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OPENSEQ.org

COBS - COBU
UniProt: P36561 - P0AE76
Length: 428
Sequences: 646
Seq/Len: 1.52
I_Prob: 0.02

COBS - Cobalamin synthase
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: COBS
COBU - Bifunctional adenosylcobalamin biosynthesis protein CobU
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: COBU
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
124_K 40_M 1.31 0.02
162_Y 160_Q 1.14 0.01
90_G 151_F 1.08 0.01
169_G 27_V 1.07 0.01
87_T 173_V 1.04 0.01
37_F 159_N 1.02 0.01
241_V 178_V 1.02 0.01
87_T 151_F 1.01 0.01
90_G 159_N 1.00 0.01
46_A 28_L 1.00 0.01
43_L 22_G 1.00 0.01
240_L 176_I 0.98 0.01
230_T 171_L 0.97 0.01
246_L 75_N 0.96 0.01
208_T 42_A 0.95 0.01
7_A 34_Q 0.94 0.01
8_M 86_M 0.94 0.01
66_L 165_A 0.94 0.01
162_Y 21_I 0.93 0.01
221_R 48_R 0.93 0.01
213_F 130_V 0.91 0.01
107_S 32_T 0.89 0.01
11_F 40_M 0.89 0.01
2_S 132_L 0.88 0.01
194_V 30_I 0.88 0.01
58_W 77_V 0.88 0.01
90_G 138_G 0.88 0.01
156_L 148_A 0.88 0.01
123_A 173_V 0.87 0.01
169_G 134_T 0.86 0.01
49_G 130_V 0.85 0.01
116_A 163_A 0.84 0.01
230_T 57_T 0.83 0.01
163_A 144_E 0.83 0.00
50_L 62_Q 0.82 0.00
30_Y 178_V 0.82 0.00
153_A 33_S 0.82 0.00
236_E 91_L 0.82 0.00
119_F 83_V 0.82 0.00
111_T 86_M 0.81 0.00
148_V 83_V 0.81 0.00
102_E 19_A 0.81 0.00
105_R 30_I 0.80 0.00
77_G 89_N 0.80 0.00
11_F 55_W 0.80 0.00
46_A 166_A 0.79 0.00
227_T 136_E 0.79 0.00
183_V 15_R 0.79 0.00
45_G 119_L 0.78 0.00
114_G 15_R 0.78 0.00
125_I 177_G 0.78 0.00
73_V 10_R 0.78 0.00
9_L 132_L 0.78 0.00
116_A 5_V 0.78 0.00
106_D 181_K 0.77 0.00
106_D 89_N 0.77 0.00
84_L 64_L 0.77 0.00
167_G 157_R 0.77 0.00
12_I 81_E 0.76 0.00
69_V 147_L 0.76 0.00
234_A 162_L 0.76 0.00
236_E 40_M 0.76 0.00
230_T 115_E 0.76 0.00
239_E 64_L 0.76 0.00
111_T 154_I 0.76 0.00
102_E 125_R 0.75 0.00
150_R 119_L 0.75 0.00
151_G 80_L 0.75 0.00
172_F 6_T 0.75 0.00
220_K 44_I 0.75 0.00
115_L 150_H 0.75 0.00
163_A 57_T 0.75 0.00
168_L 8_G 0.74 0.00
171_V 177_G 0.74 0.00
240_L 167_N 0.74 0.00
3_K 21_I 0.74 0.00
246_L 72_I 0.74 0.00
201_G 162_L 0.73 0.00
223_L 72_I 0.73 0.00
90_G 90_L 0.73 0.00
13_T 81_E 0.73 0.00
112_H 166_A 0.73 0.00
84_L 171_L 0.73 0.00
177_D 88_T 0.73 0.00
94_A 155_A 0.73 0.00
190_I 73_N 0.72 0.00
115_L 93_D 0.72 0.00
210_V 53_E 0.72 0.00
211_A 45_E 0.72 0.00
117_L 176_I 0.72 0.00
202_V 124_Q 0.72 0.00
107_S 157_R 0.72 0.00
172_F 5_V 0.72 0.00
18_P 66_E 0.72 0.00
151_G 131_V 0.72 0.00
85_A 136_E 0.72 0.00
169_G 138_G 0.72 0.00
55_L 118_S 0.72 0.00
111_T 169_V 0.72 0.00
239_E 89_N 0.72 0.00
192_A 79_L 0.71 0.00
92_F 151_F 0.71 0.00
61_A 5_V 0.71 0.00
149_S 52_P 0.71 0.00
131_L 166_A 0.71 0.00
37_F 119_L 0.71 0.00
215_L 88_T 0.71 0.00
170_N 151_F 0.71 0.00
210_V 63_H 0.71 0.00
209_M 49_Q 0.71 0.00
98_D 141_I 0.71 0.00
7_A 39_E 0.71 0.00
119_F 77_V 0.71 0.00
150_R 87_V 0.70 0.00
105_R 59_E 0.70 0.00
111_T 2_M 0.70 0.00
148_V 30_I 0.70 0.00
93_S 29_Y 0.70 0.00
125_I 131_V 0.70 0.00
205_M 162_L 0.70 0.00
93_S 85_T 0.70 0.00
169_G 52_P 0.70 0.00
152_T 167_N 0.70 0.00
90_G 152_R 0.70 0.00
233_A 151_F 0.70 0.00
122_L 130_V 0.70 0.00
94_A 130_V 0.70 0.00
183_V 127_P 0.69 0.00
203_A 164_A 0.69 0.00
201_G 80_L 0.69 0.00
105_R 16_H 0.69 0.00
44_L 137_V 0.69 0.00
88_C 141_I 0.69 0.00
115_L 53_E 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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