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OPENSEQ.org
YMFN - Uncharacterized protein YmfN
UniProt: P75978 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14252
Length: 455 (401)
Sequences: 726
Seq/Len: 1.81
YMFN
Paralog alert: 0.26 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
165_P 185_L 5.467 1.00
247_A 253_N 3.353 1.00
201_F 206_L 3.133 1.00
239_P 334_S 3.046 1.00
202_K 208_I 2.902 1.00
394_C 423_G 2.887 1.00
374_L 427_L 2.7 1.00
275_R 308_T 2.685 1.00
256_A 426_A 2.593 1.00
253_N 320_I 2.581 1.00
223_Q 392_T 2.539 1.00
222_W 385_H 2.517 1.00
272_V 427_L 2.48 1.00
240_C 259_Y 2.446 1.00
157_D 170_K 2.398 1.00
276_F 423_G 2.312 1.00
239_P 332_P 2.269 1.00
395_I 424_A 2.249 1.00
133_R 155_T 2.223 1.00
335_E 433_R 2.202 0.99
136_V 151_G 2.165 0.99
363_N 366_N 2.091 0.99
252_M 394_C 1.984 0.99
403_I 408_D 1.961 0.98
274_P 388_N 1.873 0.98
88_V 94_H 1.873 0.98
156_V 171_A 1.84 0.97
222_W 395_I 1.788 0.97
302_V 309_V 1.758 0.96
92_H 122_G 1.74 0.96
156_V 167_V 1.728 0.96
321_L 349_D 1.712 0.96
156_V 206_L 1.691 0.95
346_L 350_L 1.691 0.95
91_Y 128_P 1.69 0.95
119_T 129_C 1.687 0.95
174_N 178_S 1.685 0.95
324_A 350_L 1.684 0.95
258_L 430_A 1.675 0.95
224_S 381_G 1.666 0.95
277_W 323_E 1.653 0.94
242_L 257_R 1.649 0.94
160_D 170_K 1.633 0.94
83_P 106_G 1.621 0.94
398_V 424_A 1.613 0.93
135_E 146_N 1.604 0.93
325_K 353_E 1.583 0.92
256_A 274_P 1.58 0.92
398_V 412_P 1.563 0.92
130_Y 209_W 1.551 0.91
425_V 429_M 1.548 0.91
278_V 309_V 1.54 0.91
397_N 414_K 1.537 0.91
135_E 139_M 1.536 0.91
236_E 330_I 1.534 0.91
97_D 101_T 1.533 0.91
79_D 204_K 1.52 0.90
92_H 119_T 1.491 0.89
91_Y 117_A 1.491 0.89
148_E 186_S 1.48 0.89
188_Q 201_F 1.479 0.89
367_M 425_V 1.478 0.89
361_I 366_N 1.444 0.87
240_C 257_R 1.442 0.87
367_M 429_M 1.435 0.87
321_L 346_L 1.43 0.86
336_S 350_L 1.426 0.86
87_V 118_I 1.42 0.86
255_M 277_W 1.419 0.86
403_I 407_D 1.41 0.85
336_S 363_N 1.41 0.85
243_A 426_A 1.409 0.85
94_H 129_C 1.408 0.85
291_D 294_T 1.394 0.84
124_N 130_Y 1.377 0.83
241_I 324_A 1.375 0.83
86_A 103_M 1.369 0.83
300_K 304_M 1.366 0.83
244_F 255_M 1.362 0.82
242_L 324_A 1.356 0.82
79_D 102_T 1.352 0.82
138_E 143_S 1.349 0.82
120_T 207_N 1.348 0.82
82_S 109_A 1.348 0.82
247_A 315_V 1.345 0.81
121_A 209_W 1.339 0.81
105_T 200_V 1.326 0.80
340_P 361_I 1.318 0.80
338_I 357_P 1.314 0.79
217_F 395_I 1.303 0.78
161_D 206_L 1.299 0.78
176_G 277_W 1.299 0.78
276_F 394_C 1.287 0.77
254_S 276_F 1.273 0.76
82_S 110_R 1.24 0.73
246_L 317_Y 1.239 0.73
109_A 113_P 1.239 0.73
88_V 117_A 1.238 0.73
46_I 49_Q 1.237 0.73
254_S 423_G 1.227 0.72
73_K 81_S 1.226 0.72
414_K 422_D 1.212 0.71
255_M 323_E 1.208 0.71
136_V 139_M 1.203 0.70
222_W 392_T 1.201 0.70
134_R 138_E 1.196 0.70
146_N 190_R 1.195 0.69
138_E 144_V 1.193 0.69
255_M 324_A 1.189 0.69
139_M 142_G 1.189 0.69
252_M 420_K 1.184 0.68
93_E 102_T 1.182 0.68
394_C 424_A 1.179 0.68
337_P 433_R 1.179 0.68
129_C 209_W 1.178 0.68
258_L 427_L 1.175 0.68
97_D 131_D 1.174 0.68
79_D 120_T 1.172 0.67
253_N 317_Y 1.167 0.67
323_E 327_A 1.166 0.67
35_D 45_T 1.166 0.67
251_D 422_D 1.159 0.66
258_L 431_V 1.156 0.66
172_N 205_H 1.155 0.66
130_Y 134_R 1.155 0.66
190_R 197_L 1.15 0.65
132_K 149_L 1.14 0.64
125_I 130_Y 1.14 0.64
164_D 167_V 1.133 0.63
299_Q 302_V 1.133 0.63
104_L 187_Q 1.128 0.63
271_S 384_H 1.126 0.63
243_A 430_A 1.12 0.62
188_Q 206_L 1.12 0.62
368_S 372_K 1.117 0.62
84_H 110_R 1.115 0.62
412_P 428_I 1.113 0.61
74_A 78_G 1.113 0.61
78_G 102_T 1.103 0.60
235_F 273_A 1.093 0.59
168_L 185_L 1.087 0.59
250_L 420_K 1.084 0.58
225_C 378_I 1.082 0.58
303_E 308_T 1.08 0.58
36_E 40_W 1.079 0.58
77_Q 81_S 1.076 0.58
91_Y 94_H 1.074 0.57
133_R 137_I 1.072 0.57
165_P 168_L 1.07 0.57
242_L 333_V 1.069 0.57
198_A 202_K 1.069 0.57
265_G 320_I 1.061 0.56
301_W 307_L 1.061 0.56
37_G 71_T 1.061 0.56
124_N 127_G 1.051 0.55
34_N 38_V 1.047 0.54
275_R 323_E 1.047 0.54
79_D 203_T 1.042 0.54
107_M 115_M 1.042 0.54
68_G 171_A 1.041 0.54
232_L 331_S 1.04 0.54
377_A 431_V 1.038 0.53
108_G 205_H 1.033 0.53
274_P 391_M 1.032 0.53
216_Y 375_E 1.031 0.53
297_R 301_W 1.025 0.52
374_L 378_I 1.025 0.52
186_S 189_Q 1.024 0.52
315_V 320_I 1.022 0.52
73_K 146_N 1.015 0.51
333_V 391_M 1.005 0.50
37_G 44_E 1.003 0.50
231_T 234_Q 1.002 0.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3cpeA10.81000.723Contact Map0.522
4idhA10.80221000.754Contact Map0.59
2o0jA10.402299.60.855Contact Map0.568
4bijA50.716599.40.876Contact Map0.143
3c6aA10.463798.30.917Contact Map0.58
2wbnA10.44492.80.952Contact Map0.499
3dkpA10.305539.40.97Contact Map0.587
3berA10.296736.40.971Contact Map0.5
2pl3A10.303334.30.971Contact Map0.543
3fe2A20.3055340.971Contact Map0.58
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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