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YBBM - UPF0014 inner membrane protein YbbM
UniProt: P77307 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13260
Length: 259 (252)
Sequences: 575
Seq/Len: 2.28
YBBM
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
50_V 197_L 3.724 1.00
152_E 155_Q 3.083 1.00
246_N 250_Q 2.495 1.00
129_M 200_M 2.314 1.00
25_S 30_L 2.211 1.00
6_I 10_S 2.153 1.00
70_V 127_A 2.048 0.99
143_N 180_A 2.025 0.99
165_T 168_Q 1.845 0.98
96_F 100_T 1.771 0.98
48_I 215_I 1.761 0.98
129_M 196_S 1.658 0.96
66_T 120_P 1.648 0.96
159_K 164_A 1.633 0.96
138_V 232_S 1.614 0.96
122_Q 204_L 1.596 0.95
25_S 33_E 1.571 0.95
76_N 194_L 1.563 0.95
141_C 237_C 1.525 0.94
73_I 131_A 1.472 0.92
58_F 202_S 1.386 0.88
201_M 222_T 1.373 0.88
204_L 217_Y 1.365 0.87
200_M 205_I 1.351 0.87
204_L 209_I 1.348 0.87
90_K 99_I 1.347 0.86
99_I 102_G 1.346 0.86
73_I 77_A 1.33 0.86
136_V 187_D 1.329 0.85
201_M 205_I 1.313 0.85
76_N 191_T 1.31 0.84
49_I 53_V 1.301 0.84
18_V 40_V 1.3 0.84
202_S 205_I 1.295 0.83
117_E 204_L 1.289 0.83
149_V 170_S 1.288 0.83
195_V 200_M 1.28 0.82
196_S 200_M 1.275 0.82
73_I 211_P 1.275 0.82
131_A 196_S 1.268 0.82
136_V 140_L 1.265 0.81
50_V 194_L 1.261 0.81
194_L 221_V 1.252 0.80
148_R 152_E 1.249 0.80
15_L 19_V 1.234 0.79
66_T 135_M 1.231 0.79
197_L 202_S 1.23 0.79
98_A 107_L 1.222 0.78
166_P 246_N 1.219 0.78
144_N 148_R 1.213 0.77
187_D 190_K 1.21 0.77
39_S 44_I 1.202 0.77
210_D 221_V 1.195 0.76
37_L 41_G 1.195 0.76
191_T 197_L 1.191 0.76
144_N 180_A 1.185 0.75
133_N 225_L 1.18 0.75
124_I 239_L 1.18 0.75
68_L 72_F 1.173 0.74
84_R 251_L 1.165 0.73
221_V 224_M 1.147 0.72
43_A 181_A 1.144 0.71
202_S 225_L 1.143 0.71
187_D 204_L 1.134 0.70
47_L 128_G 1.133 0.70
154_Q 158_E 1.133 0.70
171_A 175_R 1.131 0.70
75_F 105_I 1.128 0.70
51_G 215_I 1.127 0.70
189_A 226_L 1.127 0.70
178_I 182_L 1.126 0.70
55_K 212_V 1.125 0.70
17_L 84_R 1.125 0.70
133_N 195_V 1.12 0.69
62_D 231_L 1.115 0.69
193_G 199_G 1.113 0.68
147_Q 152_E 1.112 0.68
190_K 250_Q 1.11 0.68
129_M 225_L 1.11 0.68
70_V 228_T 1.109 0.68
45_I 108_A 1.107 0.68
72_F 112_L 1.106 0.68
44_I 219_I 1.099 0.67
17_L 175_R 1.098 0.67
192_V 222_T 1.097 0.67
63_A 221_V 1.088 0.66
46_Q 193_G 1.083 0.65
197_L 215_I 1.08 0.65
129_M 202_S 1.078 0.65
202_S 206_F 1.077 0.65
129_M 205_I 1.071 0.64
97_I 101_V 1.07 0.64
191_T 196_S 1.069 0.64
35_D 131_A 1.068 0.64
187_D 191_T 1.066 0.64
137_A 221_V 1.063 0.63
69_M 210_D 1.061 0.63
48_I 164_A 1.06 0.63
145_L 149_V 1.058 0.63
17_L 103_A 1.058 0.63
195_V 217_Y 1.054 0.62
29_K 247_S 1.053 0.62
74_C 126_I 1.051 0.62
200_M 217_Y 1.051 0.62
137_A 181_A 1.049 0.62
142_Y 201_M 1.046 0.61
22_I 37_L 1.045 0.61
197_L 204_L 1.044 0.61
53_V 135_M 1.041 0.61
129_M 201_M 1.036 0.60
58_F 211_P 1.036 0.60
130_I 180_A 1.034 0.60
73_I 76_N 1.033 0.60
5_N 59_S 1.03 0.60
9_E 179_R 1.026 0.59
55_K 210_D 1.025 0.59
130_I 228_T 1.024 0.59
39_S 67_L 1.021 0.59
177_S 206_F 1.018 0.58
32_L 60_V 1.017 0.58
50_V 225_L 1.016 0.58
246_N 252_V 1.015 0.58
167_K 241_Y 1.011 0.57
30_L 58_F 1.01 0.57
8_N 62_D 1.008 0.57
78_A 210_D 1.006 0.57
38_W 41_G 1.004 0.57
152_E 173_L 1.003 0.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3tuiA40.803172.80.946Contact Map0.285
2onkC40.9112550.952Contact Map0.313
3aqpA20.768354.30.952Contact Map0.164
3ne5A10.799251.50.953Contact Map0.23
3d31C20.907342.50.955Contact Map0.356
4k0jA60.776117.60.963Contact Map0.203
3w9iA60.779915.10.964Contact Map0.2
4dx5A30.772214.80.964Contact Map0.221
3rlfF10.903511.80.966Contact Map0.312
3rlfG10.7529100.967Contact Map0.297
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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