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YFCI - Uncharacterized protein YfcI
UniProt: P77768 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14112
Length: 296 (295)
Sequences: 559
Seq/Len: 1.89

YFCI
Paralog alert: 0.89 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: YADD YFAD YFCI YHGA YJIP
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
84_Q 94_R 2.982 1.00
276_D 279_L 2.867 1.00
267_A 286_L 2.639 1.00
46_K 67_S 2.615 1.00
286_L 294_Q 2.599 1.00
267_A 284_T 2.309 1.00
256_M 260_H 2.281 1.00
287_S 290_D 2.216 1.00
267_A 270_M 2.149 0.99
259_K 262_E 2.128 0.99
247_A 250_L 2.076 0.99
262_E 266_I 2.066 0.99
274_G 284_T 2.049 0.99
280_V 284_T 2.043 0.99
84_Q 91_M 2.028 0.99
269_E 285_R 2.013 0.99
273_R 282_M 1.951 0.99
257_Q 261_E 1.941 0.98
251_R 257_Q 1.91 0.98
267_A 274_G 1.811 0.97
263_A 266_I 1.805 0.97
280_V 286_L 1.797 0.97
91_M 94_R 1.776 0.97
274_G 280_V 1.774 0.97
103_M 117_V 1.762 0.97
255_A 259_K 1.704 0.96
52_F 65_L 1.673 0.95
281_M 291_L 1.638 0.94
266_I 270_M 1.622 0.94
267_A 280_V 1.601 0.94
133_S 138_D 1.547 0.92
96_M 100_I 1.538 0.92
270_M 284_T 1.536 0.92
51_S 80_V 1.52 0.91
67_S 74_V 1.514 0.91
269_E 282_M 1.509 0.91
290_D 293_A 1.506 0.90
271_L 274_G 1.501 0.90
163_P 166_E 1.468 0.89
270_M 283_V 1.467 0.89
280_V 291_L 1.459 0.89
65_L 102_A 1.447 0.88
269_E 273_R 1.446 0.88
274_G 286_L 1.424 0.87
278_E 288_P 1.414 0.86
21_P 66_W 1.413 0.86
275_L 279_L 1.399 0.86
281_M 288_P 1.385 0.85
281_M 293_A 1.378 0.84
11_D 15_K 1.366 0.84
255_A 261_E 1.366 0.84
10_H 14_F 1.357 0.83
265_R 273_R 1.353 0.83
14_F 83_H 1.342 0.82
288_P 291_L 1.34 0.82
253_E 257_Q 1.339 0.82
263_A 279_L 1.329 0.81
273_R 283_V 1.324 0.81
245_T 248_D 1.324 0.81
90_L 139_E 1.317 0.81
65_L 122_F 1.302 0.79
268_Q 284_T 1.295 0.79
270_M 275_L 1.282 0.78
279_L 282_M 1.273 0.77
266_I 284_T 1.263 0.77
277_R 280_V 1.256 0.76
275_L 283_V 1.252 0.76
262_E 265_R 1.248 0.75
269_E 279_L 1.244 0.75
53_I 59_Q 1.228 0.74
284_T 291_L 1.225 0.73
101_A 104_Q 1.222 0.73
113_E 141_A 1.213 0.72
264_L 286_L 1.212 0.72
284_T 294_Q 1.203 0.71
291_L 295_S 1.2 0.71
264_L 267_A 1.197 0.71
235_R 238_Q 1.196 0.71
267_A 294_Q 1.189 0.70
178_L 181_K 1.188 0.70
291_L 294_Q 1.186 0.70
24_A 32_L 1.178 0.69
284_T 287_S 1.177 0.69
282_M 294_Q 1.169 0.68
280_V 285_R 1.166 0.68
118_L 155_P 1.164 0.68
15_K 127_R 1.154 0.67
284_T 290_D 1.153 0.67
241_E 244_M 1.137 0.65
99_S 119_P 1.136 0.65
282_M 291_L 1.136 0.65
277_R 291_L 1.133 0.65
70_T 73_G 1.132 0.65
272_D 276_D 1.132 0.65
83_H 124_H 1.124 0.64
13_V 84_Q 1.123 0.64
93_F 100_I 1.118 0.63
273_R 279_L 1.118 0.63
123_Y 158_D 1.117 0.63
280_V 290_D 1.115 0.63
122_F 136_W 1.112 0.63
173_M 209_L 1.112 0.63
288_P 292_I 1.11 0.62
75_G 105_N 1.109 0.62
93_F 107_L 1.104 0.62
84_Q 106_H 1.094 0.61
78_Y 121_L 1.086 0.60
86_K 94_R 1.082 0.60
265_R 270_M 1.076 0.59
15_K 23_T 1.074 0.59
44_T 69_K 1.069 0.58
21_P 64_L 1.069 0.58
42_L 54_D 1.066 0.58
112_K 142_E 1.063 0.57
271_L 280_V 1.063 0.57
221_D 249_R 1.062 0.57
268_Q 280_V 1.053 0.56
84_Q 124_H 1.052 0.56
281_M 285_R 1.052 0.56
104_Q 108_D 1.046 0.56
276_D 291_L 1.041 0.55
47_L 66_W 1.04 0.55
267_A 290_D 1.04 0.55
56_D 104_Q 1.037 0.55
24_A 62_S 1.036 0.55
76_Y 115_P 1.034 0.54
175_L 179_I 1.032 0.54
172_K 175_L 1.03 0.54
27_F 31_H 1.029 0.54
103_M 130_Y 1.024 0.53
244_M 248_D 1.02 0.53
32_L 36_L 1.017 0.52
264_L 277_R 1.015 0.52
226_R 278_E 1.008 0.52
209_L 217_L 1.008 0.52
87_P 131_P 1.007 0.51
103_M 136_W 1.007 0.51
52_F 106_H 1.006 0.51
76_Y 91_M 1.004 0.51
54_D 61_Y 1.004 0.51
132_Y 154_F 1.003 0.51
100_I 104_Q 1.003 0.51
267_A 276_D 1.003 0.51
60_Y 94_R 1 0.51
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1jkoC10.145329.10.957Contact Map0.395
2x48A30.172321.70.959Contact Map0.541
4dyqA20.1689210.96Contact Map0.427
2cobA10.155420.20.96Contact Map0.434
2jpcA10.118219.70.96Contact Map0.429
1tc3C10.1453180.961Contact Map0.432
1hx8A20.206114.70.962Contact Map0.203
3e3vA10.371614.10.963Contact Map0.322
1j9iA20.081113.70.963Contact Map0.627
1g8eA20.199313.60.963Contact Map0.355

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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