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OPENSEQ.org
YBGK - Uncharacterized protein YbgK
UniProt: P75745 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13307
Length: 310 (307)
Sequences: 1300
Seq/Len: 4.23
YBGK
Paralog alert: 0.16 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
82_D 98_Q 5.71 1.00
37_L 52_A 4.753 1.00
40_A 114_A 4.747 1.00
175_R 265_D 4.093 1.00
72_L 79_A 3.752 1.00
51_P 128_C 3.736 1.00
70_F 94_M 3.573 1.00
11_T 53_L 3.415 1.00
3_K 63_E 3.172 1.00
3_K 65_E 2.987 1.00
13_V 119_I 2.885 1.00
67_D 95_K 2.823 1.00
95_K 98_Q 2.785 1.00
4_I 62_V 2.694 1.00
55_I 113_L 2.657 1.00
176_A 234_V 2.55 1.00
70_F 92_L 2.496 1.00
38_R 48_A 2.489 1.00
63_E 99_R 2.412 1.00
81_L 94_M 2.294 1.00
115_V 119_I 2.179 1.00
80_R 101_T 2.128 1.00
175_R 262_I 2.122 1.00
40_A 44_V 2.038 1.00
64_F 68_G 1.926 1.00
56_T 110_R 1.915 1.00
234_V 244_V 1.894 1.00
32_L 246_M 1.88 1.00
262_I 283_C 1.855 1.00
67_D 96_A 1.846 1.00
44_V 114_A 1.839 1.00
262_I 265_D 1.833 1.00
261_I 265_D 1.823 1.00
31_A 37_L 1.8 1.00
64_F 94_M 1.734 0.99
27_S 131_D 1.729 0.99
123_P 128_C 1.721 0.99
61_T 101_T 1.693 0.99
284_S 287_E 1.675 0.99
77_C 111_S 1.672 0.99
231_P 249_A 1.649 0.99
181_E 257_R 1.603 0.99
176_A 259_A 1.599 0.99
55_I 111_S 1.598 0.99
193_F 234_V 1.563 0.98
81_L 86_V 1.56 0.98
138_G 141_G 1.558 0.98
216_L 236_V 1.55 0.98
38_R 296_Q 1.549 0.98
197_P 279_H 1.538 0.98
7_A 146_D 1.536 0.98
22_R 249_A 1.536 0.98
31_A 52_A 1.534 0.98
261_I 269_L 1.532 0.98
199_Q 277_P 1.524 0.98
142_R 148_D 1.504 0.98
86_V 92_L 1.504 0.98
3_K 149_R 1.493 0.98
181_E 227_H 1.49 0.98
62_V 100_L 1.479 0.98
194_W 282_Q 1.472 0.97
78_E 103_K 1.47 0.97
66_T 96_A 1.462 0.97
77_C 102_L 1.451 0.97
5_I 63_E 1.445 0.97
44_V 71_A 1.445 0.97
185_F 236_V 1.444 0.97
273_P 276_Q 1.43 0.97
40_A 73_T 1.428 0.97
2_L 62_V 1.424 0.97
71_A 114_A 1.422 0.97
71_A 91_R 1.41 0.97
79_A 102_L 1.409 0.96
64_F 100_L 1.373 0.96
199_Q 212_Q 1.369 0.96
76_G 106_Q 1.365 0.96
207_M 250_Q 1.358 0.95
16_G 38_R 1.344 0.95
2_L 64_F 1.343 0.95
187_R 191_D 1.339 0.95
11_T 60_L 1.326 0.95
119_I 128_C 1.322 0.94
4_I 53_L 1.321 0.94
234_V 259_A 1.319 0.94
197_P 277_P 1.31 0.94
189_S 216_L 1.306 0.94
212_Q 241_Q 1.302 0.94
201_S 212_Q 1.298 0.94
52_A 114_A 1.297 0.94
193_F 280_F 1.296 0.94
227_H 257_R 1.254 0.92
34_M 267_Y 1.249 0.92
209_Y 246_M 1.248 0.92
226_S 229_L 1.246 0.92
10_Y 132_L 1.237 0.91
61_T 99_R 1.235 0.91
5_I 61_T 1.231 0.91
131_D 134_V 1.228 0.91
50_A 128_C 1.228 0.91
175_R 283_C 1.222 0.91
44_V 69_W 1.222 0.91
198_W 243_I 1.22 0.91
53_L 60_L 1.216 0.91
46_N 118_G 1.181 0.89
55_I 60_L 1.18 0.89
5_I 99_R 1.169 0.88
173_R 281_V 1.156 0.87
244_V 269_L 1.152 0.87
185_F 258_I 1.137 0.86
26_I 125_M 1.125 0.85
77_C 105_P 1.122 0.85
178_P 194_W 1.113 0.85
55_I 77_C 1.108 0.84
6_R 61_T 1.105 0.84
223_E 256_P 1.105 0.84
130_T 138_G 1.104 0.84
8_G 11_T 1.099 0.84
134_V 252_T 1.095 0.83
40_A 71_A 1.095 0.83
220_T 234_V 1.092 0.83
70_F 81_L 1.075 0.82
62_V 113_L 1.075 0.82
13_V 51_P 1.06 0.80
16_G 49_N 1.059 0.80
81_L 100_L 1.056 0.80
32_L 209_Y 1.054 0.80
246_M 270_A 1.05 0.79
235_Q 255_Y 1.049 0.79
218_R 222_R 1.048 0.79
44_V 116_A 1.043 0.79
178_P 190_Q 1.04 0.79
69_W 93_P 1.04 0.79
13_V 128_C 1.037 0.78
272_I 278_I 1.019 0.77
218_R 223_E 1.018 0.76
133_K 205_N 1.008 0.76
43_L 71_A 1.007 0.75
7_A 144_L 1.002 0.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3mmlA40.97421000.058Contact Map0.779
3va7A10.99681000.096Contact Map0.819
3oepA10.87741000.106Contact Map0.82
2zp2A20.419480.90.956Contact Map0.741
2phcB10.5871390.967Contact Map0.736
1f0zA10.183935.90.967Contact Map0.372
2pieA10.380623.70.97Contact Map0.625
2cu3A20.177419.20.971Contact Map0.726
1vykA10.225813.80.973Contact Map0.854
2brfA10.287113.20.973Contact Map0.69
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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