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OPENSEQ.org
cIV_B_4_cI_K_4_Pdenitr
Genes: A B A+B
Length: 252 101 328
Sequences: 4637 4825 2834
Seq/Len: 18.4 47.77 8.64
MirrorTree (Pazo et al. 2001) 0.59
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.00 0.00 0.17
2 0.00 0.00 0.31
5 0.00 0.01 2.56
10 0.01 0.01 4.92
20 0.01 0.02 5.10
100 0.02 0.03 5.53
∞ 0.04 0.07 8.03
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
176_A 93_V 0.95 0.87 0.02
195_V 43_V 0.89 0.82 0.01
236_Q 30_I 0.82 0.73 0.01
239_Y 74_A 0.81 0.72 0.01
147_A 65_F 0.80 0.71 0.01
180_I 51_S 0.79 0.70 0.01
212_Y 94_E 0.78 0.69 0.01
174_V 54_L 0.78 0.69 0.01
116_A 62_F 0.78 0.68 0.01
92_I 18_G 0.77 0.68 0.01
73_H 14_L 0.75 0.65 0.01
166_V 32_I 0.75 0.64 0.01
20_F 17_T 0.75 0.64 0.01
74_N 71_A 0.74 0.62 0.01
164_V 68_T 0.73 0.62 0.01
16_G 69_V 0.73 0.61 0.01
169_K 47_F 0.73 0.60 0.01
60_F 31_V 0.71 0.58 0.01
202_L 64_M 0.70 0.56 0.01
159_D 89_G 0.69 0.55 0.01
131_G 45_I 0.68 0.53 0.01
195_V 71_A 0.68 0.52 0.01
212_Y 25_N 0.68 0.52 0.01
172_V 65_F 0.67 0.52 0.01
59_R 22_I 0.67 0.51 0.01
239_Y 33_L 0.66 0.49 0.01
235_S 28_N 0.65 0.48 0.01
172_V 60_Q 0.65 0.48 0.01
169_K 59_G 0.65 0.48 0.01
89_L 80_I 0.65 0.47 0.01
23_A 69_V 0.64 0.47 0.01
103_S 99_M 0.64 0.46 0.01
212_Y 51_S 0.64 0.46 0.01
235_S 80_I 0.64 0.46 0.01
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
3301 8.31 cIV_B_10_cI_K_6_Pdenitr Δgene:(1, ∞) A:(1E-10, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.10 Done - Shared
3300 8.28 cIV_B_6_cI_K_6_Pdenitr Δgene:(1, ∞) A:(1E-06, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.17 Done - Shared
3299 2.61 cIV_B_6_cI_K_20_Pdenitr Δgene:(1, ∞) A:(1E-06, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) 0.00 Done - Shared
3297 7.24 cIV_B_6_cI_K_10_Pdenitr Δgene:(1, ∞) A:(1E-06, 8) B:(1E-10, 8) msa: Jackhmmer (2015_06) 0.07 Done - Shared
3296 7.26 cIV_B_4_cI_K_10_Pdenitr Δgene:(1, ∞) A:(1E-04, 8) B:(1E-10, 8) msa: Jackhmmer (2015_06) 0.07 Done - Shared
3295 8.33 cIV_B_4_cI_K_6_Pdenitr Δgene:(1, ∞) A:(1E-04, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.07 Done - Shared
3294 8.64 cIV_B_4_cI_K_4_Pdenitr Δgene:(1, ∞) A:(1E-04, 8) B:(1E-04, 8) msa: Jackhmmer (2015_06) 0.02 Done - Shared
3239 0.62 cIV_B_40_cI_K_40_Pdenitr Δgene:(1, ∞) A:(1E-40, 8) B:(1E-40, 8) msa: Jackhmmer (2015_06) 0.00 Done - Shared
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