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OPENSEQ.org
FtsB_FtsL
Genes: A B A+B
Length: 103 121 198
Sequences: 549 181 103
Seq/Len: 5.33 1.5 0.52
MirrorTree (Pazo et al. 2001) 0.84
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show HHblits results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.06 0.01 0.00
2 0.06 0.01 0.00
5 0.06 0.01 0.00
10 0.06 0.01 0.00
20 0.06 0.01 0.00
100 0.06 0.01 0.08
∞ 0.06 0.01 0.46
Paired alignment generation
None of the genomes have hits within 20 Δgene.
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
35_D 67_R 2.02 0.87 0.27
25_G 57_A 1.75 0.75 0.14
25_G 60_T 1.69 0.71 0.12
78_T 41_C 1.62 0.66 0.10
70_R 54_V 1.57 0.62 0.09
56_E 88_E 1.45 0.54 0.06
75_L 81_W 1.41 0.51 0.05
48_A 40_L 1.41 0.50 0.05
51_D 102_T 1.36 0.47 0.04
15_L 53_V 1.35 0.46 0.04
78_T 53_V 1.33 0.44 0.04
77_M 37_K 1.31 0.43 0.04
84_F 24_L 1.29 0.42 0.04
85_Y 55_T 1.28 0.40 0.04
4_L 46_I 1.26 0.39 0.03
70_R 88_E 1.26 0.39 0.03
32_V 85_I 1.25 0.38 0.03
85_Y 60_T 1.24 0.37 0.03
40_Q 117_I 1.24 0.37 0.03
88_V 45_C 1.23 0.37 0.03
83_T 110_V 1.22 0.36 0.03
15_L 81_W 1.20 0.34 0.03
22_G 70_L 1.19 0.34 0.03
59_D 87_E 1.18 0.33 0.03
80_P 98_E 1.16 0.32 0.02
50_N 61_R 1.16 0.32 0.02
60_L 61_R 1.16 0.32 0.02
19_L 56_T 1.15 0.31 0.02
75_L 91_L 1.14 0.30 0.02
76_S 81_W 1.13 0.30 0.02
13_V 69_Q 1.13 0.30 0.02
77_M 40_L 1.12 0.29 0.02
24_N 31_D 1.11 0.29 0.02
88_V 101_A 1.10 0.28 0.02
4_L 97_V 1.10 0.28 0.02
46_L 88_E 1.09 0.28 0.02
64_Q 100_I 1.09 0.28 0.02
85_Y 84_L 1.09 0.28 0.02
65_E 97_V 1.09 0.27 0.02
11_I 101_A 1.09 0.27 0.02
79_R 41_C 1.08 0.27 0.02
76_S 110_V 1.07 0.26 0.02
4_L 40_L 1.07 0.26 0.02
85_Y 118_V 1.05 0.25 0.01
38_A 52_T 1.05 0.25 0.01
81_G 100_I 1.05 0.25 0.01
52_Q 54_V 1.04 0.24 0.01
30_T 57_A 1.03 0.24 0.01
2_G 57_A 1.03 0.24 0.01
87_L 55_T 1.03 0.24 0.01
65_E 68_E 1.02 0.23 0.01
85_Y 66_Q 1.02 0.23 0.01
36_V 98_E 1.02 0.23 0.01
41_A 52_T 1.02 0.23 0.01
74_E 94_H 1.02 0.23 0.01
12_L 31_D 1.01 0.23 0.01
55_A 98_E 1.01 0.23 0.01
31_R 37_K 1.01 0.23 0.01
8_L 42_L 1.01 0.23 0.01
3_K 116_N 1.01 0.22 0.01
67_L 62_L 1.00 0.22 0.01
7_L 76_A 1.00 0.22 0.01
83_T 57_A 1.00 0.22 0.01
86_R 115_E 1.00 0.22 0.01
27_H 57_A 1.00 0.22 0.01
78_T 39_P 1.00 0.22 0.01
65_E 82_R 0.99 0.22 0.01
85_Y 106_Q 0.99 0.22 0.01
67_L 80_E 0.98 0.21 0.01
19_L 82_R 0.98 0.21 0.01
54_F 27_V 0.97 0.20 0.01
49_R 61_R 0.97 0.20 0.01
43_N 87_E 0.96 0.20 0.01
76_S 82_R 0.96 0.20 0.01
67_L 46_I 0.95 0.20 0.01
4_L 48_L 0.95 0.20 0.01
34_D 72_L 0.95 0.20 0.01
72_R 24_L 0.95 0.19 0.01
82_E 24_L 0.95 0.19 0.01
77_M 28_I 0.94 0.19 0.01
25_G 28_I 0.94 0.19 0.01
78_T 40_L 0.94 0.19 0.01
55_A 90_A 0.93 0.19 0.01
19_L 84_L 0.92 0.18 0.01
56_E 60_T 0.92 0.18 0.01
53_L 81_W 0.92 0.18 0.01
51_D 55_T 0.91 0.18 0.01
36_V 27_V 0.91 0.18 0.01
53_L 113_S 0.91 0.18 0.01
7_L 112_P 0.91 0.18 0.01
85_Y 113_S 0.91 0.18 0.01
29_Y 42_L 0.91 0.17 0.01
45_K 68_E 0.91 0.17 0.01
88_V 100_I 0.90 0.17 0.01
76_S 94_H 0.90 0.17 0.01
86_R 87_E 0.90 0.17 0.01
53_L 35_F 0.89 0.17 0.01
34_D 27_V 0.89 0.17 0.01
78_T 91_L 0.89 0.17 0.01
76_S 107_M 0.88 0.17 0.01
12_L 55_T 0.88 0.17 0.01
36_V 62_L 0.88 0.17 0.01
63_G 82_R 0.88 0.16 0.01
93_K 23_A 0.88 0.16 0.01
74_E 82_R 0.88 0.16 0.01
84_F 42_L 0.88 0.16 0.01
11_I 34_R 0.88 0.16 0.01
19_L 48_L 0.88 0.16 0.01
78_T 27_V 0.87 0.16 0.01
88_V 56_T 0.87 0.16 0.01
86_R 95_S 0.87 0.16 0.01
47_K 112_P 0.86 0.16 0.01
58_D 111_D 0.86 0.16 0.01
87_L 59_H 0.86 0.15 0.01
21_F 102_T 0.86 0.15 0.01
57_I 88_E 0.85 0.15 0.01
36_V 89_N 0.85 0.15 0.01
88_V 114_Q 0.85 0.15 0.01
25_G 43_F 0.84 0.15 0.01
58_D 28_I 0.84 0.15 0.01
14_W 28_I 0.84 0.15 0.01
83_T 109_H 0.84 0.15 0.01
2_G 22_H 0.84 0.15 0.01
14_W 80_E 0.84 0.15 0.01
11_I 46_I 0.83 0.14 0.01
34_D 30_D 0.83 0.14 0.01
63_G 24_L 0.83 0.14 0.01
39_Q 86_L 0.82 0.14 0.01
19_L 53_V 0.82 0.14 0.01
66_A 90_A 0.82 0.14 0.01
39_Q 95_S 0.82 0.14 0.01
23_K 91_L 0.82 0.14 0.01
20_W 49_T 0.82 0.14 0.01
21_F 79_I 0.82 0.14 0.01
88_V 49_T 0.82 0.14 0.01
50_N 96_R 0.82 0.14 0.01
60_L 96_R 0.82 0.14 0.01
44_A 47_I 0.81 0.14 0.01
10_A 103_E 0.81 0.14 0.01
21_F 75_D 0.81 0.14 0.01
88_V 63_L 0.81 0.14 0.01
35_D 48_L 0.81 0.14 0.01
81_G 105_L 0.81 0.14 0.01
36_V 76_A 0.81 0.14 0.01
43_N 115_E 0.80 0.13 0.01
62_G 45_C 0.80 0.13 0.01
25_G 118_V 0.80 0.13 0.01
33_N 35_F 0.80 0.13 0.01
45_K 27_V 0.80 0.13 0.01
31_R 110_V 0.79 0.13 0.01
23_K 31_D 0.79 0.13 0.01
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
14321 0.52 FtsB_FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) 0.27 Done - Shared
4023 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-06, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.95 Done - Shared
4021 0.62 FtsB-FtsL Δgene:(1, ∞) A:(1E-10, 8) B:(1E-10, 8) msa: Jackhmmer (2015_06) 0.13 Done - Shared
4020 0.49 FtsB-FtsL Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) 0.05 Done - Shared
3963 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: HHblits (2015_06) Killed - Shared
3961 0 FtsB-FtsL Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_06) Killed - Shared
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