| UniProt: | P75682 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13344 | ||
| Length: | 302 (295) | ||
| Sequences: | 4538 | ||
| Seq/Len: | 15.38 |
| YAGE
Paralog alert: 0.62 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: DAPA NANA YAGE YJHH |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 234_D | 237_K | 4.512 | 1.00 | |
| 19_T | 23_Q | 3.519 | 1.00 | |
| 34_D | 71_H | 3.346 | 1.00 | |
| 121_I | 155_T | 3.136 | 1.00 | |
| 98_Q | 132_T | 3.025 | 1.00 | |
| 82_T | 94_S | 2.897 | 1.00 | |
| 26_K | 63_A | 2.892 | 1.00 | |
| 268_L | 293_K | 2.75 | 1.00 | |
| 30_A | 71_H | 2.68 | 1.00 | |
| 229_A | 237_K | 2.675 | 1.00 | |
| 26_K | 67_F | 2.671 | 1.00 | |
| 203_T | 208_G | 2.598 | 1.00 | |
| 30_A | 67_F | 2.464 | 1.00 | |
| 34_D | 75_R | 2.342 | 1.00 | |
| 237_K | 240_G | 2.284 | 1.00 | |
| 94_S | 105_I | 2.258 | 1.00 | |
| 62_K | 96_H | 2.19 | 1.00 | |
| 229_A | 234_D | 2.18 | 1.00 | |
| 117_E | 152_L | 2.171 | 1.00 | |
| 30_A | 70_D | 2.136 | 1.00 | |
| 118_A | 122_R | 2.112 | 1.00 | |
| 228_K | 232_D | 2.087 | 1.00 | |
| 42_D | 228_K | 2.081 | 1.00 | |
| 11_I | 43_G | 2.079 | 1.00 | |
| 12_P | 216_G | 2.076 | 1.00 | |
| 147_D | 175_H | 2.061 | 1.00 | |
| 34_D | 38_K | 2.006 | 1.00 | |
| 63_A | 66_R | 1.985 | 1.00 | |
| 66_R | 70_D | 1.961 | 1.00 | |
| 33_I | 68_A | 1.947 | 1.00 | |
| 129_D | 160_R | 1.945 | 1.00 | |
| 118_A | 155_T | 1.938 | 1.00 | |
| 121_I | 125_E | 1.937 | 1.00 | |
| 125_E | 129_D | 1.927 | 1.00 | |
| 35_D | 39_A | 1.903 | 1.00 | |
| 204_L | 230_W | 1.897 | 1.00 | |
| 87_A | 123_Y | 1.894 | 1.00 | |
| 153_V | 166_I | 1.889 | 1.00 | |
| 136_M | 165_G | 1.854 | 1.00 | |
| 125_E | 160_R | 1.838 | 1.00 | |
| 69_I | 78_V | 1.753 | 1.00 | |
| 136_M | 212_I | 1.753 | 1.00 | |
| 128_A | 160_R | 1.75 | 1.00 | |
| 25_D | 28_G | 1.74 | 1.00 | |
| 63_A | 67_F | 1.729 | 1.00 | |
| 240_G | 244_T | 1.723 | 1.00 | |
| 60_E | 278_L | 1.715 | 1.00 | |
| 39_A | 221_Q | 1.711 | 1.00 | |
| 224_V | 228_K | 1.7 | 1.00 | |
| 293_K | 297_Q | 1.698 | 1.00 | |
| 222_V | 244_T | 1.691 | 1.00 | |
| 290_A | 293_K | 1.675 | 1.00 | |
| 58_A | 89_E | 1.669 | 1.00 | |
| 28_G | 31_A | 1.664 | 1.00 | |
| 91_I | 126_Q | 1.662 | 1.00 | |
| 149_T | 152_L | 1.641 | 1.00 | |
| 107_V | 127_V | 1.614 | 1.00 | |
| 29_T | 64_I | 1.594 | 1.00 | |
| 29_T | 68_A | 1.59 | 1.00 | |
| 122_R | 125_E | 1.584 | 1.00 | |
| 117_E | 149_T | 1.552 | 1.00 | |
| 156_L | 163_I | 1.519 | 1.00 | |
| 264_E | 289_K | 1.518 | 1.00 | |
| 37_I | 75_R | 1.491 | 1.00 | |
| 15_S | 266_I | 1.483 | 1.00 | |
| 65_A | 80_I | 1.48 | 1.00 | |
| 290_A | 294_T | 1.476 | 1.00 | |
| 105_I | 131_V | 1.471 | 1.00 | |
| 90_T | 127_V | 1.456 | 1.00 | |
| 17_I | 29_T | 1.441 | 1.00 | |
| 11_I | 45_F | 1.42 | 1.00 | |
| 95_Q | 99_Q | 1.415 | 1.00 | |
| 94_S | 131_V | 1.409 | 1.00 | |
| 122_R | 126_Q | 1.408 | 1.00 | |
| 225_N | 229_A | 1.402 | 0.99 | |
| 98_Q | 131_V | 1.399 | 0.99 | |
| 33_I | 72_V | 1.373 | 0.99 | |
| 180_I | 192_V | 1.371 | 0.99 | |
| 267_V | 275_T | 1.364 | 0.99 | |
| 46_F | 68_A | 1.357 | 0.99 | |
| 67_F | 71_H | 1.355 | 0.99 | |
| 67_F | 70_D | 1.354 | 0.99 | |
| 37_I | 76_V | 1.349 | 0.99 | |
| 33_I | 71_H | 1.332 | 0.99 | |
| 286_E | 289_K | 1.316 | 0.99 | |
| 225_N | 228_K | 1.31 | 0.99 | |
| 84_G | 90_T | 1.305 | 0.99 | |
| 62_K | 92_E | 1.293 | 0.99 | |
| 42_D | 224_V | 1.281 | 0.99 | |
| 10_I | 41_V | 1.276 | 0.99 | |
| 52_E | 263_K | 1.26 | 0.99 | |
| 79_L | 136_M | 1.252 | 0.99 | |
| 230_W | 235_V | 1.243 | 0.98 | |
| 126_Q | 279_P | 1.212 | 0.98 | |
| 58_A | 96_H | 1.209 | 0.98 | |
| 267_V | 272_P | 1.207 | 0.98 | |
| 59_E | 63_A | 1.206 | 0.98 | |
| 201_F | 238_A | 1.204 | 0.98 | |
| 236_A | 239_A | 1.201 | 0.98 | |
| 72_V | 78_V | 1.197 | 0.98 | |
| 79_L | 104_G | 1.194 | 0.98 | |
| 286_E | 290_A | 1.192 | 0.98 | |
| 264_E | 268_L | 1.19 | 0.98 | |
| 285_D | 288_R | 1.178 | 0.98 | |
| 235_V | 239_A | 1.176 | 0.98 | |
| 28_G | 274_S | 1.173 | 0.98 | |
| 23_Q | 88_R | 1.168 | 0.97 | |
| 62_K | 66_R | 1.158 | 0.97 | |
| 294_T | 298_Q | 1.154 | 0.97 | |
| 8_T | 231_R | 1.149 | 0.97 | |
| 45_F | 106_V | 1.134 | 0.97 | |
| 58_A | 92_E | 1.133 | 0.97 | |
| 30_A | 34_D | 1.13 | 0.97 | |
| 91_I | 95_Q | 1.13 | 0.97 | |
| 155_T | 158_D | 1.128 | 0.97 | |
| 69_I | 103_D | 1.127 | 0.97 | |
| 225_N | 237_K | 1.121 | 0.97 | |
| 65_A | 97_A | 1.113 | 0.96 | |
| 96_H | 99_Q | 1.108 | 0.96 | |
| 35_D | 271_R | 1.106 | 0.96 | |
| 82_T | 97_A | 1.104 | 0.96 | |
| 105_I | 135_V | 1.094 | 0.96 | |
| 154_K | 182_T | 1.086 | 0.96 | |
| 86_N | 89_E | 1.084 | 0.96 | |
| 272_P | 275_T | 1.082 | 0.96 | |
| 62_K | 99_Q | 1.08 | 0.95 | |
| 291_Q | 294_T | 1.073 | 0.95 | |
| 284_L | 292_L | 1.072 | 0.95 | |
| 109_N | 148_L | 1.066 | 0.95 | |
| 126_Q | 130_S | 1.056 | 0.95 | |
| 98_Q | 133_L | 1.051 | 0.94 | |
| 137_L | 153_V | 1.049 | 0.94 | |
| 47_L | 64_I | 1.045 | 0.94 | |
| 12_P | 41_V | 1.043 | 0.94 | |
| 58_A | 93_L | 1.041 | 0.94 | |
| 128_A | 163_I | 1.035 | 0.94 | |
| 32_L | 266_I | 1.034 | 0.94 | |
| 176_L | 203_T | 1.032 | 0.94 | |
| 10_I | 227_L | 1.032 | 0.94 | |
| 118_A | 121_I | 1.029 | 0.94 | |
| 264_E | 293_K | 1.025 | 0.93 | |
| 82_T | 105_I | 1.023 | 0.93 | |
| 26_K | 30_A | 1.022 | 0.93 | |
| 105_I | 133_L | 1.019 | 0.93 | |
| 14_V | 44_L | 1.016 | 0.93 | |
| 221_Q | 225_N | 1.007 | 0.93 | |
| 59_E | 92_E | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2v9dA | 4 | 1 | 100 | 0.031 | Contact Map | 0.769 |
| 3si9A | 4 | 0.9834 | 100 | 0.041 | Contact Map | 0.824 |
| 3na8A | 4 | 0.9801 | 100 | 0.041 | Contact Map | 0.789 |
| 3qzeA | 4 | 0.9801 | 100 | 0.043 | Contact Map | 0.83 |
| 3fluA | 4 | 0.9801 | 100 | 0.045 | Contact Map | 0.838 |
| 3cprA | 2 | 0.9735 | 100 | 0.046 | Contact Map | 0.726 |
| 4fhaA | 2 | 0.9768 | 100 | 0.047 | Contact Map | 0.755 |
| 3l21A | 6 | 0.9735 | 100 | 0.047 | Contact Map | 0.79 |
| 2ojpA | 2 | 0.9636 | 100 | 0.049 | Contact Map | 0.779 |
| 3vflA | 2 | 0.9768 | 100 | 0.049 | Contact Map | 0.757 |
Sequence Conservation (Image Generated using WebLogo v3)