| UniProt: | P76004 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13894 | ||
| Length: | 219 (206) | ||
| Sequences: | 3714 | ||
| Seq/Len: | 18.03 |
| YCGM
Paralog alert: 0.54 [within 20: 0.06] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 153_N | 203_D | 4.762 | 1.00 | |
| 99_A | 189_L | 3.658 | 1.00 | |
| 147_T | 159_Q | 3.568 | 1.00 | |
| 90_R | 93_I | 3.152 | 1.00 | |
| 149_S | 208_T | 3.033 | 1.00 | |
| 151_S | 156_Q | 3.029 | 1.00 | |
| 85_T | 88_H | 2.998 | 1.00 | |
| 81_L | 84_A | 2.908 | 1.00 | |
| 74_A | 99_A | 2.866 | 1.00 | |
| 86_E | 171_P | 2.794 | 1.00 | |
| 86_E | 174_A | 2.607 | 1.00 | |
| 168_K | 171_P | 2.583 | 1.00 | |
| 71_V | 150_L | 2.502 | 1.00 | |
| 84_A | 92_A | 2.5 | 1.00 | |
| 71_V | 207_V | 2.463 | 1.00 | |
| 151_S | 206_T | 2.45 | 1.00 | |
| 125_D | 181_T | 2.434 | 1.00 | |
| 81_L | 92_A | 2.382 | 1.00 | |
| 88_H | 91_K | 2.331 | 1.00 | |
| 149_S | 159_Q | 2.313 | 1.00 | |
| 156_Q | 159_Q | 2.222 | 1.00 | |
| 47_P | 123_A | 2.061 | 1.00 | |
| 206_T | 215_T | 2.056 | 1.00 | |
| 160_G | 164_D | 1.972 | 1.00 | |
| 130_L | 187_V | 1.972 | 1.00 | |
| 151_S | 208_T | 1.944 | 1.00 | |
| 80_T | 183_K | 1.941 | 1.00 | |
| 74_A | 97_G | 1.914 | 1.00 | |
| 147_T | 161_T | 1.913 | 1.00 | |
| 147_T | 210_D | 1.888 | 1.00 | |
| 152_V | 157_R | 1.886 | 1.00 | |
| 74_A | 189_L | 1.826 | 1.00 | |
| 152_V | 199_L | 1.803 | 1.00 | |
| 28_K | 194_D | 1.794 | 1.00 | |
| 98_V | 209_F | 1.776 | 1.00 | |
| 75_V | 169_I | 1.765 | 1.00 | |
| 69_H | 157_R | 1.686 | 1.00 | |
| 74_A | 187_V | 1.684 | 1.00 | |
| 86_E | 168_K | 1.648 | 1.00 | |
| 53_D | 56_Q | 1.576 | 1.00 | |
| 90_R | 170_V | 1.574 | 1.00 | |
| 145_N | 161_T | 1.571 | 1.00 | |
| 24_S | 35_S | 1.567 | 1.00 | |
| 49_T | 183_K | 1.562 | 1.00 | |
| 80_T | 184_A | 1.562 | 1.00 | |
| 128_C | 189_L | 1.55 | 1.00 | |
| 60_I | 67_V | 1.542 | 1.00 | |
| 22_V | 43_L | 1.521 | 1.00 | |
| 59_A | 126_N | 1.498 | 1.00 | |
| 28_K | 164_D | 1.487 | 1.00 | |
| 102_L | 199_L | 1.485 | 1.00 | |
| 71_V | 148_L | 1.468 | 1.00 | |
| 43_L | 176_M | 1.465 | 1.00 | |
| 149_S | 156_Q | 1.436 | 1.00 | |
| 73_L | 209_F | 1.423 | 1.00 | |
| 52_C | 56_Q | 1.401 | 0.99 | |
| 144_Q | 170_V | 1.341 | 0.99 | |
| 22_V | 172_L | 1.338 | 0.99 | |
| 27_A | 31_K | 1.337 | 0.99 | |
| 99_A | 128_C | 1.33 | 0.99 | |
| 64_F | 67_V | 1.312 | 0.99 | |
| 119_E | 123_A | 1.311 | 0.99 | |
| 45_I | 119_E | 1.299 | 0.99 | |
| 24_S | 33_M | 1.272 | 0.99 | |
| 19_V | 128_C | 1.271 | 0.99 | |
| 64_F | 106_D | 1.254 | 0.99 | |
| 144_Q | 168_K | 1.251 | 0.99 | |
| 145_N | 163_A | 1.248 | 0.99 | |
| 204_E | 215_T | 1.242 | 0.98 | |
| 58_L | 102_L | 1.237 | 0.98 | |
| 57_P | 217_R | 1.236 | 0.98 | |
| 77_I | 173_I | 1.233 | 0.98 | |
| 17_S | 183_K | 1.223 | 0.98 | |
| 97_G | 131_S | 1.212 | 0.98 | |
| 82_R | 125_D | 1.201 | 0.98 | |
| 80_T | 92_A | 1.201 | 0.98 | |
| 82_R | 181_T | 1.196 | 0.98 | |
| 52_C | 126_N | 1.193 | 0.98 | |
| 29_H | 105_R | 1.188 | 0.98 | |
| 79_A | 92_A | 1.181 | 0.98 | |
| 150_L | 207_V | 1.166 | 0.97 | |
| 154_G | 206_T | 1.161 | 0.97 | |
| 142_D | 145_N | 1.152 | 0.97 | |
| 68_H | 105_R | 1.148 | 0.97 | |
| 58_L | 205_L | 1.144 | 0.97 | |
| 26_Y | 190_T | 1.133 | 0.97 | |
| 79_A | 91_K | 1.119 | 0.96 | |
| 144_Q | 165_M | 1.107 | 0.96 | |
| 33_M | 103_T | 1.06 | 0.95 | |
| 96_Y | 136_A | 1.045 | 0.94 | |
| 30_I | 37_V | 1.042 | 0.94 | |
| 60_I | 201_S | 1.039 | 0.94 | |
| 65_G | 106_D | 1.033 | 0.94 | |
| 174_A | 178_K | 1.03 | 0.94 | |
| 100_L | 216_T | 1.019 | 0.93 | |
| 77_I | 182_L | 1.017 | 0.93 | |
| 74_A | 130_L | 1.016 | 0.93 | |
| 97_G | 130_L | 1.015 | 0.93 | |
| 98_V | 207_V | 1.009 | 0.93 | |
| 43_L | 175_Y | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4dbfA | 2 | 0.9772 | 100 | 0.14 | Contact Map | 0.782 |
| 3rr6A | 1 | 0.968 | 100 | 0.15 | Contact Map | 0.781 |
| 3s52A | 4 | 0.9954 | 100 | 0.162 | Contact Map | 0.811 |
| 3r6oA | 1 | 0.9909 | 100 | 0.163 | Contact Map | 0.722 |
| 4maqA | 2 | 0.9954 | 100 | 0.164 | Contact Map | 0.812 |
| 1wzoA | 4 | 0.9817 | 100 | 0.175 | Contact Map | 0.904 |
| 2dfuA | 4 | 0.968 | 100 | 0.179 | Contact Map | 0.886 |
| 1sawA | 2 | 0.9817 | 100 | 0.185 | Contact Map | 0.862 |
| 3l53A | 6 | 0.9909 | 100 | 0.187 | Contact Map | 0.787 |
| 1gttA | 4 | 0.9772 | 100 | 0.189 | Contact Map | 0.883 |
Sequence Conservation (Image Generated using WebLogo v3)