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SUFB - FeS cluster assembly protein SufB
UniProt: P77522 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13965
Length: 495 (463)
Sequences: 1394
Seq/Len: 3.01
SUFB
Paralog alert: 0.42 [within 20: 0.25] - ratio of genomes with paralogs
Cluster includes: SUFB SUFD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
213_K 244_E 5.027 1.00
275_K 310_E 4.74 1.00
311_N 338_N 4.531 1.00
242_A 246_S 4.383 1.00
64_Y 68_L 4.18 1.00
305_A 314_M 3.699 1.00
271_V 279_V 3.654 1.00
54_E 58_E 3.603 1.00
242_A 279_V 3.44 1.00
244_E 275_K 3.275 1.00
276_N 311_N 3.139 1.00
85_Y 195_F 3.121 1.00
40_E 44_R 2.974 1.00
454_S 457_D 2.957 1.00
216_R 247_Y 2.868 1.00
36_K 87_D 2.81 1.00
213_K 243_D 2.772 1.00
367_N 398_N 2.688 1.00
51_N 174_H 2.684 1.00
245_D 276_N 2.653 1.00
337_D 367_N 2.629 1.00
307_C 312_S 2.561 1.00
273_I 314_M 2.526 1.00
337_D 366_K 2.499 1.00
34_L 45_A 2.463 1.00
210_Y 243_D 2.42 1.00
157_E 161_E 2.416 1.00
56_M 173_I 2.406 1.00
39_N 42_V 2.268 1.00
84_N 87_D 2.206 1.00
242_A 277_A 2.18 1.00
122_E 125_A 2.167 1.00
186_T 272_I 2.127 1.00
247_Y 278_E 2.118 1.00
63_A 200_A 2.045 1.00
335_R 364_I 2.019 1.00
306_L 335_R 2.003 1.00
44_R 57_L 2.002 1.00
273_I 277_A 1.995 1.00
363_H 370_S 1.992 1.00
168_S 171_E 1.964 1.00
166_F 209_I 1.943 1.00
340_I 369_K 1.923 0.99
383_Q 415_G 1.922 0.99
246_S 279_V 1.911 0.99
449_L 455_E 1.91 0.99
398_N 428_S 1.905 0.99
364_I 393_M 1.904 0.99
182_K 274_H 1.878 0.99
244_E 274_H 1.86 0.99
44_R 48_A 1.844 0.99
338_N 367_N 1.812 0.99
45_A 49_K 1.792 0.99
308_E 312_S 1.783 0.99
310_E 338_N 1.744 0.99
308_E 335_R 1.739 0.99
310_E 337_D 1.733 0.99
40_E 65_R 1.731 0.99
187_V 272_I 1.708 0.98
399_A 429_A 1.706 0.98
72_E 80_Y 1.705 0.98
199_N 237_R 1.689 0.98
65_R 69_E 1.658 0.98
349_T 382_S 1.634 0.98
158_K 161_E 1.58 0.97
273_I 279_V 1.58 0.97
275_K 309_G 1.579 0.97
66_A 69_E 1.579 0.97
242_A 248_V 1.576 0.97
395_T 426_N 1.562 0.97
45_A 48_A 1.561 0.97
397_T 428_S 1.56 0.97
128_E 137_G 1.554 0.97
65_R 68_L 1.553 0.97
339_S 365_G 1.55 0.97
59_F 200_A 1.549 0.97
125_A 128_E 1.546 0.97
424_C 431_L 1.535 0.96
337_D 365_G 1.516 0.96
21_Y 24_G 1.512 0.96
165_I 210_Y 1.496 0.96
248_V 279_V 1.495 0.96
31_T 92_S 1.493 0.96
33_E 92_S 1.486 0.95
169_F 173_I 1.485 0.95
347_A 376_G 1.462 0.95
392_I 431_L 1.459 0.95
55_W 181_R 1.449 0.95
349_T 355_A 1.446 0.94
385_S 419_F 1.437 0.94
157_E 160_A 1.42 0.94
278_E 313_K 1.396 0.93
91_Y 94_P 1.395 0.93
66_A 70_M 1.345 0.91
33_E 89_S 1.344 0.91
352_H 381_H 1.339 0.91
313_K 340_I 1.335 0.91
381_H 413_N 1.333 0.91
383_Q 417_H 1.331 0.91
119_L 124_E 1.331 0.91
39_N 49_K 1.328 0.90
372_I 390_V 1.323 0.90
392_I 424_C 1.32 0.90
36_K 89_S 1.318 0.90
440_I 462_I 1.314 0.90
31_T 229_A 1.304 0.89
66_A 190_G 1.304 0.89
39_N 64_Y 1.301 0.89
214_G 245_D 1.3 0.89
164_I 211_V 1.296 0.89
41_E 44_R 1.282 0.88
323_S 326_T 1.266 0.87
307_C 332_C 1.265 0.87
453_I 461_M 1.253 0.87
362_I 393_M 1.251 0.87
402_F 432_E 1.232 0.85
33_E 45_A 1.222 0.85
461_M 471_F 1.218 0.84
20_N 292_N 1.211 0.84
424_C 429_A 1.199 0.83
34_L 42_V 1.192 0.83
165_I 179_L 1.19 0.83
397_T 426_N 1.188 0.82
62_N 65_R 1.18 0.82
34_L 48_A 1.167 0.81
396_A 399_A 1.162 0.80
33_E 487_A 1.159 0.80
173_I 180_V 1.153 0.80
169_F 180_V 1.136 0.78
170_G 205_D 1.134 0.78
222_S 253_G 1.129 0.78
45_A 424_C 1.127 0.78
26_F 31_T 1.123 0.77
220_E 249_S 1.12 0.77
378_S 382_S 1.112 0.76
188_V 268_V 1.109 0.76
27_T 126_A 1.108 0.76
20_N 30_A 1.107 0.76
241_V 272_I 1.098 0.75
211_V 246_S 1.097 0.75
26_F 33_E 1.097 0.75
121_K 125_A 1.096 0.75
221_L 248_V 1.091 0.74
240_L 250_Y 1.091 0.74
392_I 399_A 1.087 0.74
455_E 459_I 1.086 0.74
332_C 341_G 1.085 0.74
440_I 447_Y 1.082 0.73
28_Q 397_T 1.071 0.72
199_N 268_V 1.07 0.72
334_L 368_T 1.068 0.72
48_A 57_L 1.063 0.72
168_S 205_D 1.055 0.71
366_K 397_T 1.05 0.70
33_E 385_S 1.05 0.70
276_N 338_N 1.049 0.70
40_E 48_A 1.048 0.70
244_E 276_N 1.048 0.70
27_T 146_F 1.041 0.69
32_D 49_K 1.04 0.69
225_F 254_C 1.039 0.69
422_V 431_L 1.033 0.68
249_S 282_S 1.03 0.68
22_K 27_T 1.03 0.68
312_S 332_C 1.029 0.68
42_V 45_A 1.029 0.68
51_N 276_N 1.029 0.68
103_C 106_E 1.027 0.68
121_K 124_E 1.026 0.68
48_A 65_R 1.025 0.68
340_I 371_T 1.025 0.68
22_K 25_F 1.023 0.67
271_V 314_M 1.022 0.67
35_A 42_V 1.016 0.67
162_Q 211_V 1.016 0.67
244_E 310_E 1.01 0.66
22_K 33_E 1.008 0.66
405_C 418_T 1.004 0.65
309_G 312_S 1.004 0.65
448_C 489_S 1.003 0.65
354_Q 385_S 1.001 0.65
164_I 410_I 1.001 0.65
293_N 352_H 1.001 0.65
185_G 270_E 1 0.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4dn7A20.86461000.32Contact Map0.766
1vh4A20.84241000.348Contact Map0.707
3dqqA20.153528.90.979Contact Map0.461
1rq8A10.111125.80.98Contact Map0
1yzyA20.141425.40.98Contact Map0.605
1ifyA10.086917.20.981Contact Map0.51
1jo0A20.113113.50.982Contact Map0
4mxnA40.454512.60.982Contact Map0.174
1wjiA10.1131110.983Contact Map0.715
2ekkA10.0949100.983Contact Map0.764
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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