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ZNTB - Zinc transport protein ZntB
UniProt: P64423 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13356
Length: 327 (313)
Sequences: 2375
Seq/Len: 7.59
ZNTB
Paralog alert: 0.60 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: CORA ZNTB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
292_G 298_G 6.635 1.00
296_G 303_F 3.898 1.00
112_D 115_L 3.24 1.00
307_C 311_V 3.01 1.00
294_I 297_G 2.509 1.00
291_L 297_G 2.464 1.00
42_W 118_S 2.436 1.00
109_V 116_I 2.307 1.00
294_I 303_F 2.306 1.00
66_V 110_Y 2.287 1.00
301_F 305_I 2.22 1.00
90_L 151_C 2.15 1.00
44_H 120_R 2.056 1.00
291_L 294_I 2.025 1.00
49_H 52_S 2.018 1.00
57_A 67_R 2.017 1.00
301_F 304_S 2.017 1.00
302_G 306_F 2 1.00
304_S 308_I 1.917 1.00
54_Q 58_T 1.897 1.00
299_W 302_G 1.877 1.00
277_F 282_F 1.841 1.00
45_L 56_L 1.817 1.00
299_W 305_I 1.808 1.00
264_A 267_T 1.795 1.00
283_L 306_F 1.762 1.00
297_G 303_F 1.759 1.00
293_G 300_Q 1.741 1.00
127_L 150_V 1.735 1.00
282_F 286_L 1.696 1.00
66_V 85_G 1.693 1.00
286_L 307_C 1.692 1.00
78_R 232_D 1.661 1.00
287_F 296_G 1.649 1.00
291_L 303_F 1.633 1.00
277_F 280_S 1.604 1.00
305_I 309_L 1.599 1.00
156_D 233_R 1.594 1.00
152_D 156_D 1.587 1.00
296_G 304_S 1.583 1.00
155_T 230_I 1.567 1.00
152_D 233_R 1.563 1.00
287_F 303_F 1.563 1.00
303_F 307_C 1.551 1.00
287_F 294_I 1.547 1.00
300_Q 304_S 1.544 1.00
48_V 52_S 1.53 1.00
107_M 154_L 1.507 0.99
69_A 78_R 1.496 0.99
315_G 319_L 1.492 0.99
175_N 186_F 1.492 0.99
312_V 316_G 1.489 0.99
306_F 310_L 1.484 0.99
290_N 295_P 1.48 0.99
169_I 248_T 1.477 0.99
299_W 303_F 1.467 0.99
66_V 82_L 1.431 0.99
173_E 192_K 1.404 0.99
142_D 145_G 1.391 0.99
168_K 186_F 1.39 0.99
198_R 242_D 1.384 0.99
130_V 149_D 1.382 0.99
287_F 297_G 1.322 0.98
21_D 24_G 1.322 0.98
60_P 117_V 1.319 0.98
109_V 118_S 1.311 0.98
311_V 315_G 1.281 0.98
131_V 135_E 1.276 0.98
286_L 310_L 1.271 0.98
291_L 296_G 1.271 0.98
75_T 89_T 1.269 0.98
318_A 322_H 1.265 0.98
266_R 271_S 1.26 0.97
304_S 307_C 1.257 0.97
291_L 306_F 1.246 0.97
143_C 146_W 1.237 0.97
70_L 110_Y 1.237 0.97
75_T 106_A 1.214 0.97
65_N 68_D 1.208 0.97
70_L 108_R 1.206 0.97
62_L 110_Y 1.205 0.96
80_S 228_Q 1.203 0.96
318_A 327_L 1.199 0.96
19_M 29_L 1.196 0.96
283_L 287_F 1.193 0.96
319_L 323_R 1.192 0.96
272_L 279_P 1.191 0.96
307_C 310_L 1.191 0.96
87_L 110_Y 1.185 0.96
111_M 147_L 1.182 0.96
73_E 121_Q 1.175 0.96
69_A 229_D 1.173 0.96
279_P 282_F 1.167 0.96
30_E 33_D 1.167 0.96
296_G 301_F 1.162 0.95
286_L 289_V 1.16 0.95
68_D 156_D 1.158 0.95
310_L 314_I 1.157 0.95
93_I 197_M 1.157 0.95
296_G 299_W 1.15 0.95
63_P 82_L 1.148 0.95
184_R 255_I 1.145 0.95
268_Y 272_L 1.145 0.95
229_D 232_D 1.141 0.95
22_G 29_L 1.139 0.95
284_T 307_C 1.132 0.95
19_M 27_K 1.131 0.94
50_H 54_Q 1.129 0.94
294_I 304_S 1.129 0.94
191_R 253_D 1.127 0.94
107_M 127_L 1.125 0.94
21_D 26_V 1.123 0.94
65_N 80_S 1.119 0.94
24_G 27_K 1.118 0.94
316_G 320_W 1.116 0.94
287_F 299_W 1.112 0.94
92_C 124_V 1.105 0.94
321_L 326_W 1.104 0.94
231_A 235_G 1.104 0.94
294_I 306_F 1.103 0.93
116_I 146_W 1.102 0.93
155_T 233_R 1.093 0.93
273_M 279_P 1.091 0.93
317_V 321_L 1.088 0.93
289_V 294_I 1.086 0.93
294_I 299_W 1.084 0.93
266_R 270_M 1.081 0.93
306_F 309_L 1.079 0.92
21_D 27_K 1.078 0.92
280_S 310_L 1.071 0.92
291_L 302_G 1.065 0.92
259_M 263_L 1.064 0.92
168_K 193_Q 1.061 0.92
27_K 33_D 1.06 0.92
118_S 151_C 1.056 0.91
271_S 278_L 1.055 0.91
23_R 27_K 1.054 0.91
152_D 155_T 1.049 0.91
320_W 324_S 1.046 0.91
205_R 242_D 1.045 0.91
289_V 306_F 1.045 0.91
89_T 108_R 1.042 0.91
76_R 239_D 1.033 0.90
221_D 224_R 1.028 0.90
176_L 251_M 1.024 0.90
65_N 69_A 1.022 0.90
283_L 310_L 1.021 0.89
267_T 274_A 1.013 0.89
302_G 309_L 1.013 0.89
76_R 203_P 1.011 0.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4i0uA1011000.136Contact Map0.789
4ev6A50.99081000.141Contact Map0.69
3nvoA20.79821000.453Contact Map0.68
4egwA20.81041000.457Contact Map0.712
3ck6A50.76451000.466Contact Map0.585
2bbhA10.74011000.536Contact Map0.754
2hn1A10.71871000.553Contact Map0.551
3rkgA10.688179.70.94Contact Map0.387
3t98B10.2844100.965Contact Map0.241
3ci9A20.11629.60.966Contact Map0.829
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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