83_T 110_V 1.09 0.27 0.01
36_V 89_N 1.09 0.26 0.01
78_T 40_L 1.08 0.26 0.01
88_V 101_A 1.08 0.26 0.01
64_Q 100_I 1.08 0.26 0.01
86_R 115_E 1.07 0.25 0.01
67_L 80_E 1.07 0.25 0.01
88_V 100_I 1.07 0.25 0.01
84_F 24_L 1.06 0.25 0.01
4_L 97_V 1.06 0.24 0.01
19_L 56_T 1.04 0.23 0.00
38_A 52_T 1.04 0.23 0.00
88_V 56_T 1.04 0.23 0.00
85_Y 106_Q 1.04 0.23 0.00
86_R 87_E 1.03 0.23 0.00
76_S 94_H 1.03 0.23 0.00
83_T 109_H 1.03 0.23 0.00
88_V 45_C 1.02 0.22 0.00
53_L 35_F 1.02 0.22 0.00
65_E 26_G 1.01 0.22 0.00
25_G 43_F 1.00 0.21 0.00
3_K 56_T 1.00 0.21 0.00
87_L 55_T 0.99 0.21 0.00
85_Y 118_V 0.99 0.21 0.00
7_L 117_I 0.99 0.21 0.00
81_G 100_I 0.98 0.20 0.00
78_T 39_P 0.98 0.20 0.00
34_D 27_V 0.98 0.20 0.00
4_L 40_L 0.97 0.20 0.00
36_V 98_E 0.97 0.20 0.00
88_V 114_Q 0.97 0.20 0.00
8_L 107_M 0.96 0.20 0.00
27_H 57_A 0.96 0.19 0.00
10_A 103_E 0.96 0.19 0.00
11_I 101_A 0.95 0.19 0.00
66_A 31_D 0.95 0.19 0.00
83_T 57_A 0.95 0.19 0.00
79_R 41_C 0.95 0.19 0.00
31_R 37_K 0.95 0.19 0.00
21_F 79_I 0.94 0.18 0.00
52_Q 54_V 0.94 0.18 0.00
53_L 113_S 0.93 0.18 0.00
25_G 28_I 0.93 0.18 0.00
23_K 91_L 0.93 0.18 0.00
34_D 72_L 0.93 0.18 0.00
13_V 32_L 0.92 0.18 0.00
39_Q 95_S 0.92 0.17 0.00
75_L 91_L 0.92 0.17 0.00
78_T 91_L 0.92 0.17 0.00
77_M 28_I 0.91 0.17 0.00
19_L 48_L 0.91 0.17 0.00
4_L 48_L 0.91 0.17 0.00
84_F 42_L 0.90 0.17 0.00
2_G 22_H 0.90 0.17 0.00
93_K 23_A 0.90 0.17 0.00
53_L 81_W 0.90 0.17 0.00
59_D 94_H 0.90 0.17 0.00
19_L 53_V 0.90 0.16 0.00
85_Y 113_S 0.89 0.16 0.00
30_T 57_A 0.89 0.16 0.00
53_L 37_K 0.89 0.16 0.00
63_G 70_L 0.89 0.16 0.00
49_R 61_R 0.89 0.16 0.00
75_L 94_H 0.89 0.16 0.00
19_L 84_L 0.89 0.16 0.00
91_A 44_I 0.89 0.16 0.00
57_I 88_E 0.89 0.16 0.00
13_V 19_H 0.88 0.16 0.00
73_N 72_L 0.88 0.16 0.00
36_V 62_L 0.88 0.16 0.00
21_F 99_R 0.87 0.15 0.00
87_L 100_I 0.87 0.15 0.00
55_A 98_E 0.86 0.15 0.00
28_D 43_F 0.86 0.15 0.00
25_G 118_V 0.86 0.15 0.00
73_N 118_V 0.86 0.15 0.00
43_N 73_E 0.85 0.15 0.00
10_A 32_L 0.85 0.15 0.00
86_R 89_N 0.85 0.15 0.00
87_L 59_H 0.84 0.14 0.00
19_L 112_P 0.84 0.14 0.00
56_E 83_N 0.84 0.14 0.00
85_Y 90_A 0.84 0.14 0.00
87_L 23_A 0.84 0.14 0.00
6_L 44_I 0.84 0.14 0.00
57_I 90_A 0.84 0.14 0.00
86_R 95_S 0.83 0.14 0.00
12_L 55_T 0.83 0.14 0.00
51_D 55_T 0.83 0.14 0.00
37_A 112_P 0.83 0.14 0.00
14_W 44_I 0.83 0.14 0.00
65_E 66_Q 0.82 0.14 0.00
77_M 92_G 0.82 0.14 0.00
55_A 33_L 0.81 0.13 0.00
58_D 111_D 0.81 0.13 0.00
62_G 74_R 0.81 0.13 0.00
36_V 76_A 0.81 0.13 0.00
20_W 49_T 0.81 0.13 0.00
65_E 82_R 0.81 0.13 0.00
76_S 53_V 0.81 0.13 0.00
10_A 89_N 0.80 0.13 0.00
41_A 103_E 0.80 0.13 0.00
1_M 54_V 0.80 0.13 0.00
29_Y 42_L 0.80 0.13 0.00
67_L 26_G 0.80 0.13 0.00
34_D 30_D 0.80 0.13 0.00
35_D 48_L 0.80 0.13 0.00
26_I 75_D 0.80 0.13 0.00
2_G 109_H 0.79 0.13 0.00
75_L 107_M 0.79 0.12 0.00
70_R 50_A 0.79 0.12 0.00
11_I 34_R 0.79 0.12 0.00
37_A 97_V 0.79 0.12 0.00
23_K 86_L 0.79 0.12 0.00
48_A 40_L 0.79 0.12 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
14321 0.52 FtsB_FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) 0.27 Done - Shared
4023 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-06, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.95 Done - Shared
4021 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-10, 8) B:(1E-10, 8) msa: Jackhmmer (2015_06) 0.13 Done - Shared
4020 0.49 FtsB-FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) 0.05 Done - Shared
3963 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) Killed - Shared
3961 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) Killed - Shared
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