| UniProt: | P78055 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13471 | ||
| Length: | 220 (216) | ||
| Sequences: | 1776 | ||
| Seq/Len: | 8.22 |
| FSAA
Paralog alert: 0.36 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: FSAA FSAB TALA TALB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 73_L | 102_E | 5.911 | 1.00 | |
| 64_T | 67_G | 4.726 | 1.00 | |
| 68_M | 86_V | 3.437 | 1.00 | |
| 69_V | 98_M | 3.204 | 1.00 | |
| 66_E | 70_N | 2.821 | 1.00 | |
| 94_A | 97_K | 2.738 | 1.00 | |
| 136_D | 172_Q | 2.69 | 1.00 | |
| 2_E | 161_K | 2.622 | 1.00 | |
| 88_V | 111_V | 2.341 | 1.00 | |
| 96_I | 108_G | 2.339 | 1.00 | |
| 205_A | 209_Q | 2.312 | 1.00 | |
| 45_Q | 48_E | 2.178 | 1.00 | |
| 9_D | 35_G | 2.112 | 1.00 | |
| 150_H | 162_V | 2.109 | 1.00 | |
| 202_A | 206_K | 2.055 | 1.00 | |
| 126_E | 161_K | 2.041 | 1.00 | |
| 15_A | 192_Q | 2.024 | 1.00 | |
| 65_A | 98_M | 2.021 | 1.00 | |
| 73_L | 98_M | 1.933 | 1.00 | |
| 97_K | 101_A | 1.916 | 1.00 | |
| 148_D | 178_L | 1.891 | 1.00 | |
| 150_H | 154_K | 1.855 | 1.00 | |
| 23_A | 122_L | 1.849 | 1.00 | |
| 189_D | 193_Q | 1.83 | 1.00 | |
| 30_S | 210_D | 1.82 | 1.00 | |
| 144_Q | 148_D | 1.764 | 1.00 | |
| 147_T | 151_Q | 1.757 | 1.00 | |
| 209_Q | 212_Q | 1.731 | 1.00 | |
| 209_Q | 213_G | 1.716 | 1.00 | |
| 117_G | 149_L | 1.702 | 1.00 | |
| 105_P | 126_E | 1.698 | 1.00 | |
| 70_N | 74_K | 1.689 | 1.00 | |
| 161_K | 183_S | 1.661 | 1.00 | |
| 11_V | 14_K | 1.654 | 1.00 | |
| 73_L | 104_I | 1.613 | 1.00 | |
| 74_K | 77_S | 1.563 | 1.00 | |
| 86_V | 96_I | 1.543 | 1.00 | |
| 114_A | 152_L | 1.488 | 1.00 | |
| 63_T | 204_V | 1.484 | 1.00 | |
| 38_P | 41_V | 1.469 | 0.99 | |
| 98_M | 102_E | 1.468 | 0.99 | |
| 143_I | 176_C | 1.459 | 0.99 | |
| 114_A | 118_L | 1.455 | 0.99 | |
| 44_P | 48_E | 1.438 | 0.99 | |
| 72_A | 99_L | 1.401 | 0.99 | |
| 10_V | 42_V | 1.382 | 0.99 | |
| 107_L | 129_A | 1.365 | 0.99 | |
| 69_V | 73_L | 1.359 | 0.99 | |
| 59_Q | 131_Y | 1.341 | 0.99 | |
| 58_A | 75_L | 1.339 | 0.99 | |
| 164_A | 167_F | 1.334 | 0.99 | |
| 202_A | 205_A | 1.315 | 0.99 | |
| 39_L | 43_L | 1.313 | 0.98 | |
| 106_T | 126_E | 1.298 | 0.98 | |
| 141_S | 144_Q | 1.292 | 0.98 | |
| 32_I | 39_L | 1.284 | 0.98 | |
| 72_A | 84_V | 1.279 | 0.98 | |
| 116_Q | 200_V | 1.275 | 0.98 | |
| 70_N | 73_L | 1.27 | 0.98 | |
| 90_A | 195_I | 1.257 | 0.98 | |
| 163_L | 183_S | 1.256 | 0.98 | |
| 65_A | 94_A | 1.253 | 0.98 | |
| 11_V | 15_A | 1.25 | 0.98 | |
| 14_K | 45_Q | 1.236 | 0.98 | |
| 71_D | 74_K | 1.235 | 0.98 | |
| 40_D | 43_L | 1.231 | 0.97 | |
| 61_M | 208_E | 1.228 | 0.97 | |
| 63_T | 91_E | 1.223 | 0.97 | |
| 10_V | 56_L | 1.218 | 0.97 | |
| 65_A | 69_V | 1.217 | 0.97 | |
| 37_K | 42_V | 1.207 | 0.97 | |
| 88_V | 108_G | 1.18 | 0.96 | |
| 107_L | 131_Y | 1.179 | 0.96 | |
| 211_W | 214_A | 1.17 | 0.96 | |
| 57_F | 107_L | 1.142 | 0.96 | |
| 63_T | 208_E | 1.141 | 0.96 | |
| 133_N | 137_A | 1.139 | 0.95 | |
| 58_A | 82_I | 1.136 | 0.95 | |
| 65_A | 91_E | 1.135 | 0.95 | |
| 164_A | 176_C | 1.128 | 0.95 | |
| 175_D | 178_L | 1.125 | 0.95 | |
| 75_L | 78_I | 1.115 | 0.95 | |
| 114_A | 148_D | 1.109 | 0.95 | |
| 118_L | 155_M | 1.105 | 0.94 | |
| 186_L | 191_A | 1.104 | 0.94 | |
| 128_V | 153_L | 1.099 | 0.94 | |
| 25_V | 46_L | 1.093 | 0.94 | |
| 111_V | 153_L | 1.089 | 0.94 | |
| 16_L | 188_L | 1.087 | 0.94 | |
| 136_D | 142_G | 1.085 | 0.94 | |
| 9_D | 12_A | 1.083 | 0.94 | |
| 115_A | 174_L | 1.082 | 0.94 | |
| 67_G | 70_N | 1.082 | 0.94 | |
| 137_A | 168_K | 1.078 | 0.93 | |
| 138_Q | 141_S | 1.07 | 0.93 | |
| 122_L | 158_P | 1.068 | 0.93 | |
| 90_A | 192_Q | 1.067 | 0.93 | |
| 56_L | 79_I | 1.058 | 0.93 | |
| 176_C | 211_W | 1.053 | 0.92 | |
| 17_S | 49_A | 1.053 | 0.92 | |
| 133_N | 168_K | 1.043 | 0.92 | |
| 118_L | 152_L | 1.036 | 0.92 | |
| 110_A | 131_Y | 1.035 | 0.91 | |
| 121_A | 153_L | 1.021 | 0.91 | |
| 59_Q | 129_A | 1.007 | 0.90 | |
| 30_S | 34_A | 1.005 | 0.90 | |
| 98_M | 101_A | 1.004 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1l6wA | 10 | 1 | 100 | 0.007 | Contact Map | 0.757 |
| 3r8rA | 20 | 0.9591 | 100 | 0.009 | Contact Map | 0.736 |
| 1vpxA | 20 | 0.9909 | 100 | 0.01 | Contact Map | 0.835 |
| 3s1xA | 5 | 0.9909 | 100 | 0.018 | Contact Map | 0.74 |
| 1wx0A | 10 | 0.9727 | 100 | 0.018 | Contact Map | 0.823 |
| 3cwnA | 2 | 0.9636 | 100 | 0.176 | Contact Map | 0.692 |
| 3m16A | 1 | 0.9636 | 100 | 0.183 | Contact Map | 0.68 |
| 3tkfA | 2 | 0.9636 | 100 | 0.183 | Contact Map | 0.736 |
| 3cq0A | 2 | 0.9636 | 100 | 0.184 | Contact Map | 0.729 |
| 3hjzA | 1 | 0.9636 | 100 | 0.186 | Contact Map | 0.708 |
Sequence Conservation (Image Generated using WebLogo v3)