| UniProt: | P75897 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13858 | ||
| Length: | 230 (215) | ||
| Sequences: | 2656 | ||
| Seq/Len: | 12.35 |
| RUTB
Paralog alert: 0.60 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: PNCA RUTB YCAC YECD |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 145_D | 179_Y | 4.799 | 1.00 | |
| 145_D | 149_R | 3.259 | 1.00 | |
| 137_S | 173_D | 2.97 | 1.00 | |
| 71_Q | 132_P | 2.821 | 1.00 | |
| 28_A | 115_D | 2.721 | 1.00 | |
| 56_A | 184_L | 2.629 | 1.00 | |
| 184_L | 217_F | 2.602 | 1.00 | |
| 158_F | 171_L | 2.449 | 1.00 | |
| 60_A | 65_M | 2.386 | 1.00 | |
| 25_M | 53_I | 2.344 | 1.00 | |
| 204_I | 209_G | 2.289 | 1.00 | |
| 53_I | 159_T | 2.245 | 1.00 | |
| 145_D | 177_L | 2.219 | 1.00 | |
| 55_T | 215_E | 2.215 | 1.00 | |
| 155_H | 182_V | 2.206 | 1.00 | |
| 213_D | 216_T | 2.196 | 1.00 | |
| 59_A | 63_A | 2.19 | 1.00 | |
| 155_H | 180_F | 2.115 | 1.00 | |
| 193_P | 198_K | 2.078 | 1.00 | |
| 185_E | 211_V | 2.075 | 1.00 | |
| 163_T | 197_Q | 2.044 | 1.00 | |
| 19_A | 153_I | 2.027 | 1.00 | |
| 168_E | 172_R | 2.024 | 1.00 | |
| 143_P | 147_I | 2.018 | 1.00 | |
| 138_G | 170_T | 2.009 | 1.00 | |
| 158_F | 170_T | 1.979 | 1.00 | |
| 83_G | 107_K | 1.959 | 1.00 | |
| 60_A | 157_V | 1.929 | 1.00 | |
| 22_V | 57_V | 1.911 | 1.00 | |
| 186_D | 214_V | 1.906 | 1.00 | |
| 27_N | 114_W | 1.853 | 1.00 | |
| 187_A | 214_V | 1.796 | 1.00 | |
| 157_V | 184_L | 1.779 | 1.00 | |
| 61_R | 128_D | 1.769 | 1.00 | |
| 17_Q | 154_R | 1.75 | 1.00 | |
| 45_T | 48_P | 1.743 | 1.00 | |
| 156_L | 174_G | 1.741 | 1.00 | |
| 30_A | 119_V | 1.663 | 1.00 | |
| 185_E | 213_D | 1.662 | 1.00 | |
| 52_N | 55_T | 1.654 | 1.00 | |
| 163_T | 188_T | 1.65 | 1.00 | |
| 135_R | 178_E | 1.633 | 1.00 | |
| 185_E | 201_L | 1.619 | 1.00 | |
| 59_A | 218_C | 1.61 | 1.00 | |
| 190_Q | 197_Q | 1.596 | 1.00 | |
| 174_G | 181_G | 1.595 | 1.00 | |
| 21_I | 144_L | 1.586 | 1.00 | |
| 21_I | 158_F | 1.569 | 1.00 | |
| 18_S | 155_H | 1.533 | 1.00 | |
| 18_S | 157_V | 1.527 | 1.00 | |
| 198_K | 202_F | 1.526 | 1.00 | |
| 52_N | 187_A | 1.506 | 1.00 | |
| 23_V | 158_F | 1.468 | 1.00 | |
| 27_N | 120_D | 1.446 | 1.00 | |
| 163_T | 201_L | 1.433 | 1.00 | |
| 24_D | 133_K | 1.431 | 1.00 | |
| 194_K | 198_K | 1.426 | 1.00 | |
| 52_N | 214_V | 1.4 | 0.99 | |
| 22_V | 159_T | 1.393 | 0.99 | |
| 23_V | 166_C | 1.391 | 0.99 | |
| 66_L | 151_R | 1.35 | 0.99 | |
| 54_Q | 58_T | 1.346 | 0.99 | |
| 56_A | 217_F | 1.345 | 0.99 | |
| 167_V | 183_V | 1.307 | 0.99 | |
| 58_T | 62_A | 1.304 | 0.99 | |
| 19_A | 68_I | 1.291 | 0.99 | |
| 68_I | 147_I | 1.27 | 0.99 | |
| 168_E | 200_A | 1.265 | 0.99 | |
| 129_I | 147_I | 1.245 | 0.98 | |
| 188_T | 197_Q | 1.244 | 0.98 | |
| 22_V | 53_I | 1.243 | 0.98 | |
| 114_W | 117_Q | 1.231 | 0.98 | |
| 20_L | 60_A | 1.225 | 0.98 | |
| 168_E | 203_N | 1.213 | 0.98 | |
| 149_R | 179_Y | 1.211 | 0.98 | |
| 184_L | 212_S | 1.21 | 0.98 | |
| 183_V | 201_L | 1.206 | 0.98 | |
| 183_V | 188_T | 1.203 | 0.98 | |
| 164_N | 190_Q | 1.178 | 0.98 | |
| 54_Q | 124_P | 1.178 | 0.98 | |
| 125_Q | 128_D | 1.178 | 0.98 | |
| 29_Y | 166_C | 1.172 | 0.98 | |
| 154_R | 180_F | 1.16 | 0.97 | |
| 28_A | 34_G | 1.16 | 0.97 | |
| 124_P | 130_V | 1.144 | 0.97 | |
| 54_Q | 121_E | 1.14 | 0.97 | |
| 25_M | 122_L | 1.137 | 0.97 | |
| 214_V | 218_C | 1.131 | 0.97 | |
| 143_P | 146_S | 1.126 | 0.97 | |
| 49_V | 53_I | 1.116 | 0.96 | |
| 173_D | 177_L | 1.115 | 0.96 | |
| 131_L | 147_I | 1.112 | 0.96 | |
| 169_S | 172_R | 1.11 | 0.96 | |
| 27_N | 31_T | 1.083 | 0.96 | |
| 146_S | 150_S | 1.078 | 0.95 | |
| 171_L | 183_V | 1.077 | 0.95 | |
| 184_L | 187_A | 1.075 | 0.95 | |
| 57_V | 69_W | 1.073 | 0.95 | |
| 140_F | 177_L | 1.066 | 0.95 | |
| 69_W | 128_D | 1.058 | 0.95 | |
| 117_Q | 123_V | 1.058 | 0.95 | |
| 69_W | 118_L | 1.043 | 0.94 | |
| 73_G | 111_K | 1.031 | 0.94 | |
| 215_E | 219_D | 1.018 | 0.93 | |
| 27_N | 117_Q | 1.01 | 0.93 | |
| 139_F | 174_G | 1.009 | 0.93 | |
| 70_F | 138_G | 1.006 | 0.93 | |
| 192_G | 195_F | 1.003 | 0.93 | |
| 216_T | 219_D | 1.002 | 0.92 | |
| 118_L | 130_V | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3kl2A | 12 | 0.9391 | 100 | 0.249 | Contact Map | 0.825 |
| 2fq1A | 2 | 0.8957 | 100 | 0.257 | Contact Map | 0.811 |
| 3irvA | 1 | 0.913 | 100 | 0.265 | Contact Map | 0.834 |
| 3hb7A | 8 | 0.8348 | 100 | 0.266 | Contact Map | 0.877 |
| 1nbaA | 4 | 0.9217 | 100 | 0.276 | Contact Map | 0.871 |
| 1nf9A | 1 | 0.8391 | 100 | 0.277 | Contact Map | 0.789 |
| 3hu5A | 2 | 0.8783 | 100 | 0.277 | Contact Map | 0.789 |
| 3r2jA | 4 | 0.8652 | 100 | 0.283 | Contact Map | 0.735 |
| 3tg2A | 1 | 0.8826 | 100 | 0.292 | Contact Map | 0.768 |
| 3ot4A | 8 | 0.9 | 100 | 0.292 | Contact Map | 0.843 |
Sequence Conservation (Image Generated using WebLogo v3)