May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
FLGD - Basal-body rod modification protein FlgD
UniProt: P75936 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14268
Length: 231 (204)
Sequences: 593
Seq/Len: 2.91
FLGD
Paralog alert: 0.14 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
168_L 172_S 4.819 1.00
141_D 145_A 4.322 1.00
132_A 135_V 3.628 1.00
53_E 56_E 2.895 1.00
168_L 174_A 2.563 1.00
100_V 202_V 2.543 1.00
140_T 146_V 2.504 1.00
47_D 50_N 2.418 1.00
140_T 182_A 2.251 1.00
70_I 73_L 2.174 1.00
223_T 226_E 2.143 1.00
59_S 64_I 2.009 1.00
148_R 169_T 1.96 1.00
66_T 70_I 1.807 0.99
128_L 132_A 1.786 0.99
138_T 146_V 1.749 0.99
32_Q 68_S 1.742 0.99
167_T 173_T 1.69 0.98
92_A 205_V 1.651 0.98
200_A 216_L 1.61 0.97
166_G 171_G 1.585 0.97
73_L 77_L 1.546 0.96
93_S 230_I 1.522 0.96
137_A 181_V 1.49 0.95
214_L 227_V 1.439 0.94
140_T 180_N 1.388 0.92
148_R 167_T 1.378 0.92
109_A 174_A 1.371 0.92
39_L 58_T 1.354 0.91
210_S 213_T 1.342 0.90
59_S 62_A 1.331 0.90
34_S 58_T 1.328 0.90
59_S 63_Q 1.325 0.90
36_L 40_V 1.304 0.89
49_T 57_L 1.298 0.88
39_L 74_N 1.294 0.88
43_L 57_L 1.293 0.88
147_V 174_A 1.29 0.88
66_T 69_G 1.288 0.88
138_T 184_S 1.282 0.88
148_R 165_D 1.278 0.87
58_T 64_I 1.273 0.87
133_D 187_N 1.259 0.86
42_Q 62_A 1.239 0.85
31_L 34_S 1.239 0.85
96_I 218_T 1.218 0.84
139_I 181_V 1.212 0.83
204_G 215_D 1.207 0.83
149_T 169_T 1.191 0.82
34_S 64_I 1.184 0.81
132_A 185_A 1.166 0.80
155_L 160_H 1.16 0.79
40_V 153_G 1.155 0.79
164_W 171_G 1.154 0.79
40_V 45_N 1.145 0.78
137_A 183_I 1.14 0.78
152_I 155_L 1.137 0.78
58_T 66_T 1.133 0.77
40_V 67_V 1.129 0.77
95_L 100_V 1.126 0.77
57_L 64_I 1.126 0.77
81_S 84_I 1.108 0.75
185_A 194_A 1.108 0.75
92_A 224_L 1.095 0.74
88_Q 91_Q 1.08 0.72
49_T 61_L 1.079 0.72
37_T 44_K 1.075 0.72
52_M 63_Q 1.075 0.72
67_V 103_P 1.071 0.71
128_L 153_G 1.071 0.71
214_L 224_L 1.07 0.71
102_I 222_T 1.069 0.71
61_L 68_S 1.069 0.71
50_N 54_N 1.06 0.70
137_A 152_I 1.06 0.70
69_G 73_L 1.048 0.69
69_G 74_N 1.042 0.68
32_Q 112_G 1.028 0.67
100_V 214_L 1.024 0.66
57_L 61_L 1.024 0.66
207_R 210_S 1.021 0.66
96_I 124_F 1.011 0.65
54_N 69_G 1.011 0.65
34_S 57_L 1.008 0.65
131_A 154_E 1.005 0.64
64_I 96_I 1.004 0.64
32_Q 61_L 1.001 0.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3c12A10.59311000.542Contact Map0.655
3osvA40.58441000.556Contact Map0.726
1xf1A20.922199.30.787Contact Map0.608
2c9rA10.333382.80.928Contact Map0.24
1lyqA20.337778.60.931Contact Map0.213
3isyA10.415675.60.933Contact Map0.811
3sd2A10.36856.20.941Contact Map0.636
2d7nA10.38149.70.943Contact Map0.548
3d33A20.428638.30.947Contact Map0.52
3tkvA10.419936.60.948Contact Map0
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.022 seconds.