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YAFF - Putative uncharacterized protein YafF
UniProt: Q2EEP9 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11772
Length: 62 (58)
Sequences: 179
Seq/Len: 3.09

YAFF
Paralog alert: 0.68 [within 20: 0.13] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_E 54_S 2.551 1.00
8_I 17_F 2.549 1.00
10_R 14_A 2.04 1.00
27_I 39_R 1.623 0.98
37_G 51_Y 1.468 0.95
8_I 41_K 1.458 0.95
39_R 42_M 1.449 0.95
41_K 51_Y 1.434 0.94
1_M 42_M 1.411 0.94
19_G 22_H 1.352 0.92
5_D 13_A 1.322 0.91
28_L 38_L 1.303 0.90
38_L 46_A 1.26 0.88
49_R 52_L 1.246 0.87
18_S 47_M 1.177 0.82
33_V 41_K 1.17 0.82
34_F 37_G 1.17 0.82
46_A 52_L 1.154 0.80
25_I 53_A 1.104 0.76
1_M 15_E 1.087 0.75
10_R 36_A 1.074 0.73
1_M 19_G 1.067 0.73
28_L 37_G 1.059 0.72
45_A 55_V 1.044 0.70
11_G 14_A 1.043 0.70
32_K 37_G 1.037 0.70
18_S 26_N 1.026 0.68
31_E 55_V 1.024 0.68
2_N 5_D 1.018 0.68
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3c1dA20.79037.40.893Contact Map0.312
2lxlA1140.906Contact Map0.217
3d5lA20.96773.50.909Contact Map0.267
3dfgA10.98393.40.91Contact Map0.305
1au1A20.83873.30.91Contact Map0.197
3oq3A10.83873.10.911Contact Map0.24
2lm0A10.96772.90.913Contact Map0.022
3a2kA20.95162.80.913Contact Map0.157
2w4lA60.43552.80.913Contact Map0.226
1b5lA10.83872.80.914Contact Map0.175

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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