| UniProt: | P76341 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14046 | ||
| Length: | 137 (115) | ||
| Sequences: | 681 | ||
| Seq/Len: | 5.92 |
| HIUH
Paralog alert: 0.10 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 33_I | 45_V | 2.859 | 1.00 | |
| 115_K | 118_E | 2.426 | 1.00 | |
| 86_R | 110_E | 2.387 | 1.00 | |
| 42_A | 45_V | 2.317 | 1.00 | |
| 68_D | 137_S | 2.143 | 1.00 | |
| 57_W | 86_R | 2.113 | 1.00 | |
| 66_D | 72_K | 2.034 | 1.00 | |
| 48_T | 90_K | 1.992 | 1.00 | |
| 44_D | 64_K | 1.78 | 1.00 | |
| 86_R | 108_P | 1.712 | 1.00 | |
| 103_F | 122_V | 1.702 | 1.00 | |
| 71_I | 74_L | 1.694 | 1.00 | |
| 101_E | 114_N | 1.691 | 1.00 | |
| 90_K | 93_D | 1.683 | 1.00 | |
| 35_N | 38_T | 1.624 | 1.00 | |
| 50_E | 88_V | 1.611 | 0.99 | |
| 87_V | 122_V | 1.58 | 0.99 | |
| 30_S | 73_A | 1.545 | 0.99 | |
| 31_V | 87_V | 1.516 | 0.99 | |
| 52_K | 57_W | 1.439 | 0.99 | |
| 48_T | 62_T | 1.437 | 0.99 | |
| 36_Q | 130_G | 1.436 | 0.99 | |
| 46_T | 90_K | 1.424 | 0.98 | |
| 127_S | 130_G | 1.397 | 0.98 | |
| 63_A | 71_I | 1.378 | 0.98 | |
| 68_D | 122_V | 1.362 | 0.98 | |
| 30_S | 75_W | 1.323 | 0.97 | |
| 93_D | 96_K | 1.296 | 0.97 | |
| 46_T | 64_K | 1.296 | 0.97 | |
| 88_V | 106_E | 1.26 | 0.96 | |
| 68_D | 125_L | 1.21 | 0.95 | |
| 50_E | 59_Q | 1.165 | 0.93 | |
| 36_Q | 125_L | 1.162 | 0.93 | |
| 56_G | 97_K | 1.149 | 0.92 | |
| 40_K | 45_V | 1.129 | 0.91 | |
| 104_F | 108_P | 1.126 | 0.91 | |
| 38_T | 94_Y | 1.113 | 0.91 | |
| 32_H | 70_R | 1.101 | 0.90 | |
| 58_L | 67_K | 1.099 | 0.90 | |
| 66_D | 71_I | 1.097 | 0.90 | |
| 91_T | 107_I | 1.087 | 0.89 | |
| 46_T | 62_T | 1.086 | 0.89 | |
| 45_V | 95_F | 1.086 | 0.89 | |
| 95_F | 107_I | 1.083 | 0.89 | |
| 34_L | 70_R | 1.066 | 0.88 | |
| 89_F | 124_L | 1.066 | 0.88 | |
| 36_Q | 68_D | 1.066 | 0.88 | |
| 47_V | 87_V | 1.062 | 0.88 | |
| 95_F | 126_L | 1.057 | 0.87 | |
| 32_H | 121_H | 1.051 | 0.87 | |
| 56_G | 81_T | 1.038 | 0.86 | |
| 53_A | 56_G | 1.029 | 0.85 | |
| 43_A | 47_V | 1.019 | 0.85 | |
| 51_K | 58_L | 1.016 | 0.84 | |
| 45_V | 65_T | 1.013 | 0.84 | |
| 38_T | 98_Q | 1.013 | 0.84 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3iwvA | 4 | 0.9927 | 100 | 0.114 | Contact Map | 0.669 |
| 2g2nA | 4 | 0.8321 | 100 | 0.145 | Contact Map | 0.696 |
| 2h0eA | 2 | 0.8467 | 100 | 0.185 | Contact Map | 0.675 |
| 3qvaA | 4 | 0.8394 | 100 | 0.203 | Contact Map | 0.611 |
| 1oo2A | 4 | 0.8175 | 100 | 0.208 | Contact Map | 0.69 |
| 1f86A | 2 | 0.8102 | 100 | 0.21 | Contact Map | 0.66 |
| 4ankA | 2 | 0.9927 | 100 | 0.212 | Contact Map | 0.62 |
| 2h4eA | 2 | 0.8759 | 100 | 0.217 | Contact Map | 0.631 |
| 3e8vA | 1 | 0.5985 | 95.5 | 0.878 | Contact Map | 0.572 |
| 2ww8A | 1 | 0.8905 | 89.1 | 0.902 | Contact Map | 0.341 |
Sequence Conservation (Image Generated using WebLogo v3)