| UniProt: | P76204 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13981 | ||
| Length: | 237 (225) | ||
| Sequences: | 12365 | ||
| Seq/Len: | 54.96 |
| YDIV
Paralog alert: 0.90 [within 20: 0.47] - ratio of genomes with paralogs Cluster includes: ADRB CSRD DOSP GMR RTN YAHA YCGF YCGG YDIV YHJH YHJK YJCC YLAB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 28_V | 231_I | 3.783 | 1.00 | |
| 21_N | 218_L | 3.571 | 1.00 | |
| 62_S | 90_V | 3.134 | 1.00 | |
| 166_K | 170_Q | 3.117 | 1.00 | |
| 134_S | 160_T | 3.057 | 1.00 | |
| 111_E | 161_R | 2.849 | 1.00 | |
| 209_Q | 213_F | 2.543 | 1.00 | |
| 15_F | 70_S | 2.485 | 1.00 | |
| 204_A | 208_A | 2.474 | 1.00 | |
| 63_E | 99_N | 2.462 | 1.00 | |
| 190_S | 216_H | 2.415 | 1.00 | |
| 101_A | 136_V | 2.283 | 1.00 | |
| 140_V | 161_R | 2.266 | 1.00 | |
| 207_L | 223_W | 2.183 | 1.00 | |
| 72_Q | 76_I | 2.16 | 1.00 | |
| 36_S | 41_V | 2.13 | 1.00 | |
| 203_T | 206_I | 2.114 | 1.00 | |
| 75_F | 109_F | 2.084 | 1.00 | |
| 183_R | 191_P | 2.073 | 1.00 | |
| 155_F | 178_F | 2.064 | 1.00 | |
| 207_L | 218_L | 2.056 | 1.00 | |
| 201_I | 218_L | 1.982 | 1.00 | |
| 18_I | 217_A | 1.969 | 1.00 | |
| 166_K | 200_G | 1.946 | 1.00 | |
| 12_D | 35_S | 1.934 | 1.00 | |
| 111_E | 140_V | 1.922 | 1.00 | |
| 38_D | 41_V | 1.813 | 1.00 | |
| 52_L | 61_F | 1.805 | 1.00 | |
| 130_L | 139_L | 1.798 | 1.00 | |
| 161_R | 197_I | 1.776 | 1.00 | |
| 35_S | 42_R | 1.776 | 1.00 | |
| 179_E | 209_Q | 1.772 | 1.00 | |
| 36_S | 39_G | 1.749 | 1.00 | |
| 18_I | 161_R | 1.734 | 1.00 | |
| 19_R | 223_W | 1.686 | 1.00 | |
| 173_I | 205_E | 1.683 | 1.00 | |
| 81_F | 138_P | 1.674 | 1.00 | |
| 103_E | 107_Y | 1.666 | 1.00 | |
| 138_P | 160_T | 1.661 | 1.00 | |
| 14_Y | 227_P | 1.66 | 1.00 | |
| 70_S | 228_I | 1.654 | 1.00 | |
| 207_L | 211_T | 1.641 | 1.00 | |
| 183_R | 213_F | 1.593 | 1.00 | |
| 204_A | 222_L | 1.593 | 1.00 | |
| 32_T | 65_L | 1.588 | 1.00 | |
| 18_I | 111_E | 1.561 | 1.00 | |
| 207_L | 222_L | 1.542 | 1.00 | |
| 227_P | 230_Q | 1.525 | 1.00 | |
| 221_C | 225_A | 1.494 | 1.00 | |
| 162_V | 189_I | 1.49 | 1.00 | |
| 186_Q | 213_F | 1.49 | 1.00 | |
| 195_C | 217_A | 1.486 | 1.00 | |
| 26_V | 217_A | 1.483 | 1.00 | |
| 173_I | 179_E | 1.474 | 1.00 | |
| 14_Y | 42_R | 1.463 | 1.00 | |
| 198_A | 215_F | 1.456 | 1.00 | |
| 81_F | 111_E | 1.433 | 1.00 | |
| 86_L | 112_L | 1.429 | 1.00 | |
| 195_C | 216_H | 1.374 | 0.99 | |
| 173_I | 206_I | 1.374 | 0.99 | |
| 186_Q | 215_F | 1.363 | 0.99 | |
| 66_E | 69_K | 1.344 | 0.99 | |
| 18_I | 27_G | 1.333 | 0.99 | |
| 66_E | 70_S | 1.33 | 0.99 | |
| 86_L | 96_E | 1.322 | 0.99 | |
| 68_L | 103_E | 1.32 | 0.99 | |
| 183_R | 187_A | 1.311 | 0.99 | |
| 111_E | 138_P | 1.309 | 0.99 | |
| 141_L | 159_F | 1.308 | 0.99 | |
| 70_S | 74_F | 1.308 | 0.99 | |
| 13_C | 65_L | 1.286 | 0.99 | |
| 226_V | 234_L | 1.266 | 0.99 | |
| 32_T | 61_F | 1.258 | 0.99 | |
| 172_Q | 209_Q | 1.257 | 0.99 | |
| 83_W | 111_E | 1.245 | 0.98 | |
| 25_L | 234_L | 1.239 | 0.98 | |
| 218_L | 223_W | 1.223 | 0.98 | |
| 13_C | 64_Q | 1.222 | 0.98 | |
| 173_I | 209_Q | 1.216 | 0.98 | |
| 74_F | 228_I | 1.212 | 0.98 | |
| 127_N | 156_D | 1.196 | 0.98 | |
| 20_D | 24_V | 1.18 | 0.98 | |
| 230_Q | 233_T | 1.176 | 0.98 | |
| 18_I | 83_W | 1.174 | 0.98 | |
| 172_Q | 182_I | 1.171 | 0.98 | |
| 155_F | 171_Q | 1.16 | 0.97 | |
| 208_A | 211_T | 1.148 | 0.97 | |
| 173_I | 203_T | 1.124 | 0.97 | |
| 67_L | 82_A | 1.12 | 0.96 | |
| 161_R | 195_C | 1.118 | 0.96 | |
| 32_T | 64_Q | 1.115 | 0.96 | |
| 208_A | 212_P | 1.114 | 0.96 | |
| 175_H | 178_F | 1.108 | 0.96 | |
| 189_I | 196_I | 1.096 | 0.96 | |
| 131_L | 135_Q | 1.096 | 0.96 | |
| 129_G | 132_S | 1.084 | 0.96 | |
| 39_G | 47_R | 1.082 | 0.96 | |
| 112_L | 137_Y | 1.082 | 0.96 | |
| 180_P | 191_P | 1.075 | 0.95 | |
| 101_A | 132_S | 1.073 | 0.95 | |
| 12_D | 42_R | 1.07 | 0.95 | |
| 92_T | 121_L | 1.057 | 0.95 | |
| 15_F | 30_L | 1.056 | 0.95 | |
| 122_N | 125_K | 1.054 | 0.95 | |
| 77_Q | 232_T | 1.051 | 0.94 | |
| 159_F | 194_N | 1.05 | 0.94 | |
| 71_C | 82_A | 1.05 | 0.94 | |
| 71_C | 75_F | 1.048 | 0.94 | |
| 23_Q | 211_T | 1.043 | 0.94 | |
| 127_N | 131_L | 1.04 | 0.94 | |
| 30_L | 82_A | 1.026 | 0.94 | |
| 20_D | 26_V | 1.02 | 0.93 | |
| 187_A | 191_P | 1.009 | 0.93 | |
| 123_E | 157_G | 1.009 | 0.93 | |
| 70_S | 73_H | 1.009 | 0.93 | |
| 102_G | 106_K | 1.007 | 0.93 | |
| 186_Q | 196_I | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4hjfA | 1 | 0.9958 | 100 | -0.008 | Contact Map | 0.618 |
| 4hu4A | 2 | 0.9958 | 100 | 0.003 | Contact Map | 0.775 |
| 2r6oA | 2 | 0.9958 | 100 | 0.025 | Contact Map | 0.768 |
| 3sy8A | 4 | 0.9958 | 100 | 0.037 | Contact Map | 0.794 |
| 3hvbA | 2 | 0.9916 | 100 | 0.041 | Contact Map | 0.692 |
| 3s83A | 1 | 0.9958 | 100 | 0.051 | Contact Map | 0.648 |
| 3pjxA | 1 | 0.9409 | 100 | 0.057 | Contact Map | 0.698 |
| 4fojA | 1 | 0.9789 | 100 | 0.071 | Contact Map | 0.678 |
| 3hv8A | 1 | 0.9916 | 100 | 0.072 | Contact Map | 0.693 |
| 3tlqA | 2 | 0.9958 | 100 | 0.099 | Contact Map | 0.64 |
Sequence Conservation (Image Generated using WebLogo v3)