OPENSEQ.org - RSEC - ECOLI GREMLIN

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RSEC - Sigma-E factor regulatory protein RseC

UniProt:	P46187	Sequence MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFASDVAALCGAILGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ	Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene:	EG13178
Length:	159 (145)
Sequences:	324
Seq/Len:	2.23

RSEC
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Scaled Score	Prob
55_C	59_L	3.452	1.00
68_G	139_L	2.377	1.00
117_G	121_A	2.25	1.00
92_I	96_F	2.223	1.00
6_A	20_C	2.086	0.99
63_Q	141_V	2.029	0.99
3_K	66_E	2.02	0.99
79_L	83_M	2.018	0.99
19_S	50_T	1.836	0.98
4_E	31_S	1.793	0.98
119_L	122_R	1.605	0.95
1_M	71_E	1.546	0.94
109_G	113_G	1.518	0.93
18_V	21_D	1.507	0.93
6_A	18_V	1.507	0.93
10_S	61_P	1.489	0.92
7_T	63_Q	1.474	0.92
103_D	109_G	1.434	0.90
87_V	112_L	1.43	0.90
66_E	140_S	1.401	0.89
103_D	107_L	1.386	0.88
42_K	117_G	1.381	0.88
15_Q	52_V	1.375	0.88
3_K	138_I	1.286	0.82
6_A	37_S	1.274	0.82
87_V	94_S	1.268	0.81
60_V	120_I	1.263	0.81
91_L	99_L	1.262	0.81
24_A	80_L	1.241	0.79
104_V	108_C	1.228	0.78
67_L	140_S	1.223	0.78
134_W	138_I	1.203	0.76
71_E	135_Q	1.198	0.76
72_G	134_W	1.18	0.74
10_S	133_E	1.175	0.74
100_F	104_V	1.161	0.72
75_L	79_L	1.158	0.72
20_C	67_L	1.156	0.72
72_G	76_S	1.15	0.71
1_M	7_T	1.147	0.71
55_C	58_P	1.121	0.69
90_F	110_A	1.119	0.68
20_C	77_S	1.112	0.68
40_L	43_L	1.111	0.68
96_F	100_F	1.111	0.68
34_G	37_S	1.108	0.67
63_Q	121_A	1.105	0.67
39_V	107_L	1.086	0.65
78_A	114_G	1.083	0.65
33_A	65_V	1.083	0.65
17_L	114_G	1.072	0.64
19_S	48_T	1.047	0.61
1_M	4_E	1.028	0.59
130_A	133_E	1.022	0.58
75_L	92_I	1.021	0.58
36_G	68_G	1.019	0.58
88_G	117_G	1.013	0.57
71_E	139_L	1.005	0.56
70_A	119_L	1.005	0.56
31_S	34_G	1.001	0.56
103_D	113_G	1.001	0.56

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling

HHsearch Results:

PDB	Chains	Cov	P(%)	HHΔ		Acc
3i4oA	2	0.4151	29.5	0.932	Contact Map	0.512
1hr0W	1	0.4088	18	0.939	Contact Map	0.561
1ah9A	1	0.4151	17.2	0.939	Contact Map	0.5
1vehA	1	0.3774	14.8	0.941	Contact Map	0.319
2m5oA	1	0.3836	13.8	0.942	Contact Map	0.083
4awxB	1	0.2516	11.4	0.944	Contact Map	0.473
3j20R	1	0.4088	10.2	0.945	Contact Map	0.419
3m7aA	2	0.3082	9	0.946	Contact Map	0.265
1xhjA	1	0.4025	8.6	0.947	Contact Map	0.122
3iz6P	1	0.5535	6.7	0.949	Contact Map	0

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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