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OPENSEQ.org

DHPS - GREA
UniProt: P0AC13 - P0A6W5
Length: 440
Sequences: 295
Seq/Len: 0.68
I_Prob: 0.04

DHPS - Dihydropteroate synthase
Paralog alert: 0.13 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: DHPS
GREA - Transcription elongation factor GreA
Paralog alert: 0.45 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: GREA GREB RNK
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
198_Y 119_L 1.72 0.04
253_I 152_V 1.38 0.02
99_K 157_Y 1.34 0.01
242_C 157_Y 1.27 0.01
129_A 49_H 1.26 0.01
129_A 43_K 1.25 0.01
123_P 65_I 1.19 0.01
93_I 98_D 1.18 0.01
35_N 80_M 1.18 0.01
129_A 52_R 1.17 0.01
224_I 86_V 1.14 0.01
98_S 52_R 1.09 0.01
224_I 100_D 1.08 0.01
92_W 58_C 1.04 0.01
15_P 32_A 0.98 0.01
109_V 65_I 0.98 0.01
47_M 86_V 0.97 0.00
143_G 6_M 0.97 0.00
154_Y 121_S 0.95 0.00
122_E 157_Y 0.95 0.00
265_A 62_I 0.94 0.00
191_G 70_S 0.94 0.00
183_L 94_V 0.93 0.00
269_V 20_F 0.93 0.00
160_E 138_V 0.92 0.00
214_L 15_R 0.92 0.00
90_E 49_H 0.91 0.00
119_S 29_I 0.91 0.00
12_L 116_K 0.91 0.00
254_I 101_E 0.91 0.00
239_S 157_Y 0.90 0.00
240_L 56_G 0.90 0.00
52_A 119_L 0.90 0.00
225_G 61_R 0.89 0.00
43_H 95_L 0.89 0.00
202_A 6_M 0.88 0.00
114_I 53_E 0.88 0.00
261_E 96_N 0.88 0.00
174_Q 74_V 0.88 0.00
107_A 96_N 0.88 0.00
91_V 85_R 0.88 0.00
95_V 147_E 0.88 0.00
224_I 64_D 0.87 0.00
41_V 74_V 0.87 0.00
81_V 117_Q 0.87 0.00
207_F 80_M 0.87 0.00
146_K 6_M 0.87 0.00
142_Q 70_S 0.86 0.00
137_C 131_I 0.86 0.00
47_M 152_V 0.85 0.00
159_A 138_V 0.84 0.00
198_Y 129_G 0.84 0.00
239_S 110_D 0.84 0.00
21_L 139_V 0.84 0.00
91_V 114_D 0.84 0.00
171_R 94_V 0.83 0.00
156_D 126_I 0.83 0.00
13_S 152_V 0.83 0.00
175_A 69_L 0.83 0.00
4_F 97_L 0.83 0.00
15_P 34_A 0.82 0.00
103_I 115_F 0.82 0.00
235_R 61_R 0.82 0.00
261_E 24_V 0.82 0.00
33_T 74_V 0.82 0.00
34_H 99_S 0.81 0.00
179_K 4_I 0.81 0.00
156_D 158_L 0.81 0.00
142_Q 121_S 0.81 0.00
218_M 13_K 0.81 0.00
50_A 8_L 0.81 0.00
223_M 153_I 0.81 0.00
262_T 131_I 0.81 0.00
57_V 149_E 0.81 0.00
249_Q 118_N 0.80 0.00
242_C 68_K 0.80 0.00
261_E 6_M 0.80 0.00
112_H 131_I 0.80 0.00
235_R 22_K 0.80 0.00
193_N 136_D 0.80 0.00
153_K 16_E 0.80 0.00
168_Q 115_F 0.80 0.00
263_V 86_V 0.80 0.00
172_C 3_A 0.79 0.00
21_L 16_E 0.78 0.00
134_L 110_D 0.78 0.00
227_L 130_L 0.78 0.00
52_A 74_V 0.77 0.00
160_E 12_E 0.77 0.00
85_I 148_V 0.77 0.00
224_I 142_K 0.77 0.00
15_P 35_E 0.77 0.00
30_D 38_E 0.77 0.00
119_S 100_D 0.77 0.00
42_K 135_E 0.77 0.00
47_M 28_E 0.77 0.00
248_M 96_N 0.77 0.00
67_A 74_V 0.77 0.00
130_A 145_G 0.76 0.00
262_T 5_P 0.76 0.00
261_E 118_N 0.75 0.00
207_F 136_D 0.75 0.00
100_P 58_C 0.75 0.00
47_M 150_F 0.75 0.00
76_Q 54_Q 0.75 0.00
193_N 67_A 0.74 0.00
129_A 77_V 0.74 0.00
265_A 30_I 0.74 0.00
249_Q 85_R 0.74 0.00
103_I 32_A 0.74 0.00
253_I 105_Y 0.74 0.00
264_E 122_V 0.74 0.00
191_G 15_R 0.74 0.00
154_Y 6_M 0.74 0.00
95_V 38_E 0.74 0.00
99_K 90_A 0.74 0.00
128_A 31_A 0.74 0.00
233_S 24_V 0.73 0.00
227_L 86_V 0.73 0.00
73_E 60_G 0.73 0.00
117_I 95_L 0.73 0.00
43_H 153_I 0.73 0.00
169_I 58_C 0.73 0.00
109_V 118_N 0.73 0.00
104_R 158_L 0.73 0.00
182_L 117_Q 0.73 0.00
206_E 106_R 0.73 0.00
129_A 54_Q 0.72 0.00
52_A 13_K 0.72 0.00
117_I 4_I 0.72 0.00
52_A 64_D 0.72 0.00
46_L 72_A 0.72 0.00
52_A 22_K 0.72 0.00
107_A 54_Q 0.72 0.00
92_W 100_D 0.72 0.00
243_A 131_I 0.72 0.00
83_E 149_E 0.72 0.00
52_A 20_F 0.71 0.00
98_S 43_K 0.71 0.00
236_L 99_S 0.71 0.00
118_R 38_E 0.71 0.00
20_I 120_I 0.71 0.00
103_I 88_F 0.71 0.00
92_W 141_I 0.71 0.00
92_W 57_F 0.71 0.00
90_E 118_N 0.71 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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