| UniProt: | P75680 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | |||
| Length: | 141 (133) | ||
| Sequences: | 3161 | ||
| Seq/Len: | 23.77 |
| INSO1
Paralog alert: 0.67 [within 20: 0.16] - ratio of genomes with paralogs Cluster includes: INSD1 INSD2 INSD3 INSD4 INSD5 INSD6 INSD8 INSF1 INSF2 INSF3 INSF4 INSF5 INSK INSO1 INSO2 YAGA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 33_R | 75_L | 3.207 | 1.00 | |
| 111_N | 114_W | 3.112 | 1.00 | |
| 36_V | 52_I | 3.022 | 1.00 | |
| 35_Q | 59_R | 2.877 | 1.00 | |
| 109_E | 112_Q | 2.783 | 1.00 | |
| 11_H | 14_S | 2.752 | 1.00 | |
| 39_L | 52_I | 2.432 | 1.00 | |
| 107_V | 113_V | 2.426 | 1.00 | |
| 29_R | 67_L | 2.249 | 1.00 | |
| 64_G | 67_L | 2.193 | 1.00 | |
| 39_L | 55_M | 2.115 | 1.00 | |
| 49_A | 69_G | 2.086 | 1.00 | |
| 53_A | 57_T | 2.081 | 1.00 | |
| 101_L | 113_V | 2.069 | 1.00 | |
| 35_Q | 38_E | 2.044 | 1.00 | |
| 63_M | 68_A | 1.953 | 1.00 | |
| 33_R | 74_E | 1.947 | 1.00 | |
| 40_H | 77_L | 1.914 | 1.00 | |
| 120_Y | 127_G | 1.911 | 1.00 | |
| 49_A | 65_R | 1.886 | 1.00 | |
| 47_A | 51_S | 1.885 | 1.00 | |
| 33_R | 71_L | 1.858 | 1.00 | |
| 35_Q | 61_Y | 1.805 | 1.00 | |
| 71_L | 75_L | 1.672 | 1.00 | |
| 67_L | 70_R | 1.631 | 1.00 | |
| 32_L | 63_M | 1.598 | 1.00 | |
| 108_T | 112_Q | 1.565 | 1.00 | |
| 55_M | 58_Q | 1.523 | 1.00 | |
| 104_Q | 113_V | 1.509 | 1.00 | |
| 87_Y | 90_G | 1.456 | 1.00 | |
| 57_T | 62_Q | 1.414 | 1.00 | |
| 123_P | 126_Q | 1.374 | 0.99 | |
| 29_R | 70_R | 1.368 | 0.99 | |
| 91_G | 94_H | 1.367 | 0.99 | |
| 69_G | 73_K | 1.361 | 0.99 | |
| 55_M | 59_R | 1.343 | 0.99 | |
| 53_A | 68_A | 1.315 | 0.99 | |
| 28_R | 67_L | 1.293 | 0.99 | |
| 40_H | 45_G | 1.268 | 0.99 | |
| 38_E | 42_I | 1.251 | 0.99 | |
| 43_S | 46_S | 1.249 | 0.99 | |
| 13_S | 16_K | 1.233 | 0.98 | |
| 17_Y | 21_R | 1.205 | 0.98 | |
| 53_A | 65_R | 1.193 | 0.98 | |
| 28_R | 31_V | 1.179 | 0.98 | |
| 86_R | 89_R | 1.135 | 0.97 | |
| 10_V | 14_S | 1.127 | 0.97 | |
| 116_G | 131_C | 1.103 | 0.96 | |
| 52_I | 72_M | 1.082 | 0.96 | |
| 56_A | 68_A | 1.068 | 0.95 | |
| 37_L | 75_L | 1.066 | 0.95 | |
| 51_S | 55_M | 1.063 | 0.95 | |
| 92_H | 95_V | 1.06 | 0.95 | |
| 66_W | 69_G | 1.051 | 0.94 | |
| 50_R | 69_G | 1.027 | 0.94 | |
| 89_R | 92_H | 1.025 | 0.93 | |
| 29_R | 32_L | 1.01 | 0.93 | |
| 65_R | 69_G | 1.007 | 0.93 | |
| 121_S | 130_G | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3hotA | 2 | 0.9574 | 99.6 | 0.599 | Contact Map | 0.744 |
| 4fcyA | 2 | 0.9716 | 99.5 | 0.607 | Contact Map | 0.526 |
| 3oymA | 2 | 0.9149 | 98.4 | 0.758 | Contact Map | 0.516 |
| 1k78A | 3 | 0.5745 | 98.1 | 0.775 | Contact Map | 0.863 |
| 1pdnC | 1 | 0.5319 | 97.9 | 0.783 | Contact Map | 0.737 |
| 2k27A | 1 | 0.6738 | 97.6 | 0.797 | Contact Map | 0.61 |
| 2ahqA | 1 | 0.5248 | 97.3 | 0.811 | Contact Map | 0.666 |
| 3av9A | 2 | 0.3901 | 97.1 | 0.815 | Contact Map | 0.233 |
| 1u78A | 1 | 0.7589 | 96.1 | 0.835 | Contact Map | 0.697 |
| 4fw2A | 2 | 0.6241 | 95.6 | 0.842 | Contact Map | 0.712 |
Sequence Conservation (Image Generated using WebLogo v3)